2002
Prostaglandin E2 Production and Cyclooxygenase-2 Induction in Human Urinary Tract Infections and Bladder Cancer
Wheeler MA, Hausladen DA, Yoon JH, Weiss RM. Prostaglandin E2 Production and Cyclooxygenase-2 Induction in Human Urinary Tract Infections and Bladder Cancer. Journal Of Urology 2002, 168: 1568-1573. PMID: 12352459, DOI: 10.1016/s0022-5347(05)64522-3.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBCG VaccineCyclooxygenase 1Cyclooxygenase 2DinoprostoneEnzyme InductionFemaleGene Expression Regulation, EnzymologicHumansIsoenzymesMaleMembrane ProteinsMiddle AgedProstaglandin-Endoperoxide SynthasesRNA, MessengerUreterUrinary BladderUrinary Bladder NeoplasmsUrinary Tract InfectionsUrogenital NeoplasmsUrotheliumConceptsUrinary prostaglandin E2 levelsUrinary tract infectionProstaglandin E2 levelsUrinary prostaglandin E2Tract infectionsBladder cancerProstaglandin E2 productionBCG treatmentCOX-2 mRNAUrogenital cancersE2 levelsUrine particulatesBladder muscleInflammatory processProstaglandin E2E2 productionBacillus Calmette-Guerin treatmentCOX-2 protein levelsCOX-2 protein expressionHuman urinary tract infectionsUrinary prostaglandin levelsCOX-2 expressionHuman bladder muscleBladder cancer casesCyclooxygenase-2 induction
2001
Urine Detection of Survivin and Diagnosis of Bladder Cancer
Smith SD, Wheeler MA, Plescia J, Colberg JW, Weiss RM, Altieri DC. Urine Detection of Survivin and Diagnosis of Bladder Cancer. JAMA 2001, 285: 324-328. PMID: 11176843, DOI: 10.1001/jama.285.3.324.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBiomarkers, TumorBlotting, WesternFemaleHumansInhibitor of Apoptosis ProteinsMaleMicrotubule-Associated ProteinsMiddle AgedNeoplasm ProteinsNeoplasm Recurrence, LocalPrognosisProteinsReverse Transcriptase Polymerase Chain ReactionSensitivity and SpecificityStatistics, NonparametricSurvivinUrinary Bladder NeoplasmsUrogenital NeoplasmsUrologic DiseasesConceptsRecurrent bladder cancerUrinary tract diseaseBladder cancerUrine samplesTract diseaseHealthy volunteersSurvivin levelsProstate-specific antigen levelLow-grade bladder cancerPrognostic molecular markersNoninvasive diagnostic testTranscriptase-polymerase chain reactionCommon human cancersUrine survivinGenitourinary cancersProgression of cancerAggressive diseaseAntigen levelsCervical cancerUrology clinicPolymerase chain reactionUnfavorable outcomeCystoscopy resultsRT-PCR methodSurvivin detection
2000
Temporal changes of cytokines and nitric oxide products in urine from renal transplant patients
Smith S, Wheeler M, Lorber M, Weiss R. Temporal changes of cytokines and nitric oxide products in urine from renal transplant patients. Kidney International 2000, 58: 829-837. PMID: 10916108, DOI: 10.1046/j.1523-1755.2000.00232.x.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdultCreatinineCyclic GMPCytokinesFemaleFollow-Up StudiesGraft RejectionHumansInterleukin-10Interleukin-2Interleukin-6Interleukin-8Kidney Failure, ChronicKidney TransplantationMaleMiddle AgedNitratesNitric OxideNitritesPredictive Value of TestsTime FactorsTumor Necrosis Factor-alphaUrinary Tract InfectionsConceptsUrinary tract infectionRenal transplant patientsAcute rejectionTransplant patientsCyclic GMPIL-2Nitric oxideNitric oxide synthase activityAdditional urine specimensUrine cytokine levelsUrine nitrate levelsNitric oxide productsMonths of transplantationOxide synthase activityUrine nitrateSoluble interleukinCytokine levelsTract infectionsIL-10IL-6IL-8Tumor necrosisUrine specimensPatientsClinical diagnosis
1998
Detection of urinary tract infections by reduction of nitroblue tetrazolium Technical Note
Smith S, Wheeler M, Weiss R. Detection of urinary tract infections by reduction of nitroblue tetrazolium Technical Note. Kidney International 1998, 54: 1331-1336. PMID: 9767552, DOI: 10.1046/j.1523-1755.1998.00102.x.Peer-Reviewed Original ResearchConceptsUrinary tract infectionNitric oxide synthaseNegative predictive accuracyDismutase/catalaseNitrite dipstickTract infectionsPresence of UTINOS cofactorUrine pelletsInducible nitric oxide synthaseHigh negative predictive accuracyHigh positive predictive accuracyUrine screening testsUrine culture resultsNBT reductionInducible NOS activityLeukocyte esterase dipstickNitroblue tetrazolium reductionPositive predictive accuracyNOS inhibitorNOS activityOxide synthaseEarly predictorCulture resultsScreening test
