1995
Age-dependent Alterations in beta-adrenergic Responsiveness of Rat Detrusor Smooth Muscle
Nishimoto T, Latifpour J, Wheeler M, Yoshida M, Weiss R. Age-dependent Alterations in beta-adrenergic Responsiveness of Rat Detrusor Smooth Muscle. Journal Of Urology 1995, 153: 1701-1705. PMID: 7715014, DOI: 10.1016/s0022-5347(01)67508-6.Peer-Reviewed Original ResearchConceptsElectrical field stimulationMaximum relaxant responseBeta-adrenergic receptorsMuscle stripsRelaxant responsesRelaxant effectTonic contractionMaximal KCl-induced contractionRat detrusor smooth muscleAge groupsMale Fischer 344 ratsDetrusor muscle stripsEFS-induced contractionsKCl-induced contractionBeta-adrenergic responsivenessDetrusor smooth muscleFischer 344 ratsBeta-adrenergic stimulationAge-dependent alterationsAge-related decreaseCyclic AMP productionDibutyryl cyclic AMPRat detrusorPhasic contractionsBladder detrusorAge-dependent Alterations in beta-adrenergic Responsiveness of Rat Detrusor Smooth Muscle
Nishimoto T, Latifpour J, Wheeler M, Yoshida M, Weiss R. Age-dependent Alterations in beta-adrenergic Responsiveness of Rat Detrusor Smooth Muscle. Journal Of Urology 1995, 153: 1701-1705.. DOI: 10.1097/00005392-199505000-00105.Peer-Reviewed Original ResearchElectrical field stimulationMaximum relaxant responseBeta-adrenergic receptorsMuscle stripsRelaxant responsesRelaxant effectTonic contractionMaximal KCl-induced contractionRat detrusor smooth muscleAge groupsCholera toxinMale Fischer 344 ratsDetrusor muscle stripsEFS-induced contractionsKCl-induced contractionBeta-adrenergic responsivenessDetrusor smooth muscleFischer 344 ratsBeta-adrenergic stimulationAge-dependent alterationsAge-related decreaseCyclic AMP productionDibutyryl cyclic AMPRat detrusorPhasic contractions
1986
Relaxant Effect of Forskolin in Rabbit Detrusor Smooth Muscle: Role of Cyclic AMP
Morita T, Wheeler M, Weiss R. Relaxant Effect of Forskolin in Rabbit Detrusor Smooth Muscle: Role of Cyclic AMP. Journal Of Urology 1986, 135: 1293-1295. PMID: 3012124, DOI: 10.1016/s0022-5347(17)46077-0.Peer-Reviewed Original ResearchConceptsDetrusor muscleRelaxant effectRabbit detrusor muscle stripsDetrusor muscle relaxationDetrusor muscle stripsRabbit detrusor muscleConcentration-dependent relaxationDetrusor smooth muscleRabbit detrusor smooth muscleBeta-adrenergic antagonistsBeta-adrenergic receptorsCyclic AMPCyclic AMP levelsAdenylate cyclase inhibitorRabbit detrusorMuscle stripsMuscle relaxationSmooth muscleCyclase inhibitorPhosphodiesterase inhibitorRelaxation responseAMP levelsAdenylate cyclaseDependent relaxationForskolin