2007
Regional differences in the functional and biochemical properties of endothelin receptor subtypes in the rabbit prostatic urethra
Wada Y, Takahashi W, Latifpour J, Yamada, Kai N, Honda J, Nakanishi J, Weiss RM. Regional differences in the functional and biochemical properties of endothelin receptor subtypes in the rabbit prostatic urethra. BJU International 2007, 100: 430-437. PMID: 17559559, DOI: 10.1111/j.1464-410x.2007.07064.x.Peer-Reviewed Original ResearchConceptsContractile responseET receptor subtypesMaximum contractile responseProstatic urethraReceptor subtypesET-3ET receptorsET-1High-affinity binding sitesConcentration-dependent contractile responsesSubtype specificityEndothelin receptor subtypesSmooth muscle stripsReceptor-binding techniquesRegion-specific differencesEndothelin receptorsMuscle stripsRegional differencesDistal regionUrethraSubtypesReceptorsBQ123Low affinity constantInhibition experiments
1991
NG-nitro-L-arginine inhibits non-adrenergic, non-cholinergic relaxation in rabbit urethral smooth muscle
Dokita S, Morgan W, Wheeler M, Yoshida M, Latifpour J, Weiss R. NG-nitro-L-arginine inhibits non-adrenergic, non-cholinergic relaxation in rabbit urethral smooth muscle. Life Sciences 1991, 48: 2429-2436. PMID: 1675415, DOI: 10.1016/0024-3205(91)90377-n.Peer-Reviewed Original ResearchConceptsElectrical field stimulationRelaxation responseNG-nitroField stimulationL-arginineSelective cyclic GMP phosphodiesterase inhibitorNitric oxideNon-cholinergic relaxationRabbit urethral smooth muscleNon-cholinergic nervesUrethral smooth muscleUrethral smooth muscle stripsSmooth muscle stripsL-arginine inhibitsSoluble guanylate cyclaseNitric oxide biosynthesisCyclic GMP phosphodiesterase inhibitorMuscle stripsSmooth musclePhosphodiesterase inhibitorGuanylate cyclaseCyclic GMPStimulationInhibitorsResponse