2011
1358 NANOPARTICLE DELIVERY OF THE HISTONE DEACETYLASE INHIBITOR PXD101 FACILITATES BLADDER CANCER CELL UPTAKE AND CYTOTOXICITY
Kaimakliotis H, Martin D, Hoimes C, Cheng C, Liu J, Kelly K, Tew G, Saltzman W, Weiss R. 1358 NANOPARTICLE DELIVERY OF THE HISTONE DEACETYLASE INHIBITOR PXD101 FACILITATES BLADDER CANCER CELL UPTAKE AND CYTOTOXICITY. Journal Of Urology 2011, 185: e542. DOI: 10.1016/j.juro.2011.02.1180.Peer-Reviewed Original Research
2010
1153 EFFECT OF MITOMYCIN C ON LEVELS OF VASCULAR ENDOTHELIAL GROWTH FACTOR AND ITS RECEPTORS IN BLADDER CANCER CELLS AND IN BLADDERS OF RATS INTRAVESICALLY INSTILLED WITH MITOMYCIN C
Verma A, Wheeler M, DeGrado J, Kaimakliotis H, Hittelman A, Weiss R. 1153 EFFECT OF MITOMYCIN C ON LEVELS OF VASCULAR ENDOTHELIAL GROWTH FACTOR AND ITS RECEPTORS IN BLADDER CANCER CELLS AND IN BLADDERS OF RATS INTRAVESICALLY INSTILLED WITH MITOMYCIN C. Journal Of Urology 2010, 183: e446-e447. DOI: 10.1016/j.juro.2010.02.652.Peer-Reviewed Original Research
2005
Regulation of cyclic nucleotides in the urinary tract
Wheeler MA, Ayyagari RR, Wheeler GL, Weiss RM. Regulation of cyclic nucleotides in the urinary tract. Journal Of Smooth Muscle Research 2005, 41: 1. PMID: 15855736, DOI: 10.1540/jsmr.41.1.Peer-Reviewed Original ResearchConceptsUrinary tractRelaxation responseLow compliance bladderSmooth muscle functionG proteinsCyclic AMP productionStimulatory G proteinCyclic nucleotide levelsG protein isoformsUrge incontinenceTreatment optionsProstate cancerMuscle functionDisease processFamily of phosphodiesterasesSpecific PDE inhibitorsAMP productionPDE inhibitorsBladderAdenylyl cyclasePDE isoformsTractPharmacological potentialCancerPDE expression
2000
Alterations in G-proteins and beta-adrenergic responsive adenylyl cyclase in rat urinary bladder during aging.
Derweesh I, Wheeler M, Weiss R. Alterations in G-proteins and beta-adrenergic responsive adenylyl cyclase in rat urinary bladder during aging. Journal Of Pharmacology And Experimental Therapeutics 2000, 294: 969-74. PMID: 10945848.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine Diphosphate RiboseAdenylate Cyclase ToxinAdenylyl CyclasesAdrenergic beta-AgonistsAgingAnimalsBlotting, WesternCarbazolesColforsinCyclic AMPCyclic AMP-Dependent Protein KinasesEnzyme InhibitorsGTP-Binding ProteinsIndolesIsoproterenolMuscle, SmoothPertussis ToxinPyrrolesRatsReceptors, Adrenergic, betaUrinary BladderVirulence Factors, BordetellaConceptsPertussis toxin-catalyzed ADP-ribosylationToxin-catalyzed ADP-ribosylationRat bladderPertussis toxin-sensitive G proteinToxin-sensitive G proteinResponses of bladdersRat urinary bladderAdenylyl cyclaseTreatment of bladderBeta-adrenergic stimulationADP-ribosylationG proteinsAdenylyl cyclase activityResponsive adenylyl cyclaseAge-dependent declineWestern blot analysisG-protein contentUrinary bladderPertussis toxinBladderIsoproterenol stimulationRelaxation responseCyclase activityFunctional activityBlot analysis
1997
Age-dependent changes in particulate and soluble guanylyl cyclase activities in urinary tract smooth muscle