1997
Improvement in Interstitial Cystitis Symptom Scores During Treatment With Oral L-Arginine
Smith S, Wheeler M, Foster H, Weiss R. Improvement in Interstitial Cystitis Symptom Scores During Treatment With Oral L-Arginine. Journal Of Urology 1997, 158: 703-708. DOI: 10.1016/s0022-5347(01)64297-6.Peer-Reviewed Original ResearchConceptsOral L-arginineL-arginineInterstitial cystitisInterstitial Cystitis Symptom ScoreNitric oxide synthase activityLower abdominal painInterstitial cystitis symptomsL-arginine treatmentOxide synthase activityNitric oxide synthaseSelf-controlled studyAbdominal painUrethral painUrinary frequencyCystitis symptomsSymptom scoresMethodsTen patientsOxide synthaseRelated symptomsImmunological responseNitric oxidePatientsSymptomsSignificant decreaseCystitisImprovement in Interstitial Cystitis Symptom Scores During Treatment With Oral L-Arginine
Smith S, Wheeler M, Foster H, Weiss R. Improvement in Interstitial Cystitis Symptom Scores During Treatment With Oral L-Arginine. Journal Of Urology 1997, 158: 703-708.. PMID: 9258064, DOI: 10.1097/00005392-199709000-00005.Peer-Reviewed Original ResearchConceptsOral L-arginineL-arginineInterstitial cystitisUrinary nitric oxide synthase activityInterstitial Cystitis Symptom ScoreOral L-arginine treatmentNitric oxide synthase activityLower abdominal painInterstitial cystitis symptomsMethods Ten patientsL-arginine treatmentOxide synthase activityNitric oxide synthaseSelf-controlled studyAbdominal painTEN patientsUrethral painUrinary frequencyCystitis symptomsSymptom scoresOxide synthaseRelated symptomsImmunological responseNitric oxidePatientsBacterial infection induces nitric oxide synthase in human neutrophils.
Wheeler MA, Smith SD, García-Cardeña G, Nathan CF, Weiss RM, Sessa WC. Bacterial infection induces nitric oxide synthase in human neutrophils. Journal Of Clinical Investigation 1997, 99: 110-116. PMID: 9011564, PMCID: PMC507774, DOI: 10.1172/jci119121.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnti-Bacterial AgentsArginineBacterial InfectionsBlotting, WesternCanavanineCell MembraneCitrullineFemaleGuanidinesHumansImmunohistochemistryIsoenzymesLeukocyte Common AntigensMaleMiddle AgedNeutrophilsNG-Nitroarginine Methyl EsterNitric Oxide SynthaseNitroarginineOmega-N-MethylarginineOrnithinePolymerase Chain ReactionRNA, MessengerSulfonamidesThioureaTrifluoperazineUrinary Tract InfectionsConceptsInducible nitric oxide synthaseUrinary tract infectionNitric oxide synthaseNitric oxide synthase activityTract infectionsOxide synthase activityOxide synthaseInducible nitric oxide synthase activityNitric oxide synthase proteinNitric oxide synthase isoformsInduces nitric oxide synthaseMajor nitric oxide synthase isoformHuman inflammatory cellsHuman inducible nitric oxide synthaseExtended elevationInflammatory cellsProinflammatory functionsAntibiotic treatmentInflammatory processSynthase activityImmunocytochemical evidenceHuman neutrophilsInfectionCalcium independentSynthase isoforms
1996
Nitric oxide synthase induction with renal transplant rejection or infection
Smith S, Wheeler M, Zhang R, Weiss E, Lorber M, Sessa W, Weiss R. Nitric oxide synthase induction with renal transplant rejection or infection. Kidney International 1996, 50: 2088-2093. PMID: 8943494, DOI: 10.1038/ki.1996.533.Peer-Reviewed Original ResearchConceptsUrinary tract infectionRenal transplant patientsNitric oxide synthaseCyclic GMP levelsTransplant patientsTract infectionsNOS activityPost-renal transplantation patientsGMP levelsInducible nitric oxide synthaseNitric oxideRenal allograft rejectionRenal transplant rejectionNitric oxide synthase inductionInducible NOS (iNOS) mRNAUrine of patientsRenal transplantationTransplantation patientsAllograft rejectionTransplant rejectionInducible NOSOxide synthaseNOS mRNAPatientsSynthase inductionUrinary Nitric Oxide Synthase Activity and Cyclic GMP Levels are Decreased with Interstitial Cystitis and Increased with Urinary Tract Infections
