2024
Pragmaticism in Cancer Clinical Trials.
Sankar K, Redman M, Dragnev K, Henick B, Iams W, Blanke C, Herbst R, Gray J, Reckamp K. Pragmaticism in Cancer Clinical Trials. American Society Of Clinical Oncology Educational Book 2024, 44: e100040. PMID: 38771997, DOI: 10.1200/edbk_100040.Peer-Reviewed Original ResearchMeSH KeywordsClinical Trials as TopicHumansMedical OncologyNeoplasmsPragmatic Clinical Trials as TopicResearch DesignConceptsCancer clinical trialsTraditional explanatory trialsCancer mortality ratesPatient care scenariosGoal of improving patient outcomesPragmatic trial designTrial designRepresentative patient populationPragmatic trialIntervention effectsIntervention efficacyCare scenariosExplanatory trialsTrial generalizabilityPragmatic designPatient outcomesClinical trialsReal-world practiceOncologyEscalating costsCancer clinical trial designPatient populationMortality rateDuration of trialsOncology research
2022
Electronic Nicotine Delivery Systems: An Updated Policy Statement From the American Association for Cancer Research and the American Society of Clinical Oncology
Herbst RS, Hatsukami D, Acton D, Giuliani M, Moushey A, Phillips J, Sherwood S, Toll BA, Viswanath K, Warren NJH, Warren GW, Alberg AJ. Electronic Nicotine Delivery Systems: An Updated Policy Statement From the American Association for Cancer Research and the American Society of Clinical Oncology. Journal Of Clinical Oncology 2022, 40: 4144-4155. PMID: 36287017, DOI: 10.1200/jco.22.01749.Peer-Reviewed Original ResearchConceptsElectronic nicotine delivery systemsTobacco useENDS useCombustible tobaccoLong-term health risksEvidence-based treatmentsSurgeon General's ReportPublic healthNicotine delivery systemsTobacco-related disparitiesCombustible tobacco useBlood pressureSmoking cessationTobacco cessationCancer incidenceSmoking relapseClinical OncologyEpidemiological studiesImmune systemPotential efficacyE-cigarettesBrain developmentCancer developmentTobacco productsLongitudinal studyElectronic Nicotine Delivery Systems: An Updated Policy Statement from the American Association for Cancer Research and the American Society of Clinical Oncology
Herbst RS, Hatsukami D, Acton D, Giuliani M, Moushey A, Phillips J, Sherwood S, Toll BA, Viswanath K, Warren NJH, Warren GW, Alberg AJ. Electronic Nicotine Delivery Systems: An Updated Policy Statement from the American Association for Cancer Research and the American Society of Clinical Oncology. Clinical Cancer Research 2022, 28: of1-of10. PMID: 36287033, DOI: 10.1158/1078-0432.ccr-22-2429.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultElectronic Nicotine Delivery SystemsHumansMedical OncologyNeoplasmsNicotinePolicySmoking CessationUnited StatesConceptsElectronic nicotine delivery systemsTobacco useENDS useCombustible tobaccoLong-term health risksEvidence-based treatmentsSurgeon General's ReportPublic healthNicotine delivery systemsTobacco-related disparitiesCombustible tobacco useBlood pressureSmoking cessationTobacco cessationCancer incidenceSmoking relapseClinical OncologyEpidemiological studiesImmune systemPotential efficacyE-cigarettesBrain developmentCancer developmentTobacco productsLongitudinal studyESMO expert consensus statements on the management of EGFR mutant non-small-cell lung cancer
