EFFECT OF LONG-TERM ORAL L-ARGININE ON THE NITRIC OXIDE SYNTHASE PATHWAY IN THE URINE FROM PATIENTS WITH INTERSTITIAL CYSTITIS
Wheeler M, Smith S, Saito N, Foster H, Weiss R. EFFECT OF LONG-TERM ORAL L-ARGININE ON THE NITRIC OXIDE SYNTHASE PATHWAY IN THE URINE FROM PATIENTS WITH INTERSTITIAL CYSTITIS. Journal Of Urology 1997, 158: 2045-2050. PMID: 9366309, DOI: 10.1016/s0022-5347(01)68150-3.Peer-Reviewed Original ResearchConceptsInterstitial cystitis patientsNitric oxide synthase activityOral L-arginineOxide synthase activityInterstitial cystitisCystitis patientsL-arginineIL-8Oral L-arginine treatmentLong-term oral administrationInducible nitric oxide synthase (iNOS) proteinNitric oxideNitric oxide synthase proteinCyclic guanosine monophosphate levelsNitric oxide synthase pathwayUrinary nitric oxideInterstitial cystitis symptomsL-arginine treatmentInterleukin-8 levelsCytokine IL-8Nitric oxide synthaseSmooth muscle relaxationUrine of patientsGuanosine monophosphate levelsOxide synthase pathwayImprovement in Interstitial Cystitis Symptom Scores During Treatment With Oral L-Arginine
Smith S, Wheeler M, Foster H, Weiss R. Improvement in Interstitial Cystitis Symptom Scores During Treatment With Oral L-Arginine. Journal Of Urology 1997, 158: 703-708.. PMID: 9258064, DOI: 10.1097/00005392-199709000-00005.Peer-Reviewed Original ResearchConceptsOral L-arginineL-arginineInterstitial cystitisUrinary nitric oxide synthase activityInterstitial Cystitis Symptom ScoreOral L-arginine treatmentNitric oxide synthase activityLower abdominal painInterstitial cystitis symptomsMethods Ten patientsL-arginine treatmentOxide synthase activityNitric oxide synthaseSelf-controlled studyAbdominal painTEN patientsUrethral painUrinary frequencyCystitis symptomsSymptom scoresOxide synthaseRelated symptomsImmunological responseNitric oxidePatients