2005
A Survivin Gene Signature Predicts Aggressive Tumor Behavior
Salz W, Eisenberg D, Plescia J, Garlick DS, Weiss RM, Wu XR, Sun TT, Altieri DC. A Survivin Gene Signature Predicts Aggressive Tumor Behavior. Cancer Research 2005, 65: 3531-3534. PMID: 15867343, DOI: 10.1158/0008-5472.can-04-4284.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsButylhydroxybutylnitrosamineCarcinogensDisease ProgressionFemaleGene Expression ProfilingGene Expression Regulation, NeoplasticHumansInhibitor of Apoptosis ProteinsMembrane ProteinsMiceMice, TransgenicMicrotubule-Associated ProteinsNeoplasm ProteinsPolymerase Chain ReactionSurvivinTransgenesTumor Suppressor Protein p53Urinary BladderUrinary Bladder NeoplasmsUroplakin IIConceptsTransgenic expressionGene signatureGlobal transcriptional changesDominant negative mutantGene expression profilesSuch genesTumor progressionTranscriptional changesCell divisionEssential regulatorGene expressionExpression profilesTransgenic animalsExtracellular matrixTissue microenvironmentAggressive tumor behaviorPreferential incidenceGenesInflammatory genesSurvivinExpressionTumor behaviorSurvivin expressionAssociated gene signaturesTransgenic model
2003
Effect of Intravesical Treatment of Transitional Cell Carcinoma With Bacillus Calmette-Guerin and Mitomycin C on Urinary Survivin Levels and Outcome
HAUSLADEN DA, WHEELER MA, ALTIERI DC, COLBERG JW, WEISS RM. Effect of Intravesical Treatment of Transitional Cell Carcinoma With Bacillus Calmette-Guerin and Mitomycin C on Urinary Survivin Levels and Outcome. Journal Of Urology 2003, 170: 230-234. PMID: 12796695, DOI: 10.1097/01.ju.0000063685.29339.24.Peer-Reviewed Original ResearchMeSH KeywordsAdjuvants, ImmunologicAdministration, IntravesicalAgedAged, 80 and overAntibiotics, AntineoplasticAntigens, NeoplasmBCG VaccineBiomarkers, TumorCarcinoma, Transitional CellFemaleHumansImmunoblottingInhibitor of Apoptosis ProteinsMaleMicrotubule-Associated ProteinsMiddle AgedMitomycinNeoplasm ProteinsNeoplasm Recurrence, LocalPredictive Value of TestsPrognosisSurvivinTreatment OutcomeUrinary Bladder NeoplasmsConceptsTransitional cell carcinomaCompletion of treatmentBacillus Calmette-GuerinUrinary survivin levelsSurvivin levelsTCC recurrenceCalmette-GuerinUrine survivinIntravesical treatmentIntravesical instillationCell carcinomaMitomycin CRecurrent transitional cell carcinomaPrognostic molecular markersHigher survivin levelsUrinary survivinPosttreatment valuesRecurrenceMonthsHigher likelihoodSurvivinRemissionUrineTreatmentInstillation