2023
Telomeres cooperate with the nuclear envelope to maintain genome stability
Rai R, Sodeinde T, Boston A, Chang S. Telomeres cooperate with the nuclear envelope to maintain genome stability. BioEssays 2023, 46: e2300184. PMID: 38047499, DOI: 10.1002/bies.202300184.Peer-Reviewed Original ResearchNuclear envelopeGenome stabilityNuclear envelope ruptureKu70/Ku80Homology-directed recombinationMammalian telomeresChromosome stabilityNuclear laminsShelterin componentsProtein TRF2Envelope ruptureRepair proteinsTelomeresRap1Recent findingsProteinFunction resultsRecombinationDNA sensingForm structuresLaminsTRF2Ku80DNAHomeostasis
2008
Control of chromosome stability by the β-TrCP–REST–Mad2 axis
Guardavaccaro D, Frescas D, Dorrello NV, Peschiaroli A, Multani AS, Cardozo T, Lasorella A, Iavarone A, Chang S, Hernando E, Pagano M. Control of chromosome stability by the β-TrCP–REST–Mad2 axis. Nature 2008, 452: 365-369. PMID: 18354482, PMCID: PMC2707768, DOI: 10.1038/nature06641.Peer-Reviewed Original ResearchMeSH KeywordsBeta-Transducin Repeat-Containing ProteinsCalcium-Binding ProteinsCell Cycle ProteinsCell LineChromosomal InstabilityG2 PhaseGene Expression RegulationGenomic InstabilityHumansMad2 ProteinsMitosisProtein BindingRepressor ProteinsSKP Cullin F-Box Protein LigasesSpindle ApparatusTranscription Factors