2006
Age Related Changes in the Functional, Biochemical and Molecular Properties of α1-Adrenoceptors in the Rat Genitourinary Tract
Yono M, Foster HE, Weiss RM, Latifpour J. Age Related Changes in the Functional, Biochemical and Molecular Properties of α1-Adrenoceptors in the Rat Genitourinary Tract. Journal Of Urology 2006, 176: 1214-1219. PMID: 16890728, DOI: 10.1016/j.juro.2006.04.038.Peer-Reviewed Original ResearchConceptsRat genitourinary tractLower urinary tract symptomsUrinary tract symptomsBenign prostatic hyperplasiaAdrenoceptor antagonistGenitourinary tractTract symptomsBladder baseProstatic hyperplasiaDorsolateral prostateYoung ratsIsolated muscle bathMaximum contractile responseTranscriptase-polymerase chain reaction techniqueRadioligand receptor bindingReverse transcriptase-polymerase chain reaction techniqueSignificant age-dependent differencesAge-dependent differencesAge related changesHigher body weightAge related differencesContractile responseAdrenoceptor densityAdrenoceptor subtypesBladder dome
2000
Expression and localization of basic fibroblast growth factor in diabetic rat prostate
Wang Z, Ikeda K, Wada Y, Foster H, Weiss R, Latifpour J. Expression and localization of basic fibroblast growth factor in diabetic rat prostate. BJU International 2000, 85: 945-952. PMID: 10792180, DOI: 10.1046/j.1464-410x.2000.00597.x.Peer-Reviewed Original ResearchConceptsBenign prostatic hyperplasiaDiabetic ratsExpression of FGF2Testosterone levelsRat prostateLow serum testosterone levelsHuman benign prostatic hyperplasiaAge-matched control ratsWestern blottingSerum testosterone levelsPolymerase chain reaction studiesDiabetic rat prostateReverse transcriptase-polymerase chain reaction studiesGroups of ratsBasic fibroblast growth factorImmuno-histochemical studyFibroblast growth factor-2Fibroblast growth factorProstatic sectionsFGF-2 mRNAGrowth factor 2Smaller prostatesProstatic hyperplasiaProstatic sizeProstatic growth