2003
Effect of Intravesical Treatment of Transitional Cell Carcinoma With Bacillus Calmette-Guerin and Mitomycin C on Urinary Survivin Levels and Outcome
HAUSLADEN DA, WHEELER MA, ALTIERI DC, COLBERG JW, WEISS RM. Effect of Intravesical Treatment of Transitional Cell Carcinoma With Bacillus Calmette-Guerin and Mitomycin C on Urinary Survivin Levels and Outcome. Journal Of Urology 2003, 170: 230-234. PMID: 12796695, DOI: 10.1097/01.ju.0000063685.29339.24.Peer-Reviewed Original ResearchMeSH KeywordsAdjuvants, ImmunologicAdministration, IntravesicalAgedAged, 80 and overAntibiotics, AntineoplasticAntigens, NeoplasmBCG VaccineBiomarkers, TumorCarcinoma, Transitional CellFemaleHumansImmunoblottingInhibitor of Apoptosis ProteinsMaleMicrotubule-Associated ProteinsMiddle AgedMitomycinNeoplasm ProteinsNeoplasm Recurrence, LocalPredictive Value of TestsPrognosisSurvivinTreatment OutcomeUrinary Bladder NeoplasmsConceptsTransitional cell carcinomaCompletion of treatmentBacillus Calmette-GuerinUrinary survivin levelsSurvivin levelsTCC recurrenceCalmette-GuerinUrine survivinIntravesical treatmentIntravesical instillationCell carcinomaMitomycin CRecurrent transitional cell carcinomaPrognostic molecular markersHigher survivin levelsUrinary survivinPosttreatment valuesRecurrenceMonthsHigher likelihoodSurvivinRemissionUrineTreatmentInstillationUrinary interleukin-8 levels are elevated in subjects with transitional cell carcinoma
Sheryka E, Wheeler MA, Hausladen DA, Weiss RM. Urinary interleukin-8 levels are elevated in subjects with transitional cell carcinoma. Urology 2003, 62: 162-166. PMID: 12837459, DOI: 10.1016/s0090-4295(03)00134-1.Peer-Reviewed Original ResearchConceptsUrinary IL-8 levelsIL-8 levelsTransitional cell carcinomaBacille Calmette-GuérinIL-8Cell carcinomaCalmette-GuérinProstate cancerHealthy subjectsActive transitional cell carcinomaUrinary interleukin-8 levelsLow stage transitional cell carcinomaInterleukin-8 levelsBladder cancer cell linesBladder cancer cellsEnzyme-linked immunosorbentCancer cell linesIntravesical therapyInflammatory processInvasive tumorsAngiogenic factorsMitomycin CElevated levelsCancer cellsMitomycin C.
2001
Urine Detection of Survivin and Diagnosis of Bladder Cancer
Smith SD, Wheeler MA, Plescia J, Colberg JW, Weiss RM, Altieri DC. Urine Detection of Survivin and Diagnosis of Bladder Cancer. JAMA 2001, 285: 324-328. PMID: 11176843, DOI: 10.1001/jama.285.3.324.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBiomarkers, TumorBlotting, WesternFemaleHumansInhibitor of Apoptosis ProteinsMaleMicrotubule-Associated ProteinsMiddle AgedNeoplasm ProteinsNeoplasm Recurrence, LocalPrognosisProteinsReverse Transcriptase Polymerase Chain ReactionSensitivity and SpecificityStatistics, NonparametricSurvivinUrinary Bladder NeoplasmsUrogenital NeoplasmsUrologic DiseasesConceptsRecurrent bladder cancerUrinary tract diseaseBladder cancerUrine samplesTract diseaseHealthy volunteersSurvivin levelsProstate-specific antigen levelLow-grade bladder cancerPrognostic molecular markersNoninvasive diagnostic testTranscriptase-polymerase chain reactionCommon human cancersUrine survivinGenitourinary cancersProgression of cancerAggressive diseaseAntigen levelsCervical cancerUrology clinicPolymerase chain reactionUnfavorable outcomeCystoscopy resultsRT-PCR methodSurvivin detection
1999
Tumor Content of the Antiapoptosis Molecule Survivin and Recurrence of Bladder Cancer
Swana H, Grossman D, Anthony J, Weiss R, Altieri D. Tumor Content of the Antiapoptosis Molecule Survivin and Recurrence of Bladder Cancer. New England Journal Of Medicine 1999, 341: 452-453. PMID: 10438269, DOI: 10.1056/nejm199908053410614.Peer-Reviewed Original ResearchAgedApoptosisBiomarkers, TumorCarcinoma, Transitional CellDisease ProgressionFemaleHumansInhibitor of Apoptosis ProteinsMaleMicrotubule-Associated ProteinsMiddle AgedNeoplasm ProteinsNeoplasm Recurrence, LocalProteinsProto-Oncogene Proteins c-bcl-2SurvivinTumor Suppressor Protein p53Urinary Bladder Neoplasms