2013
Admission Insular Infarction >25% Is the Strongest Predictor of Large Mismatch Loss in Proximal Middle Cerebral Artery Stroke
Kamalian S, Kemmling A, Borgie RC, Morais LT, Payabvash S, Franceschi AM, Kamalian S, Yoo AJ, Furie KL, Lev MH. Admission Insular Infarction >25% Is the Strongest Predictor of Large Mismatch Loss in Proximal Middle Cerebral Artery Stroke. Stroke 2013, 44: 3084-3089. PMID: 23988643, PMCID: PMC3894265, DOI: 10.1161/strokeaha.113.002260.Peer-Reviewed Original ResearchConceptsInfarct volumeInsular infarctionHealth Stroke Scale scoreMiddle cerebral artery infarctConsecutive acute stroke patientsMiddle cerebral artery strokeProximal middle cerebral arteryRapid reperfusion therapyTreatment-eligible patientsAcute stroke patientsStroke Scale scoreFinal infarct volumeMiddle cerebral arteryStrongest predictorCharacteristic curve areaExcellent interobserver agreementDiffusion-weighted imaging imagesBinary logistic regressionArtery infarctInfarct progressionOcclusive strokePenumbral tissueReperfusion therapyCollateral scoreIndependent predictors
2012
Location-weighted CTP analysis predicts early motor improvement in stroke
Payabvash S, Souza LC, Kamalian S, Wang Y, Passanese J, Kamalian S, Fung SH, Halpern EF, Schaefer PW, Gonzalez RG, Furie KL, Lev MH. Location-weighted CTP analysis predicts early motor improvement in stroke. Neurology 2012, 78: 1853-1859. PMID: 22573641, PMCID: PMC3369521, DOI: 10.1212/wnl.0b013e318258f799.Peer-Reviewed Original ResearchConceptsAcute stroke patientsAdmission NIHSSMotor improvementStroke patientsCT perfusionPredictive valueOnly independent clinical predictorMultivariate binary logistic regressionFrontal lobe white matterMultivariate modelIndependent clinical predictorsMotor functional improvementMotor function improvementNegative predictive valuePositive predictive valueSuperior temporal gyrusBinary logistic regressionExtremity paresisAcute strokeSymptom onsetClinical predictorsConsecutive patientsIndependent predictorsClinical outcomesImaging predictors