Sinonasal Glomangiopericytoma: Review of Imaging Appearance and Clinical Management Update for a Rare Sinonasal Neoplasm.
Al-Jobory YM, Pan Z, Manes RP, Omay SB, Ikuta I. Sinonasal Glomangiopericytoma: Review of Imaging Appearance and Clinical Management Update for a Rare Sinonasal Neoplasm. The Yale Journal Of Biology And Medicine 2021, 94: 593-597. PMID: 34970096, PMCID: PMC8686777.Peer-Reviewed Original ResearchConceptsWorld Health OrganizationParanasal sinusesNasal cavityClinical management updateRare sinonasal neoplasmSlight female predominanceLow malignant potentialComplete surgical excisionNon-specific appearanceCase of glomangiopericytomaDecade of ageAggressive treatmentExcellent prognosisSinus massFemale predominanceLocal excisionLocal recurrenceMale patientsSurgical excisionRare tumorMalignant potentialImaging appearancesSinonasal neoplasmsSinonasal cavityTumor extentPIK3CA mutation in a case of CTNNB1 mutant sinonasal glomangiopericytoma
Hong C, Khan M, Sukys J, Prasad M, Erson-Omay EZ, Vining E, Omay SB. PIK3CA mutation in a case of CTNNB1 mutant sinonasal glomangiopericytoma. Molecular Case Studies 2021, 8: mcs.a006120. PMID: 34667073, PMCID: PMC8744496, DOI: 10.1101/mcs.a006120.Peer-Reviewed Original ResearchConceptsCase of glomangiopericytomaWhole-exome sequencingInstitutional review board-approved protocolTargeted medical therapyUnderwent surgical resectionPI3K/Akt/mTORWnt/β-cateninAkt/mTORPrimary sinonasal tumorSurgical resectionClinicopathologic characteristicsMedical therapyRare tumorPIK3CA mutationsSinonasal tumorsGlomangiopericytomaTumorsΒ-cateninSomatic mutationsComprehensive genetic characterizationGenomic characterizationMutationsConcurrent dysregulationResectionSinonasal