2000
Expression and localization of basic fibroblast growth factor in diabetic rat prostate
Wang Z, Ikeda K, Wada Y, Foster H, Weiss R, Latifpour J. Expression and localization of basic fibroblast growth factor in diabetic rat prostate. BJU International 2000, 85: 945-952. PMID: 10792180, DOI: 10.1046/j.1464-410x.2000.00597.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBlotting, WesternDiabetes Mellitus, ExperimentalFibroblast Growth Factor 2ImmunohistochemistryMaleProstateRatsRats, Sprague-DawleyConceptsBenign prostatic hyperplasiaDiabetic ratsExpression of FGF2Testosterone levelsRat prostateLow serum testosterone levelsHuman benign prostatic hyperplasiaAge-matched control ratsWestern blottingSerum testosterone levelsPolymerase chain reaction studiesDiabetic rat prostateReverse transcriptase-polymerase chain reaction studiesGroups of ratsBasic fibroblast growth factorImmuno-histochemical studyFibroblast growth factor-2Fibroblast growth factorProstatic sectionsFGF-2 mRNAGrowth factor 2Smaller prostatesProstatic hyperplasiaProstatic sizeProstatic growth
1999
INDUCIBLE NITRIC OXIDE SYNTHASE WITH TRANSITIONAL CELL CARCINOMA OF THE BLADDER
SWANA H, SMITH S, PERROTTA P, SAITO N, WHEELER M, WEISS R. INDUCIBLE NITRIC OXIDE SYNTHASE WITH TRANSITIONAL CELL CARCINOMA OF THE BLADDER. Journal Of Urology 1999, 161: 630-634. PMID: 9915473, DOI: 10.1016/s0022-5347(01)61985-2.Peer-Reviewed Original ResearchMeSH KeywordsCarcinoma, Transitional CellHumansImmunohistochemistryNitric Oxide SynthaseReverse Transcriptase Polymerase Chain ReactionUrinary Bladder NeoplasmsConceptsTransitional cell carcinomaNitric oxide synthaseInducible nitric oxide synthaseReverse transcriptase-polymerase chain reactionBladder tissueCell carcinomaInflammatory cellsNOS activityOxide synthaseNitric oxideTumor cellsGrades of TCCDistribution of iNOSImmunoreactive iNOS proteinHuman bladder tumorsTranscriptase-polymerase chain reactionIndividual tumor cellsControl bladder tissueCytostatic mediatorsINOS antibodyTumor immunoreactivityWestern blot analysisBladder tumorsTumor gradeImmune stimulation
1998
CHARACTERIZATION, LOCALIZATION AND DISTRIBUTION OF alpha1 ADRENOCEPTOR SUBTYPE IN MALE RABBIT URETHRA
NISHI K, LATIFPOUR J, SAITO M, FOSTER H, YOSHIDA M, WEISS R. CHARACTERIZATION, LOCALIZATION AND DISTRIBUTION OF alpha1 ADRENOCEPTOR SUBTYPE IN MALE RABBIT URETHRA. Journal Of Urology 1998, 160: 196-205. PMID: 9628650, DOI: 10.1016/s0022-5347(01)63090-8.Peer-Reviewed Original ResearchConceptsAlpha1 adrenoceptorsRabbit urethraMale rabbit urethraSelective alpha1-adrenoceptor antagonistAnti-alpha smooth muscle actinAlpha1-adrenoceptor antagonistRabbit urethral smooth muscleUrethral smooth muscleRadioligand receptor bindingSmooth muscle actinSmooth muscle fibersLight microscopic autoradiographySingle high-affinity binding siteAdrenoceptor antagonistBMY 7378Distal urethraWB 4101Immunohistochemical studyPharmacological characterizationSmooth musclePharmacological profileAdrenoceptorsUrethraMuscle actinHigh-affinity binding sites
1997
Bacterial infection induces nitric oxide synthase in human neutrophils.
Wheeler MA, Smith SD, García-Cardeña G, Nathan CF, Weiss RM, Sessa WC. Bacterial infection induces nitric oxide synthase in human neutrophils. Journal Of Clinical Investigation 1997, 99: 110-116. PMID: 9011564, PMCID: PMC507774, DOI: 10.1172/jci119121.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnti-Bacterial AgentsArginineBacterial InfectionsBlotting, WesternCanavanineCell MembraneCitrullineFemaleGuanidinesHumansImmunohistochemistryIsoenzymesLeukocyte Common AntigensMaleMiddle AgedNeutrophilsNG-Nitroarginine Methyl EsterNitric Oxide SynthaseNitroarginineOmega-N-MethylarginineOrnithinePolymerase Chain ReactionRNA, MessengerSulfonamidesThioureaTrifluoperazineUrinary Tract InfectionsConceptsInducible nitric oxide synthaseUrinary tract infectionNitric oxide synthaseNitric oxide synthase activityTract infectionsOxide synthase activityOxide synthaseInducible nitric oxide synthase activityNitric oxide synthase proteinNitric oxide synthase isoformsInduces nitric oxide synthaseMajor nitric oxide synthase isoformHuman inflammatory cellsHuman inducible nitric oxide synthaseExtended elevationInflammatory cellsProinflammatory functionsAntibiotic treatmentInflammatory processSynthase activityImmunocytochemical evidenceHuman neutrophilsInfectionCalcium independentSynthase isoforms