2001
Regulatory effect of experimental diabetes on the expression of endothelin receptor subtypes and their gene transcripts in the rat adrenal gland
Ikeda K, Wada Y, Sanematsu H, Foster HE, Shin D, Weiss RM, Latifpour J. Regulatory effect of experimental diabetes on the expression of endothelin receptor subtypes and their gene transcripts in the rat adrenal gland. Journal Of Endocrinology 2001, 168: 163-175. PMID: 11139780, DOI: 10.1677/joe.0.1680163.Peer-Reviewed Original ResearchConceptsEndothelin-converting enzyme-1Rat adrenal glandET receptor subtypesInduction of diabetesAdrenal glandReceptor subtypesETB receptorsExperimental diabetesAge-matched control ratsECE-1 mRNA levelsET-3 mRNAPredominant receptor subtypeDiabetes-induced changesEndothelin receptor subtypesInsulin-treated diabeticsSecretion of steroidsReceptor subtypes ETARadioligand receptor bindingAdrenal gland sizeET-1 mRNAExpression levelsRegulatory effectsVascular toneET receptorsEndothelin action
2000
EXPERIMENTAL DIABETES-INDUCED REGRESSION OF THE RAT PROSTATE IS ASSOCIATED WITH AN INCREASED EXPRESSION OF TRANSFORMING GROWTH FACTOR-β
IKEDA K, WADA Y, FOSTER H, WANG Z, WEISS R, LATIFPOUR J. EXPERIMENTAL DIABETES-INDUCED REGRESSION OF THE RAT PROSTATE IS ASSOCIATED WITH AN INCREASED EXPRESSION OF TRANSFORMING GROWTH FACTOR-β. Journal Of Urology 2000, 164: 180-185. DOI: 10.1097/00005392-200007000-00057.Peer-Reviewed Original ResearchSerum testosterone levelsDiabetic rat prostateTGF-β1TGF-β2Testosterone levelsRat prostateProstatic weightGrowth factorProtein levelsStromal cellsAge-matched control ratsInsulin-treated diabeticsProstatic stromal cellsSemi-quantitative Western blottingTGF-β2 expressionTransforming Growth FactorAndrogen-dependent processesExperimental diabetesMultiplex RT-PCRControl ratsImmunohistochemical studyProstate glandProstateIncreased expressionResults InductionEXPERIMENTAL DIABETES-INDUCED REGRESSION OF THE RAT PROSTATE IS ASSOCIATED WITH AN INCREASED EXPRESSION OF TRANSFORMING GROWTH FACTOR-β
IKEDA K, WADA Y, FOSTER H, WANG Z, WEISS R, LATIFPOUR J. EXPERIMENTAL DIABETES-INDUCED REGRESSION OF THE RAT PROSTATE IS ASSOCIATED WITH AN INCREASED EXPRESSION OF TRANSFORMING GROWTH FACTOR-β. Journal Of Urology 2000, 164: 180-185. PMID: 10840456, DOI: 10.1016/s0022-5347(05)67491-5.Peer-Reviewed Original ResearchConceptsSerum testosterone levelsDiabetic rat prostateTestosterone levelsRat prostateProstatic weightProtein levelsStromal cellsAge-matched control ratsGrowth factorInsulin-treated diabeticsInduction of diabetesProstatic stromal cellsSemi-quantitative Western blottingTGF-beta expressionTGF-beta2 expressionTransforming Growth FactorAndrogen-dependent processesExperimental diabetesMultiplex RT-PCRControl ratsImmunohistochemical studyTGF-beta2TGF-beta1Prostate glandProstate
1993
The Reversal Effect of Insulin on Diabetes-Induced Alterations In Beta Adrenergic and Muscarinic Receptors in Rat Prostate
Fukumoto Y, Yoshida M, Dokita S, Kamai T, Weiss R, Latifpour J. The Reversal Effect of Insulin on Diabetes-Induced Alterations In Beta Adrenergic and Muscarinic Receptors in Rat Prostate. Journal Of Urology 1993, 149: 1602-1606. PMID: 8388963, DOI: 10.1016/s0022-5347(17)36459-5.Peer-Reviewed Original ResearchConceptsMuscarinic cholinergic receptorsBeta adrenergicRat prostateCholinergic receptorsInsulin treatmentMuscarinic receptorsInsulin-treated diabetic animalsEarly insulin treatmentDiabetes-induced alterationsInduction of diabetesInsulin-treated diabeticsOnset of diabetesAdministration of streptozotocinDiabetes-induced downregulationDiabetic rat prostateGroups of ratsBeta-adrenergic agonistsHigh-affinity agonistDiabetic animalsMuscarinic agonistsAdrenergic agonistsAdrenergicProstateDiabetesAgonists
1991
Beta adrenergic receptor alterations in diabetic rat prostate: Effects of insulin and dietary myoinositol
Gousse A, Yoshida M, Weiss R, Latifpour J. Beta adrenergic receptor alterations in diabetic rat prostate: Effects of insulin and dietary myoinositol. The Prostate 1991, 19: 121-131. PMID: 1681523, DOI: 10.1002/pros.2990190205.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAnimalsBlood GlucoseBody WeightDiabetes Mellitus, ExperimentalDihydroalprenololDose-Response Relationship, DrugDrinkingInositolInsulinIsoproterenolMaleOrgan SizePropanolaminesPropranololProstateRadioligand AssayRatsRats, Inbred StrainsReceptors, Adrenergic, betaStreptozocinUrinationConceptsBeta-adrenergic receptorsAdrenergic receptorsInsulin levelsRadioligand receptor binding techniquesSelective beta-adrenergic antagonistsHigh blood glucose levelsLower serum insulin levelsAdrenergic receptor alterationsInduction of diabetesInsulin-treated diabeticsSerum insulin levelsBeta-adrenergic receptor alterationsAutonomic nervous systemBlood glucose levelsBeta-adrenergic antagonistsDiabetic rat prostateGroups of ratsReceptor binding techniquesEffect of insulinMale reproductive systemHigh water intakeDietary myoinositolDiabetes mellitusUrine outputDiabetic rats