1989
Effects of experimental diabetes on biochemical and functional characteristics of bladder muscarinic receptors.
Latifpour J, Gousse A, Kondo S, Morita T, Weiss R. Effects of experimental diabetes on biochemical and functional characteristics of bladder muscarinic receptors. Journal Of Pharmacology And Experimental Therapeutics 1989, 248: 81-8. PMID: 2913290.Peer-Reviewed Original ResearchConceptsMuscarinic receptorsBladder domeDiabetic animalsMuscarinic agonistsExperimental diabetesRat bladder smooth muscleED50 valuesHigher serum glucose levelsBladder muscarinic receptorsLarger contractile responsesMuscarinic receptor propertiesAF-DX 116Serum insulin levelsSerum glucose levelsBladder smooth muscleM2 muscarinic receptorsAge-matched controlsLower body weightReceptor binding studiesBladder dysfunctionContractile responseCommon complicationDiabetes mellitusPeripheral neuropathyUrine output
1987
Sex differences in function and distribution of alpha 1- and alpha 2-adrenoceptors in rabbit urethra
Morita T, Latifpour J, O'Hollaren B, Wheeler M, Weiss R. Sex differences in function and distribution of alpha 1- and alpha 2-adrenoceptors in rabbit urethra. American Journal Of Physiology 1987, 252: f1124-f1128. PMID: 3035945, DOI: 10.1152/ajprenal.1987.252.6.f1124.Peer-Reviewed Original ResearchConceptsContractile responseFemale urethraMale urethraAlpha 1Rabbit urethraRadioligand receptor binding techniquesFemale rabbit urethraLarger contractile responsesSmall contractile responseAlpha-adrenergic agonistsUrethral smooth muscleReceptor binding techniquesReceptor binding studiesIsolated urethraSmooth muscleContractile propertiesUrethraFemale rabbitsContractile forceAgonistsInduced increasesAlpha 2Binding techniquesNorepinephrineAlpha