2008
Prostate expression of endothelins and their receptors in rat growth
Wada Y, Takahashi W, Latifpour J, Weiss RM, Matsumoto K, Matsui K, Yamada, Imamura T. Prostate expression of endothelins and their receptors in rat growth. Reproduction Fertility And Development 2008, 20: 750-759. PMID: 18842177, DOI: 10.1071/rd08052.Peer-Reviewed Original ResearchConceptsET-1Receptors ETAProstate growthProstate lobesET-3Role of ETAVentral prostate lobeReverse transcription-polymerase chain reactionTranscription-polymerase chain reactionMultiplex reverse transcription-polymerase chain reactionMRNA expression levelsProstate expressionEndothelinMitogenic effectProstate cellsMRNA expressionMembrane particulatesHigh expressionMonthsWeeksEnzyme 1Chain reactionExpression levelsRat growthRats
2005
Effect of insulin treatment on tissue size of the genitourinary tract in BB rats with spontaneously developed and streptozotocin-induced diabetes
Yono M, Pouresmail M, Takahashi W, Flanagan JF, Weiss RM, Latifpour J. Effect of insulin treatment on tissue size of the genitourinary tract in BB rats with spontaneously developed and streptozotocin-induced diabetes. Naunyn-Schmiedeberg's Archives Of Pharmacology 2005, 372: 251-255. PMID: 16235050, DOI: 10.1007/s00210-005-0010-9.Peer-Reviewed Original ResearchConceptsSTZ-induced diabetesBB ratsSpontaneous diabetesGenitourinary tractInsulin treatmentDiabetes-resistant BB ratsDiabetes-prone BB ratsHyperglycemic diabetic ratsStreptozotocin-induced diabetesSerum testosterone levelsSignificant decreaseGroups of ratsEuglycemic diabeticsEuglycemic groupTissue weight changesBladder weightDiabetic ratsSuboptimal doseAdrenal glandHyperglycemic groupDiabetic studyTestosterone levelsDiabetesControl groupVentral prostate
2002
The effect of castration on endothelins, their receptors and endothelin converting enzyme in rat prostate
Takahashi W, Afiatpour P, Foster H, Ikeda K, Wada Y, Weiss RM, Latifpour J. The effect of castration on endothelins, their receptors and endothelin converting enzyme in rat prostate. Naunyn-Schmiedeberg's Archives Of Pharmacology 2002, 366: 166-176. PMID: 12122504, DOI: 10.1007/s00210-002-0575-5.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAspartic Acid EndopeptidasesAutoradiographyDiabetes Mellitus, ExperimentalDNA PrimersEndothelin-1Endothelin-3Endothelin-Converting EnzymesGene ExpressionMaleMetalloendopeptidasesMicroscopyOrchiectomyOrgan SizeProstateProtein BindingRadioligand AssayRatsRats, Sprague-DawleyReceptor, Endothelin AReceptor, Endothelin BReceptors, EndothelinReverse Transcriptase Polymerase Chain ReactionRNA, MessengerConceptsReceptor subtype mRNAsET receptor subtypesSerum testosterone levelsET receptorsRat prostateEffects of castrationReceptor subtypesSubtype mRNAsDorsolateral regionTestosterone levelsET-1Three-month-old SpraguePharmacological propertiesDiabetes-induced reductionET receptor systemET-3 mRNAETB receptor subtypesPost-operative dayReverse transcription-polymerase chain reactionVentral regionECE-1 mRNATranscription-polymerase chain reactionLight microscopy autoradiographyEnzyme-1 mRNAMultiplex reverse transcription-polymerase chain reaction
2000
Expression of endothelin receptor subtypes and their messenger RNAs in diabetic rat prostate: Effect of insulin treatment