Wheeler M, Pontari M, Dokita S, Nishimoto T, Cho Y, Hong K, Weiss R. Age-dependent changes in particulate and soluble guanylyl cyclase activities in urinary tract smooth muscle. Molecular And Cellular Biochemistry 1997, 169: 115-124. PMID: 9089638, DOI: 10.1023/a:1006823611864.Peer-Reviewed Original ResearchConceptsSoluble guanylyl cyclase activityAdult guinea pigsGuanylyl cyclase activityCyclase activityBladder domeSodium nitroprussideGuinea pigsUrinary tract smooth muscleGuanylyl cyclaseAtrial natriuretic factorParticulate guanylyl cyclaseAge-dependent changesAge-specific differencesUrinary tractNatriuretic factorSmooth muscleUreterUrethraRelaxation responseBladderInduced activationNitroprussideTissueRank orderAge
1995
Enhancement of muscarinic receptor-coupled phosphatidyl inositol hydrolysis in diabetic bladder
Mimata H, Wheeler M, Fukumoto Y, Takigawa H, Nishimoto T, Weiss R, Latifpour J. Enhancement of muscarinic receptor-coupled phosphatidyl inositol hydrolysis in diabetic bladder. Molecular And Cellular Biochemistry 1995, 152: 71-76. PMID: 8609914, DOI: 10.1007/bf01076465.Peer-Reviewed Original ResearchConceptsDiabetic bladderRat bladderAltered functional responseControl rat bladdersCarbachol-induced increaseMuscarinic receptor densityPhosphatidyl inositol hydrolysisMuscarinic agonist stimulationSucrose-fed animalsRat detrusorContractile responseInositol phosphate productionMuscarinic receptorsMuscarinic agonistsReceptor densityBladderAgonist stimulationPhosphatidylinositol metabolismInositol uptakeEC50 valuesSignal transduction pathwaysPhosphate productionTransduction pathwaysDetrusorStreptozotocin
1991
Differential regulation of bladder beta-adrenergic and muscarinic cholinergic receptors in experimental diabetes
Latifpour J, Nishimoto T, Marian M, Yoshida M, Weiss R. Differential regulation of bladder beta-adrenergic and muscarinic cholinergic receptors in experimental diabetes. Diabetes 1991, 40: 1150-1156. DOI: 10.2337/diabetes.40.9.1150.Peer-Reviewed Original Research
1981
Urinary undiversion in patients with myelodysplasia and neurogenic bladder dysfunction Report of a Workshop
Borden T, McGuire E, Woodside J, Allen T, Bauer S, Firlit C, Gonzales E, Kaplan W, King L, Klauber G, Perlmutter A, Thornbury J, Weiss R. Urinary undiversion in patients with myelodysplasia and neurogenic bladder dysfunction Report of a Workshop. Urology 1981, 18: 223-228. PMID: 7025417, DOI: 10.1016/0090-4295(81)90349-6.Peer-Reviewed Original ResearchConceptsUrinary undiversionReasonable surgical treatmentSuch reconstructive surgeryNeurogenic bladder dysfunctionBladder dysfunctionNeurogenic bladderAbsolute contraindicationSelect patientsMyelodysplastic patientsSurgical treatmentUrinary diversionReconstructive surgeryUndiversionPatientsRole of reconstructionContraindicationsBladderReportMyelodysplasiaSurgeryDysfunctionEvaluation
1976
Management of Urinary Fistulas after Renal Transplantation
Schiff M, Mcguire E, Weiss R, Lytton B. Management of Urinary Fistulas after Renal Transplantation. Journal Of Urology 1976, 115: 251-256. PMID: 768526, DOI: 10.1016/s0022-5347(17)59160-0.Peer-Reviewed Original ResearchTreatment of Autonomic Dysreflexia with Phenoxybenz Amine
Mcguire E, Wagner F, Weiss R. Treatment of Autonomic Dysreflexia with Phenoxybenz Amine. Journal Of Urology 1976, 115: 53-55. PMID: 1246113, DOI: 10.1016/s0022-5347(17)59065-5.Peer-Reviewed Original Research