2017
Single-cell cytokine profiling of tumor-infiltrating T cells to measure patient responses to anti-PD-1 therapy.
Mackay S, Flynn B, Morse K, Paczkowski P, Bacchiocchi A, Fan R, Halaban R, Zhou J. Single-cell cytokine profiling of tumor-infiltrating T cells to measure patient responses to anti-PD-1 therapy. Journal Of Clinical Oncology 2017, 35: 49-49. DOI: 10.1200/jco.2017.35.7_suppl.49.Peer-Reviewed Original ResearchTumor-infiltrating T lymphocytesAnti-PD-1 therapyClinical outcomesCytokine profilingAnti-tumor T cell functionAnti-tumor T cell immunityTumor-infiltrating T cellsMIP-1 αAnti-tumor immunityT cell immunityResponse of patientsT cell functionCell immunityCheckpoint immunotherapyMelanoma patientsIL-8Metastatic melanomaCancer patientsTIL functionTIL analysisPatient responseT cellsT lymphocytesGranzyme BImmune function
2016
Cellular Immunophenotyping: Industrial Technologies and Emerging Tools
Brower K, Fan R. Cellular Immunophenotyping: Industrial Technologies and Emerging Tools. 2016, 57-74. DOI: 10.1002/9783527801312.ch3.Peer-Reviewed Original ResearchCellular immune phenotypeHeterogeneous immune cellsImmune cell phenotypingPatient's immune statusDifferent patient cohortsImmune effector functionsDrug efficacy testingCellular immunityImmune statusPatient cohortImmune cellsImmune phenotypePatient responseEffector functionsDisease prognosisClinical settingCell phenotypingEfficacy testingGold standardCell populationsEffector moleculesImmunitySurface marker detectionPrognosisCohort