Enhancement of muscarinic receptor-coupled phosphatidyl inositol hydrolysis in diabetic bladder
Mimata H, Wheeler M, Fukumoto Y, Takigawa H, Nishimoto T, Weiss R, Latifpour J. Enhancement of muscarinic receptor-coupled phosphatidyl inositol hydrolysis in diabetic bladder. Molecular And Cellular Biochemistry 1995, 152: 71-76. PMID: 8609914, DOI: 10.1007/bf01076465.Peer-Reviewed Original ResearchConceptsDiabetic bladderRat bladderAltered functional responseControl rat bladdersCarbachol-induced increaseMuscarinic receptor densityPhosphatidyl inositol hydrolysisMuscarinic agonist stimulationSucrose-fed animalsRat detrusorContractile responseInositol phosphate productionMuscarinic receptorsMuscarinic agonistsReceptor densityBladderAgonist stimulationPhosphatidylinositol metabolismInositol uptakeEC50 valuesSignal transduction pathwaysPhosphate productionTransduction pathwaysDetrusorStreptozotocinEffect of Carbachol and Norepinephrine on Phosphatidyl Inositol Hydrolysis and Cyclic Amp Levels in Guinea Pig Urinary Tract
Wheeler M, Martin T, Weiss R. Effect of Carbachol and Norepinephrine on Phosphatidyl Inositol Hydrolysis and Cyclic Amp Levels in Guinea Pig Urinary Tract. Journal Of Urology 1995, 153: 2044-2049. PMID: 7752391, DOI: 10.1016/s0022-5347(01)67399-3.Peer-Reviewed Original ResearchConceptsPhosphatidyl inositol hydrolysisPI hydrolysisCyclic AMP levelsCAMP levelsBladder domeAMP levelsUrinary tract functionEffect of carbacholGuinea-pig ureterAgonist-induced changesBasal cAMP levelsUrinary tractMuscarinic cholinergicTract functionSecond messenger systemsCarbacholNorepinephrinePig ureterSustained increaseUreterUrethraSecond messenger levelsMessenger systemsForskolinTransitory increaseEffect of Carbachol and Norepinephrine on Phosphatidyl Inositol Hydrolysis and Cyclic Amp Levels in Guinea Pig Urinary Tract
Wheeler M, Martin T, Weiss R. Effect of Carbachol and Norepinephrine on Phosphatidyl Inositol Hydrolysis and Cyclic Amp Levels in Guinea Pig Urinary Tract. Journal Of Urology 1995, 153: 2044-2049.. DOI: 10.1097/00005392-199506000-00100.Peer-Reviewed Original ResearchPhosphatidyl inositol hydrolysisPI hydrolysisCyclic AMP levelsCAMP levelsBladder domeAMP levelsUrinary tract functionEffect of carbacholGuinea-pig ureterAgonist-induced changesBasal cAMP levelsUrinary tractMuscarinic cholinergicSecond messenger systemsTract functionCarbacholNorepinephrinePig ureterSustained increaseUreterUrethraSecond messenger levelsMessenger systemsForskolinMessenger levels