2006
Age Related Changes in the Functional, Biochemical and Molecular Properties of α1-Adrenoceptors in the Rat Genitourinary Tract
Yono M, Foster HE, Weiss RM, Latifpour J. Age Related Changes in the Functional, Biochemical and Molecular Properties of α1-Adrenoceptors in the Rat Genitourinary Tract. Journal Of Urology 2006, 176: 1214-1219. PMID: 16890728, DOI: 10.1016/j.juro.2006.04.038.Peer-Reviewed Original ResearchConceptsRat genitourinary tractLower urinary tract symptomsUrinary tract symptomsBenign prostatic hyperplasiaAdrenoceptor antagonistGenitourinary tractTract symptomsBladder baseProstatic hyperplasiaDorsolateral prostateYoung ratsIsolated muscle bathMaximum contractile responseTranscriptase-polymerase chain reaction techniqueRadioligand receptor bindingReverse transcriptase-polymerase chain reaction techniqueSignificant age-dependent differencesAge-dependent differencesAge related changesHigher body weightAge related differencesContractile responseAdrenoceptor densityAdrenoceptor subtypesBladder dome
1978
Ureteral function
Weiss R. Ureteral function. Urology 1978, 12: 114-133. PMID: 211688, DOI: 10.1016/0090-4295(78)90321-7.Peer-Reviewed Original ResearchConceptsUreteral functionBeta-adrenergic receptor mechanismVesico-ureteral refluxElectrical activitySmooth muscle relaxationUreteral peristaltic activityBeta-adrenergic receptorsUrinary collecting systemExcitation-contraction couplingAge-dependent factorsUreteral contractionsUreteral lengthUreteral activityIntracellular storage sitesMuscle relaxationReceptor mechanismsPeristaltic activityAction potentialsUreterPacemaker siteProximal portionCollecting systemContractile proteinsCell membraneContractile process