1999
Developmental aspects of endothelin receptors in rabbit lower urinary tract
Saito M, Latifpour J, Weiss R. Developmental aspects of endothelin receptors in rabbit lower urinary tract. Neurourology And Urodynamics 1999, 19: 71-85. PMID: 10602249, DOI: 10.1002/(sici)1520-6777(2000)19:1<71::aid-nau8>3.0.co;2-9.Peer-Reviewed Original ResearchConceptsLower urinary tractRabbit lower urinary tractEndothelin receptorsUrinary tractBladder baseBladder domeMale rabbitsEndothelin receptor subtypesAge-related alterationsOld male rabbitsET receptorsReceptor subtypesPharmacological characterizationPharmacological profileAged rabbitsSubtype specificityReceptorsTractDevelopment-related changesSimilar proportionsWeeksReceptor compoundsUrethraRabbitsRank order
1998
CHARACTERIZATION, LOCALIZATION AND DISTRIBUTION OF alpha1 ADRENOCEPTOR SUBTYPE IN MALE RABBIT URETHRA
NISHI K, LATIFPOUR J, SAITO M, FOSTER H, YOSHIDA M, WEISS R. CHARACTERIZATION, LOCALIZATION AND DISTRIBUTION OF alpha1 ADRENOCEPTOR SUBTYPE IN MALE RABBIT URETHRA. Journal Of Urology 1998, 160: 196-205.. DOI: 10.1097/00005392-199807000-00084.Peer-Reviewed Original ResearchAlpha1 adrenoceptorsMale rabbit urethraRabbit urethraSelective alpha1-adrenoceptor antagonistAnti-alpha smooth muscle actinAlpha1-adrenoceptor antagonistRadioligand receptor bindingSmooth muscle actinLight microscopic autoradiographySingle high-affinity binding siteAdrenoceptor antagonistPharmacological profileAbstract PurposeMuscle actinHigh-affinity binding sitesUrethraSubtype specificityAdrenoceptorsAffinity binding sitesReceptor bindingActin antibodyMicroscopic autoradiographySaturation experimentsInhibition experimentsRank order
1997
Age-dependent changes in particulate and soluble guanylyl cyclase activities in urinary tract smooth muscle
Wheeler M, Pontari M, Dokita S, Nishimoto T, Cho Y, Hong K, Weiss R. Age-dependent changes in particulate and soluble guanylyl cyclase activities in urinary tract smooth muscle. Molecular And Cellular Biochemistry 1997, 169: 115-124. PMID: 9089638, DOI: 10.1023/a:1006823611864.Peer-Reviewed Original ResearchConceptsSoluble guanylyl cyclase activityAdult guinea pigsGuanylyl cyclase activityCyclase activityBladder domeSodium nitroprussideGuinea pigsUrinary tract smooth muscleGuanylyl cyclaseAtrial natriuretic factorParticulate guanylyl cyclaseAge-dependent changesAge-specific differencesUrinary tractNatriuretic factorSmooth muscleUreterUrethraRelaxation responseBladderInduced activationNitroprussideTissueRank orderAge
1994
Diabetes-Induced Alterations in the Properties of Muscarinic Cholinergic Receptors in Rat Vas Deferens
Kamai T, Fukumoto Y, Gousse A, Yoshida M, Davenport T, Weiss R, Latifpour J. Diabetes-Induced Alterations in the Properties of Muscarinic Cholinergic Receptors in Rat Vas Deferens. Journal Of Urology 1994, 152: 1017-1021. PMID: 8051725, DOI: 10.1016/s0022-5347(17)32646-0.Peer-Reviewed Original ResearchConceptsMuscarinic cholinergic receptorsRat vasVas deferensCholinergic receptorsMuscarinic receptorsDiabetic insulin-treated ratsMuscarinic cholinergic receptor subtypesMuscarinic cholinergic receptor densityMembrane particulatesCholinergic receptor densityDiabetes-Induced AlterationsAF-DX 116Cholinergic receptor subtypesMuscarinic cholinergic antagonistAdministration of insulinInsulin-treated ratsAge-matched controlsRat vas deferensRank orderAdditional pharmacological studiesDiabetic ratsBladder domeCerebral cortexCholinergic antagonistsReceptor subtypesInvolvement of nitric oxide and cyclic GMP in rabbit urethral relaxation
Dokita S, Smith S, Nishimoto T, Wheeler M, Weiss R. Involvement of nitric oxide and cyclic GMP in rabbit urethral relaxation. European Journal Of Pharmacology 1994, 266: 269-275. PMID: 7513645, DOI: 10.1016/0922-4106(94)90136-8.Peer-Reviewed Original ResearchConceptsNitric oxide synthase activityTransmural nerve stimulationOxide synthase activityRabbit urethraNerve stimulationNOS activityL-arginineSoluble nitric oxide synthaseNitric oxide synthase inhibitorRelaxation responseNitric oxideCyclic GMPOxide synthase inhibitorNitric oxide synthaseCyclic GMP levelsUrethral relaxationNG-nitroRank orderOxide synthaseSynthase activityNG-methylSynthase inhibitorElectrical stimulationUrethraSame rank order
1993
Age-related changes in Ca2+ channel antagonist receptors in rabbit lower urinary tract
Yoshida M, Latifpour J, Weiss R. Age-related changes in Ca2+ channel antagonist receptors in rabbit lower urinary tract. European Journal Of Pharmacology 1993, 232: 159-167. PMID: 8385616, DOI: 10.1016/0014-2999(93)90769-e.Peer-Reviewed Original ResearchConceptsLower urinary tractBladder baseBladder domeUrinary tractChannel antagonistsRabbit lower urinary tractBay K 8644Channel antagonist receptorsAge-dependent changesDensity of Ca2Age-related changesAntagonist binding sitesReceptor densityPharmacological profileAntagonist receptorsRabbit urethraUrethraAge groupsBmax valuesDays rabbitsAntagonistTractWeeksRank orderBinding sites
1989
Characterization of Autonomic Receptors in Neonatal Urinary Tract Smooth Muscle
Latifpour J, Morita T, O'Hollaren B, Kondo S, Weiss R. Characterization of Autonomic Receptors in Neonatal Urinary Tract Smooth Muscle. Neonatology 1989, 13: 1-10. PMID: 2570683, DOI: 10.1159/000457575.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic AgonistsAnimalsAnimals, NewbornCarbacholClonidineDihydroalprenololDose-Response Relationship, DrugIn Vitro TechniquesMuscle ContractionMuscle, SmoothPrazosinQuinuclidinyl BenzilateRabbitsReceptors, Adrenergic, alphaReceptors, Adrenergic, betaReceptors, MuscarinicUrinary TractYohimbineConceptsUrinary tract smooth muscleSmooth muscleAutonomic receptorsBeta-adrenergic receptor densityAlpha-1 adrenergic receptorsNeonatal urinary tractAlpha 2 receptorsAlpha 1 receptorsAlpha-adrenergic agonistsFunctional muscarinic receptorsRelaxant responsesBladder baseBladder domeMuscarinic receptorsUrinary tractReceptor densityAdult rabbitsAlpha 2ReceptorsMuscleAgonistsRank orderRabbitsHigher numberIsoproterenol