2002
Prostaglandin E2 Production and Cyclooxygenase-2 Induction in Human Urinary Tract Infections and Bladder Cancer
Wheeler MA, Hausladen DA, Yoon JH, Weiss RM. Prostaglandin E2 Production and Cyclooxygenase-2 Induction in Human Urinary Tract Infections and Bladder Cancer. Journal Of Urology 2002, 168: 1568-1573. PMID: 12352459, DOI: 10.1016/s0022-5347(05)64522-3.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBCG VaccineCyclooxygenase 1Cyclooxygenase 2DinoprostoneEnzyme InductionFemaleGene Expression Regulation, EnzymologicHumansIsoenzymesMaleMembrane ProteinsMiddle AgedProstaglandin-Endoperoxide SynthasesRNA, MessengerUreterUrinary BladderUrinary Bladder NeoplasmsUrinary Tract InfectionsUrogenital NeoplasmsUrotheliumConceptsUrinary prostaglandin E2 levelsUrinary tract infectionProstaglandin E2 levelsUrinary prostaglandin E2Tract infectionsBladder cancerProstaglandin E2 productionBCG treatmentCOX-2 mRNAUrogenital cancersE2 levelsUrine particulatesBladder muscleInflammatory processProstaglandin E2E2 productionBacillus Calmette-Guerin treatmentCOX-2 protein levelsCOX-2 protein expressionHuman urinary tract infectionsUrinary prostaglandin levelsCOX-2 expressionHuman bladder muscleBladder cancer casesCyclooxygenase-2 induction
2001
Urine Detection of Survivin and Diagnosis of Bladder Cancer
Smith SD, Wheeler MA, Plescia J, Colberg JW, Weiss RM, Altieri DC. Urine Detection of Survivin and Diagnosis of Bladder Cancer. JAMA 2001, 285: 324-328. PMID: 11176843, DOI: 10.1001/jama.285.3.324.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBiomarkers, TumorBlotting, WesternFemaleHumansInhibitor of Apoptosis ProteinsMaleMicrotubule-Associated ProteinsMiddle AgedNeoplasm ProteinsNeoplasm Recurrence, LocalPrognosisProteinsReverse Transcriptase Polymerase Chain ReactionSensitivity and SpecificityStatistics, NonparametricSurvivinUrinary Bladder NeoplasmsUrogenital NeoplasmsUrologic DiseasesConceptsRecurrent bladder cancerUrinary tract diseaseBladder cancerUrine samplesTract diseaseHealthy volunteersSurvivin levelsProstate-specific antigen levelLow-grade bladder cancerPrognostic molecular markersNoninvasive diagnostic testTranscriptase-polymerase chain reactionCommon human cancersUrine survivinGenitourinary cancersProgression of cancerAggressive diseaseAntigen levelsCervical cancerUrology clinicPolymerase chain reactionUnfavorable outcomeCystoscopy resultsRT-PCR methodSurvivin detection