Saito M, Wado Y, Ikeda K, Wang Z, Foster H, Smith S, Weiss R, Latifpour J. Expression of endothelin receptor subtypes and their messenger RNAs in diabetic rat prostate: Effect of insulin treatment. Molecular And Cellular Biochemistry 2000, 210: 1-11. PMID: 10976752, DOI: 10.1023/a:1007041909477.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAutoradiographyBlood GlucoseBody WeightDiabetes Mellitus, ExperimentalEndothelin Receptor AntagonistsEndothelin-1InsulinIodine RadioisotopesMaleOrgan SizeProstateProtein IsoformsRadioligand AssayRandom AllocationRatsRats, Sprague-DawleyReceptor, Endothelin AReceptor, Endothelin BReceptors, EndothelinReverse Transcriptase Polymerase Chain ReactionRNA, MessengerTestosteroneUp-RegulationConceptsInduction of diabetesET receptorsReverse transcription-polymerase chain reactionRat prostateInsulin treatmentDiabetic animalsReceptor subtypesDiabetes-induced upregulationET receptor densityEndothelin receptor subtypesET receptor subtypesSTZ-injected ratsSerum testosterone levelsRadioligand receptor bindingDiabetic rat prostateTranscription-polymerase chain reactionDiabetic ratsETB receptorsSmaller prostatesEndothelin receptorsProstatic stromaTestosterone levelsReceptor densityPharmacological profileAutoradiographic study
1999
Developmental aspects of endothelin receptors in rabbit lower urinary tract
Saito M, Latifpour J, Weiss R. Developmental aspects of endothelin receptors in rabbit lower urinary tract. Neurourology And Urodynamics 1999, 19: 71-85. PMID: 10602249, DOI: 10.1002/(sici)1520-6777(2000)19:1<71::aid-nau8>3.0.co;2-9.Peer-Reviewed Original ResearchConceptsLower urinary tractRabbit lower urinary tractEndothelin receptorsUrinary tractBladder baseBladder domeMale rabbitsEndothelin receptor subtypesAge-related alterationsOld male rabbitsET receptorsReceptor subtypesPharmacological characterizationPharmacological profileAged rabbitsSubtype specificityReceptorsTractDevelopment-related changesSimilar proportionsWeeksReceptor compoundsUrethraRabbitsRank orderEffects of insulin treatment on diabetes‐induced alterations in endothelin receptors in rat ureter
Saito M, Weiss R, Latifpour J. Effects of insulin treatment on diabetes‐induced alterations in endothelin receptors in rat ureter. International Journal Of Urology 1999, 6: 361-368. PMID: 10445306, DOI: 10.1046/j.1442-2042.1999.00074.x.Peer-Reviewed Original Research
1996
Effect of experimental diabetes on rat prostate endothelin receptors
Saito M, Nishi K, Foster H, Weiss R, Latifpour J. Effect of experimental diabetes on rat prostate endothelin receptors. European Journal Of Pharmacology 1996, 310: 197-200. PMID: 8884217, DOI: 10.1016/0014-2999(96)00422-0.Peer-Reviewed Original Research
1994
Reversibility of Diabetes- and Diuresis-Induced Alterations in Rat Bladder Dome Muscarinic Receptors
Fukomoto Y, Yoshida M, Weiss R, Latifpour J. Reversibility of Diabetes- and Diuresis-Induced Alterations in Rat Bladder Dome Muscarinic Receptors. Diabetes 1994, 43: 819-826. PMID: 8194669, DOI: 10.2337/diab.43.6.819.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBinding, CompetitiveBody WeightCell MembraneDiabetes Mellitus, ExperimentalDiaminesDiuresisDrinking BehaviorInsulinKineticsMaleMyocardiumOrgan SizeParasympatholyticsPiperidinesPirenzepineProstateQuinuclidinyl BenzilateRatsRats, Sprague-DawleyReceptors, MuscarinicSucroseTestosteroneUp-RegulationUrinary BladderConceptsAge-matched control ratsMuscarinic receptorsRat bladder domeBladder domeDiuretic ratsDiabetic ratsControl ratsSTZ-induced diabetic ratsInsulin-treated diabetic ratsDiabetes-induced upregulationEarly insulin treatmentSucrose-fed ratsGroups of ratsIncreased water intakeBladder hypertrophyUrine outputInsulin treatmentRadioligand receptorRatsDiabetesDiuretic stateReceptorsWater intakeWeeksUpregulation
