1991
Pharmacological characterization of alpha adrenergic receptors in the young and old female rabbit urethra.
Yoshida M, Latifpour J, Nishimoto T, Weiss R. Pharmacological characterization of alpha adrenergic receptors in the young and old female rabbit urethra. Journal Of Pharmacology And Experimental Therapeutics 1991, 257: 1100-8. PMID: 1675287.Peer-Reviewed Original ResearchConceptsConcentration-response curvesFemale rabbit urethraContractile responseAdrenergic receptorsRabbit urethraAge groupsAlpha-2 adrenergic receptorsED50 valuesEmax valuesConcentration-dependent contractionsMaximum contractile responsePhenylephrine-induced contractionAlpha-adrenergic receptorsAlpha 1B subtypeMuscle bath techniqueYounger age groupsAge-dependent differencesPharmacological characterizationClonidinePharmacological characteristicsOxymetazolinePhenylephrineNorepinephrineFree bufferAlpha 1
1989
Effects of experimental diabetes on biochemical and functional characteristics of bladder muscarinic receptors.
Latifpour J, Gousse A, Kondo S, Morita T, Weiss R. Effects of experimental diabetes on biochemical and functional characteristics of bladder muscarinic receptors. Journal Of Pharmacology And Experimental Therapeutics 1989, 248: 81-8. PMID: 2913290.Peer-Reviewed Original ResearchConceptsMuscarinic receptorsBladder domeDiabetic animalsMuscarinic agonistsExperimental diabetesRat bladder smooth muscleED50 valuesHigher serum glucose levelsBladder muscarinic receptorsLarger contractile responsesMuscarinic receptor propertiesAF-DX 116Serum insulin levelsSerum glucose levelsBladder smooth muscleM2 muscarinic receptorsAge-matched controlsLower body weightReceptor binding studiesBladder dysfunctionContractile responseCommon complicationDiabetes mellitusPeripheral neuropathyUrine output