Good Outcome Rate of 35% in IV-tPA–Treated Patients With Computed Tomography Angiography Confirmed Severe Anterior Circulation Occlusive Stroke
González RG, Furie KL, Goldmacher GV, Smith WS, Kamalian S, Payabvash S, Harris GJ, Halpern EF, Koroshetz WJ, Camargo EC, Dillon WP, Lev MH. Good Outcome Rate of 35% in IV-tPA–Treated Patients With Computed Tomography Angiography Confirmed Severe Anterior Circulation Occlusive Stroke. Stroke 2013, 44: 3109-3113. PMID: 24003051, PMCID: PMC4374554, DOI: 10.1161/strokeaha.113.001938.Peer-Reviewed Original ResearchConceptsAnterior circulation occlusionGood outcome rateIV-tPACT angiographyBetter outcomesRankin ScaleOutcome ratesAnterior circulation ischemic strokeHealth Stroke Scale scoreIntravenous tissue plasminogen activatorAdmission National InstitutesEndovascular therapy trialsNoncontrast CT scanningStroke Scale scoreLarge artery occlusionIV-tPA treatmentLogistic regression analysisTissue plasminogen activatorRoutine clinical protocolsSymptomatic strokeOcclusive strokeAcute strokeAdmission NIHSSArtery occlusionIschemic strokeAdmission Insular Infarction >25% Is the Strongest Predictor of Large Mismatch Loss in Proximal Middle Cerebral Artery Stroke
Kamalian S, Kemmling A, Borgie RC, Morais LT, Payabvash S, Franceschi AM, Kamalian S, Yoo AJ, Furie KL, Lev MH. Admission Insular Infarction >25% Is the Strongest Predictor of Large Mismatch Loss in Proximal Middle Cerebral Artery Stroke. Stroke 2013, 44: 3084-3089. PMID: 23988643, PMCID: PMC3894265, DOI: 10.1161/strokeaha.113.002260.Peer-Reviewed Original ResearchConceptsInfarct volumeInsular infarctionHealth Stroke Scale scoreMiddle cerebral artery infarctConsecutive acute stroke patientsMiddle cerebral artery strokeProximal middle cerebral arteryRapid reperfusion therapyTreatment-eligible patientsAcute stroke patientsStroke Scale scoreFinal infarct volumeMiddle cerebral arteryStrongest predictorCharacteristic curve areaExcellent interobserver agreementDiffusion-weighted imaging imagesBinary logistic regressionArtery infarctInfarct progressionOcclusive strokePenumbral tissueReperfusion therapyCollateral scoreIndependent predictors