Riboswitches: Regulators of modern and ancient metabolism
Kim J, Breaker R. Riboswitches: Regulators of modern and ancient metabolism. The Biochemist 2006, 28: 11-15. DOI: 10.1042/bio02802011.Peer-Reviewed Original ResearchComplex biochemical pathwaysPrimitive life formsNucleic acid biochemistryAncient metabolismPrimitive organismsModern cellsLife formsStructured RNAsBiochemical pathwaysBiological processesEfficient enzymeRNARecent findingsMolecular sensorsSpecific receptorsSuch moleculesRiboswitchOrganismsRegulatorEnormous potentialEnzymePathwayBiochemistryMetabolismCellsGenetic control by riboswitches and ribozymes
Breaker R. Genetic control by riboswitches and ribozymes. The FASEB Journal 2006, 20: a455-a456. DOI: 10.1096/fasebj.20.4.a455-d.Peer-Reviewed Original ResearchGenetic switchGene expressionAptamer domainBacterial speciesCertain messenger RNAsControl gene expressionMessenger RNA stabilityNon-coding regionsComplex genetic elementsSelf-cleaving ribozymesRiboswitch classesReceptor-ligand interactionsTranscription elongationTranslation initiationRNA stabilityRNA transcriptionRiboswitchAllosteric changesGenetic controlGenetic elementsRNA structureMessenger RNATarget metabolitesRNARecent findings