Smith S, Wheeler M, Foster H, Weiss R. Urinary Nitric Oxide Synthase Activity and Cyclic GMP Levels are Decreased with Interstitial Cystitis and Increased with Urinary Tract Infections. Journal Of Urology 1996, 155: 1432-1435. PMID: 8632605, DOI: 10.1016/s0022-5347(01)66301-8.Peer-Reviewed Original ResearchConceptsUrinary tract infectionCyclic GMP levelsUrinary nitric oxide synthase activityNitric oxide synthase activityInterstitial cystitisOxide synthase activityFemale patientsNOS activityTract infectionsGMP levelsFemale controlsFemale urinary tract infectionCyclic GMP/Certain disease processesIC patientsImmunologic responseUrinary tractSynthase activityDisease processL-argininePatientsNitric oxideL-citrullineGuanylyl cyclaseCyclic GMP
1990
Variable Expression of 5α-Reductase Deficiency: Presentation with Male Phenotype in a Child of Greek Origin*
CARPENTER T, IMPERATO-MCGINLEY J, BOULWARE S, WEISS R, SHACKLETON C, GRIFFIN J, WILSON J. Variable Expression of 5α-Reductase Deficiency: Presentation with Male Phenotype in a Child of Greek Origin*. The Journal Of Clinical Endocrinology & Metabolism 1990, 71: 318-322. PMID: 2143199, DOI: 10.1210/jcem-71-2-318.Peer-Reviewed Original Research3-Oxo-5-alpha-Steroid 4-DehydrogenaseAdultAndrostenedioneBiopsyChorionic GonadotropinDehydroepiandrosteroneDihydrotestosteroneFemaleFibroblastsFollicle Stimulating HormoneGreeceHumansHypospadiasInfantKaryotypingLuteinizing HormoneMalePhenotypeReceptors, AndrogenReference ValuesSkinTestosteroneUnited StatesMalignant Rhabdoid Tumor of the Kidney in an Adult
Lowe W, Weiss R, Todd M, True L. Malignant Rhabdoid Tumor of the Kidney in an Adult. Journal Of Urology 1990, 143: 110-111. PMID: 2152948, DOI: 10.1016/s0022-5347(17)39882-8.Peer-Reviewed Original Research
1982
Fetal urinary tract obstruction: What is the role of surgical intervention in utero?
Berkowitz R, Glickman M, Smith G, Siegel N, Weiss R, Mahoney M, Hobbins J. Fetal urinary tract obstruction: What is the role of surgical intervention in utero? American Journal Of Obstetrics And Gynecology 1982, 144: 367-375. PMID: 7124856, DOI: 10.1016/0002-9378(82)90239-3.Commentaries, Editorials and LettersVenography of the Undescended Testis
Weiss R, Glickman M. Venography of the Undescended Testis. Urologic Clinics Of North America 1982, 9: 387-395. PMID: 6128822, DOI: 10.1016/s0094-0143(21)01353-7.Peer-Reviewed Original Research
1980
Localization and Management of Nonpalpable Undescended Testes
Weiss R, Glickman M. Localization and Management of Nonpalpable Undescended Testes. Surgical Clinics Of North America 1980, 60: 1253-1263. PMID: 6107996, DOI: 10.1016/s0039-6109(16)42248-6.Commentaries, Editorials and Letters
1979
Clinical Implications of Gonadal Venography in the Management of the Non-Palpable Undescended Testis
Weiss R, Glickman M, Lytton B. Clinical Implications of Gonadal Venography in the Management of the Non-Palpable Undescended Testis. Journal Of Urology 1979, 121: 745-749. PMID: 37348, DOI: 10.1016/s0022-5347(17)56977-3.Peer-Reviewed Original Research
1976
Urologic Complications of Inflammatory Bowel Disease
Shield D, Lytton B, Weiss R, Schiff M. Urologic Complications of Inflammatory Bowel Disease. Journal Of Urology 1976, 115: 701-706. PMID: 940206, DOI: 10.1016/s0022-5347(17)59341-6.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseBowel diseaseUrologic complicationsPrimary bowel diseaseUrinary tract complicationsLong-term managementEnterovesical fistulaUrologic evaluationGastrointestinal disordersUreteral obstructionComplicationsDiseaseUrinary calculiPatientsCommon problemFistulaObstructionSymptoms
1975
Palliative Urinary Diversion for Pelvic Malignancy
Brin E, Schiff M, Weiss R. Palliative Urinary Diversion for Pelvic Malignancy. Journal Of Urology 1975, 113: 619-622. PMID: 47918, DOI: 10.1016/s0022-5347(17)59536-1.Peer-Reviewed Original Research
1974
Hemorrhagic radiation cystitis Treatment
McGuire E, Weiss R, Schiff M, Lytton B. Hemorrhagic radiation cystitis Treatment. Urology 1974, 3: 204-208. PMID: 4812667, DOI: 10.1016/s0090-4295(74)80016-6.Peer-Reviewed Original Research
1973
Leiomyoma of the Female Urethra
Shield D, Weiss R. Leiomyoma of the Female Urethra. Journal Of Urology 1973, 109: 430-431. PMID: 4692377, DOI: 10.1016/s0022-5347(17)60443-9.Peer-Reviewed Original Research
1971
Staghorn Calculi in Solitary Kidneys
Libertino J, Newman H, Lytton B, Weiss R. Staghorn Calculi in Solitary Kidneys. Journal Of Urology 1971, 105: 753-757. PMID: 5091702, DOI: 10.1016/s0022-5347(17)61623-9.Peer-Reviewed Original Research