Passaro A, Leighl N, Blackhall F, Popat S, Kerr K, Ahn M, Arcila M, Arrieta O, Planchard D, de Marinis F, Dingemans A, Dziadziuszko R, Faivre-Finn C, Feldman J, Felip E, Curigliano G, Herbst R, Jänne P, John T, Mitsudomi T, Mok T, Normanno N, Paz-Ares L, Ramalingam S, Sequist L, Vansteenkiste J, Wistuba I, Wolf J, Wu Y, Yang S, Yang J, Yatabe Y, Pentheroudakis G, Peters S. ESMO expert consensus statements on the management of EGFR mutant non-small-cell lung cancer. Annals Of Oncology 2022, 33: 466-487. PMID: 35176458, DOI: 10.1016/j.annonc.2022.02.003.Peer-Reviewed Original ResearchMeSH KeywordsCarcinoma, Non-Small-Cell LungConsensusErbB ReceptorsHumansLung NeoplasmsMedical OncologyConceptsCell lung cancerLung cancerESMO Clinical Practice GuidelinesManagement of EGFRClinical practice guidelinesExpert consensus statementClinical trial designSummary of evidenceEpidermal growth factor receptorGrowth factor receptorAdvanced diseaseMetastatic diseaseMedical oncologyConsensus statementMultidisciplinary panelPractice guidelinesConsensus recommendationsTrial designExpert panel discussionAvailable evidenceEuropean SocietyFactor receptorCancerExpert panelBiomarker analysis
2019
Challenges and approaches to implementing master/basket trials in oncology
Burd A, Schilsky RL, Byrd JC, Levine RL, Papadimitrakopoulou VA, Herbst RS, Redman MW, Druker BJ, Gandara DR. Challenges and approaches to implementing master/basket trials in oncology. Blood Advances 2019, 3: 2237-2243. PMID: 31337605, PMCID: PMC6650731, DOI: 10.1182/bloodadvances.2019031229.Peer-Reviewed Original ResearchMeSH KeywordsClinical Decision-MakingClinical Trials as TopicDisease ManagementHumansMedical OncologyNeoplasmsPrecision MedicineResearch DesignConceptsBasket trialsClinical trial designHealth care providersDifferent tumor typesTherapeutic optionsImmunologic reactionsCare providersDrug development effortsTrial designTumor typesPatientsMost cancersClinical researchNew therapeuticsCancer communityTherapy todayMedical institutionsCancerCancer researchTrialsRare mutationsEpigenetic changesHistologyOncologyAppetite
2018
Treatment of Advanced Non–Small Cell Lung Cancer in 2018
Doroshow DB, Herbst RS. Treatment of Advanced Non–Small Cell Lung Cancer in 2018. JAMA Oncology 2018, 4: 569-570. PMID: 29494728, DOI: 10.1001/jamaoncol.2017.5190.Peer-Reviewed Original Research
2016
Smoking Cessation, Version 1.2016, NCCN Clinical Practice Guidelines in Oncology.
Shields PG, Herbst RS, Arenberg D, Benowitz NL, Bierut L, Luckart JB, Cinciripini P, Collins B, David S, Davis J, Hitsman B, Hyland A, Lang M, Leischow S, Park ER, Purcell WT, Selzle J, Silber A, Spencer S, Tanvetyanon T, Tiep B, Tindle HA, Tucker-Seeley R, Urbanic J, Hooper MW, Weksler B, Whitlock CW, Wood DE, Burns J, Scavone J. Smoking Cessation, Version 1.2016, NCCN Clinical Practice Guidelines in Oncology. Journal Of The National Comprehensive Cancer Network 2016, 14: 1430-1468. PMID: 27799513, DOI: 10.6004/jnccn.2016.0152.Peer-Reviewed Original ResearchConceptsSmoking cessationNCCN Clinical Practice GuidelinesClinical practice guidelinesEvidence-based standardsCancer treatment efficacyNCCN guidelinesOverall survivalCigarette smokingOncology carePharmacologic interventionsCancer deathPractice guidelinesTreatment efficacyCessationSmokingPatientsCancerCareGuidelinesOncologyResearch Priorities, Measures, and Recommendations for Assessment of Tobacco Use in Clinical Cancer Research
