2003
Developmental changes in the functional, biochemical and molecular properties of rat bladder endothelin receptors
Afiatpour P, Latifpour J, Takahashi W, Yono M, Foster HE, Ikeda K, Pouresmail M, Weiss RM. Developmental changes in the functional, biochemical and molecular properties of rat bladder endothelin receptors. Naunyn-Schmiedeberg's Archives Of Pharmacology 2003, 367: 462-472. PMID: 12700883, DOI: 10.1007/s00210-003-0715-6.Peer-Reviewed Original ResearchMeSH KeywordsAgingAnimalsAutoradiographyBinding SitesEndothelin-1Gene ExpressionIodine RadioisotopesMuscle ContractionMuscle, SmoothRadioligand AssayRatsRats, Inbred F344Receptor, Endothelin AReceptor, Endothelin BReverse Transcriptase Polymerase Chain ReactionRNA, MessengerTime FactorsUrinary BladderConceptsETA receptor subtypeSmooth muscle layerReceptor subtypesRat detrusorEndothelin receptorsET receptorsET-1Muscle layerSelective ETA receptor antagonistET receptor systemLarger contractile responsesTotal ET receptorsReceptor subtype mRNAsETA receptor antagonistETB receptor subtypesReal-time reverse transcription-polymerase chain reactionMuscle bath techniqueBladder smooth muscleReverse transcription-polymerase chain reactionTranscription-polymerase chain reactionAge-dependent decreaseAge-dependent alterationsReal-time RT-PCRContractile responseSubtype mRNAs
2000
AGE-RELATED CHANGES IN CONTRACTILE RESPONSES OF RABBIT LOWER URINARY TRACT TO ENDOTHELIN
WADA Y, LATIFPOUR J, SANEMATSU H, AFIATPOUR P, WANG Z, SAITO M, NISHI K, WEISS R. AGE-RELATED CHANGES IN CONTRACTILE RESPONSES OF RABBIT LOWER URINARY TRACT TO ENDOTHELIN. Journal Of Urology 2000, 164: 806-813. PMID: 10953160, DOI: 10.1097/00005392-200009010-00054.Peer-Reviewed Original ResearchConceptsRabbit lower urinary tractSmooth muscle layerContractile responseLower urinary tractMonth-old rabbitsBladder domeUrinary tractET receptorsET-1Muscle layerMuscle stripsReceptor antagonistOld rabbitsReceptor subtypesMonths old male rabbitsSelective ETA receptor antagonistSelective ETB receptor antagonistMammalian urinary tractMediation of contractionSignificant contractile responseUrethral muscle stripsMaximal contractile responseET receptor subtypesETA receptor antagonistMaximum contractile responseAGE-RELATED CHANGES IN CONTRACTILE RESPONSES OF RABBIT LOWER URINARY TRACT TO ENDOTHELIN
WADA Y, LATIFPOUR J, SANEMATSU H, AFIATPOUR P, WANG Z, SAITO M, NISHI K, WEISS R. AGE-RELATED CHANGES IN CONTRACTILE RESPONSES OF RABBIT LOWER URINARY TRACT TO ENDOTHELIN. Journal Of Urology 2000, 164: 806-813. DOI: 10.1016/s0022-5347(05)67319-3.Peer-Reviewed Original ResearchConceptsRabbit lower urinary tractSmooth muscle layerContractile responseLower urinary tractMonth-old rabbitsBladder domeUrinary tractET receptorsET-1Muscle layerMuscle stripsReceptor antagonistOld rabbitsReceptor subtypesMonths old male rabbitsSelective ETA receptor antagonistSelective ETB receptor antagonistMammalian urinary tractMediation of contractionSignificant contractile responseUrethral muscle stripsMaximal contractile responseET receptor subtypesETA receptor antagonistMaximum contractile response
1995
Regional differences in the density and subtype specificity of endothelin receptors in rabbit urinary tract
Latifpour J, Fukumoto Y, Weiss R. Regional differences in the density and subtype specificity of endothelin receptors in rabbit urinary tract. Naunyn-Schmiedeberg's Archives Of Pharmacology 1995, 352: 459-468. PMID: 8751073, DOI: 10.1007/bf00169378.Peer-Reviewed Original ResearchConceptsBladder baseSarafotoxin S6cBladder domeUrinary tractETB receptorsET-3Rabbit urinary tractSubtype specificityBQ-123Endothelin receptorsET receptorsReceptor subtypesET-1Human ETASelective ETA receptor antagonistSelective ETB agonistETA receptor antagonistETB receptor subtypesSingle receptor subtypeETA receptorsETB agonistChinese hamster ovary KReceptor antagonistSimilar binding studiesUrethra