1993
Age-related changes in Ca2+ channel antagonist receptors in rabbit lower urinary tract
Yoshida M, Latifpour J, Weiss R. Age-related changes in Ca2+ channel antagonist receptors in rabbit lower urinary tract. European Journal Of Pharmacology 1993, 232: 159-167. PMID: 8385616, DOI: 10.1016/0014-2999(93)90769-e.Peer-Reviewed Original ResearchConceptsLower urinary tractBladder baseBladder domeUrinary tractChannel antagonistsRabbit lower urinary tractBay K 8644Channel antagonist receptorsAge-dependent changesDensity of Ca2Age-related changesAntagonist binding sitesReceptor densityPharmacological profileAntagonist receptorsRabbit urethraUrethraAge groupsBmax valuesDays rabbitsAntagonistTractWeeksRank orderBinding sites
1992
Age-related changes in calcium antagonist receptors in rabbit ureter.
Yoshida M, Latifpour J, Weiss R. Age-related changes in calcium antagonist receptors in rabbit ureter. Neonatology 1992, 18: 100-7. PMID: 1483355, DOI: 10.1159/000480603.Peer-Reviewed Original Research
1991
Beta adrenergic receptor alterations in diabetic rat prostate: Effects of insulin and dietary myoinositol
Gousse A, Yoshida M, Weiss R, Latifpour J. Beta adrenergic receptor alterations in diabetic rat prostate: Effects of insulin and dietary myoinositol. The Prostate 1991, 19: 121-131. PMID: 1681523, DOI: 10.1002/pros.2990190205.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAnimalsBlood GlucoseBody WeightDiabetes Mellitus, ExperimentalDihydroalprenololDose-Response Relationship, DrugDrinkingInositolInsulinIsoproterenolMaleOrgan SizePropanolaminesPropranololProstateRadioligand AssayRatsRats, Inbred StrainsReceptors, Adrenergic, betaStreptozocinUrinationConceptsBeta-adrenergic receptorsAdrenergic receptorsInsulin levelsRadioligand receptor binding techniquesSelective beta-adrenergic antagonistsHigh blood glucose levelsLower serum insulin levelsAdrenergic receptor alterationsInduction of diabetesInsulin-treated diabeticsSerum insulin levelsBeta-adrenergic receptor alterationsAutonomic nervous systemBlood glucose levelsBeta-adrenergic antagonistsDiabetic rat prostateGroups of ratsReceptor binding techniquesEffect of insulinMale reproductive systemHigh water intakeDietary myoinositolDiabetes mellitusUrine outputDiabetic rats
1989
Effects of experimental diabetes on biochemical and functional characteristics of bladder muscarinic receptors.
Latifpour J, Gousse A, Kondo S, Morita T, Weiss R. Effects of experimental diabetes on biochemical and functional characteristics of bladder muscarinic receptors. Journal Of Pharmacology And Experimental Therapeutics 1989, 248: 81-8. PMID: 2913290.Peer-Reviewed Original ResearchConceptsMuscarinic receptorsBladder domeDiabetic animalsMuscarinic agonistsExperimental diabetesRat bladder smooth muscleED50 valuesHigher serum glucose levelsBladder muscarinic receptorsLarger contractile responsesMuscarinic receptor propertiesAF-DX 116Serum insulin levelsSerum glucose levelsBladder smooth muscleM2 muscarinic receptorsAge-matched controlsLower body weightReceptor binding studiesBladder dysfunctionContractile responseCommon complicationDiabetes mellitusPeripheral neuropathyUrine output