Land SR, Toll BA, Moinpour CM, Mitchell SA, Ostroff JS, Hatsukami DK, Duffy SA, Gritz ER, Rigotti NA, Brandon TH, Prindiville SA, Sarna LP, Schnoll RA, Herbst RS, Cinciripini PM, Leischow SJ, Dresler CM, Fiore MC, Warren GW. Research Priorities, Measures, and Recommendations for Assessment of Tobacco Use in Clinical Cancer Research. Clinical Cancer Research 2016, 22: 1907-1913. PMID: 26888828, PMCID: PMC4861174, DOI: 10.1158/1078-0432.ccr-16-0104.Peer-Reviewed Original ResearchMeSH KeywordsAdvisory CommitteesGuidelines as TopicHumansMedical OncologyResearchRisk AssessmentTobacco UseConceptsTobacco use assessmentCancer patientsTobacco useClinical trialsTobacco dependence treatmentSecondhand smoke exposureNIH Clinical CenterClinical treatment trialsAlternative tobacco productsTobacco Use QuestionnaireTobacco use statusEffect of cessationClinical cancer researchTiming of assessmentCancer researchCessation approachesProtocol therapyStudy entrySmoke exposureTask ForceCigarette smokingAdverse outcomesTreatment trialsClinical centersDependence treatment
2015
Electronic Nicotine Delivery Systems: A Policy Statement From the American Association for Cancer Research and the American Society of Clinical Oncology
Brandon TH, Goniewicz ML, Hanna NH, Hatsukami DK, Herbst RS, Hobin JA, Ostroff JS, Shields PG, Toll BA, Tyne CA, Viswanath K, Warren GW. Electronic Nicotine Delivery Systems: A Policy Statement From the American Association for Cancer Research and the American Society of Clinical Oncology. Journal Of Clinical Oncology 2015, 33: 952-963. PMID: 25572671, DOI: 10.1200/jco.2014.59.4465.Peer-Reviewed Original ResearchConceptsElectronic nicotine delivery systemsClinical OncologyTobacco useAmerican SocietyCancer researchHarm-reduction devicesNumber one preventable causeAmerican AssociationJoint writing groupCombustible tobacco productsClinical cancer researchNicotine delivery systemsCombustible tobacco useAdverse health effectsChildproof capsFormer smokersCigarette smokingPreventable causeTobacco cessationSmoking ratesUS FoodDrug AdministrationENDS useDefinitive dataElectronic cigarettes
2014
American Society of Clinical Oncology Perspective: Raising the Bar for Clinical Trials by Defining Clinically Meaningful Outcomes
Ellis LM, Bernstein DS, Voest EE, Berlin JD, Sargent D, Cortazar P, Garrett-Mayer E, Herbst RS, Lilenbaum RC, Sima C, Venook AP, Gonen M, Schilsky RL, Meropol NJ, Schnipper LE. American Society of Clinical Oncology Perspective: Raising the Bar for Clinical Trials by Defining Clinically Meaningful Outcomes. Journal Of Clinical Oncology 2014, 32: 1277-1280. PMID: 24638016, DOI: 10.1200/jco.2013.53.8009.Peer-Reviewed Original Research
2013
Addressing Tobacco Use in Patients With Cancer: A Survey of American Society of Clinical Oncology Members
Warren GW, Marshall JR, Cummings KM, Toll BA, Gritz ER, Hutson A, Dibaj S, Herbst R, Mulshine JL, Hanna N, Dresler CA. Addressing Tobacco Use in Patients With Cancer: A Survey of American Society of Clinical Oncology Members. JCO Oncology Practice 2013, 9: 258-262. PMID: 23943904, PMCID: PMC3770508, DOI: 10.1200/jop.2013.001025.Peer-Reviewed Original ResearchMeSH KeywordsData CollectionHumansMedical OncologyNeoplasmsPractice Patterns, Physicians'Smoking CessationSocieties, MedicalTobacco UseConceptsCessation supportTobacco usePractice patternsASCO membersInitial visitCessation interventionsTobacco assessmentTobacco cessation supportTobacco cessation interventionsAmerican SocietyClinical Oncology membersClinical cancer careMost respondentsMedication optionsTobacco cessationCancer outcomesCancer careClinical OncologyPatientsPatient resistanceCancerOnline surveyCessationInterventionAdequate trainingAssessing Tobacco Use by Cancer Patients and Facilitating Cessation: An American Association for Cancer Research Policy Statement
Toll BA, Brandon TH, Gritz ER, Warren GW, Herbst RS, Tobacco and Cancer W. Assessing Tobacco Use by Cancer Patients and Facilitating Cessation: An American Association for Cancer Research Policy Statement. Clinical Cancer Research 2013, 19: 1941-1948. PMID: 23570694, PMCID: PMC5992896, DOI: 10.1158/1078-0432.ccr-13-0666.Peer-Reviewed Original ResearchConceptsTobacco useTobacco cessationCessation interventionsEvidence-based cessation interventionsTreatment-related toxicitySecond primary tumorsTobacco cessation interventionsQuality cancer careQuality of lifeAmerican AssociationCessation assistancePoor outcomeCancer careCancer patientsPrimary tumorOncology settingCancer recurrencePatientsTreatment efficacyTreatment settingsEvidence-based proceduresCancer leadCancerCancer progressionClinical infrastructure
2006
Clinical Cancer Advances 2006: Major Research Advances in Cancer Treatment, Prevention, and Screening—A Report From the American Society of Clinical Oncology
Ozols RF, Herbst RS, Colson YL, Gralow J, Bonner J, Curran WJ, Eisenberg BL, Ganz PA, Kramer BS, Kris MG, Markman M, Mayer RJ, Raghavan D, Reaman GH, Sawaya R, Schilsky RL, Schuchter LM, Sweetenham JW, Vahdat LT, Winn RJ. Clinical Cancer Advances 2006: Major Research Advances in Cancer Treatment, Prevention, and Screening—A Report From the American Society of Clinical Oncology. Journal Of Clinical Oncology 2006, 25: 146-162. PMID: 17158528, DOI: 10.1200/jco.2006.09.7030.Peer-Reviewed Original ResearchConceptsHuman papillomavirusClinical OncologyHER-2 positive breast cancerCancer researchCancer treatmentScreening—A ReportHalf of menChronic myelogenous leukemiaAmerican SocietyClinical cancer researchCertain common cancersGroup of diseasesBasic science discoveriesASCO recommendationsUseful therapyCervical cancerPreventive vaccineCancer careCancer deathCancer patientsCommon cancerNeck cancerClinical trialsBreast cancerGlobal burden
2005
Clinical Cancer Advances 2005: Major Research Advances in Cancer Treatment, Prevention, and Screening—A Report From the American Society of Clinical Oncology
Herbst RS, Bajorin DF, Bleiberg H, Blum D, Hao D, Johnson BE, Ozols RF, Demetri GD, Ganz PA, Kris MG, Levin B, Markman M, Raghavan D, Reaman GH, Sawaya R, Schuchter LM, Sweetenham JW, Vahdat LT, Vokes EE, Winn RJ, Mayer RJ. Clinical Cancer Advances 2005: Major Research Advances in Cancer Treatment, Prevention, and Screening—A Report From the American Society of Clinical Oncology. Journal Of Clinical Oncology 2005, 24: 190-205. PMID: 16326753, DOI: 10.1200/jco.2005.04.8678.Peer-Reviewed Original ResearchConceptsClinical OncologyCancer typesClinical researchCancer treatmentScreening—A ReportRisk of recurrenceCancer therapyAmerican SocietyQuality of lifeSignificant clinical researchStudy of drugsCancer survivorsCommon cancerClinical trialsEffective therapyTargeted cancer therapyLong-term effectsNew chemotherapySurvival ratePatient careCancerTherapyEnormous tollDiseaseCancer research