2024
Automated detection of early signs of irreversible ischemic change on CTA source images in patients with large vessel occlusion
Mak A, Matouk C, Avery E, Behland J, Haider S, Frey D, Madai V, Vajkoczy P, Griessenauer C, Zand R, Hendrix P, Abedi V, Sanelli P, Falcone G, Petersen N, Sansing L, Sheth K, Payabvash S, Malhotra A. Automated detection of early signs of irreversible ischemic change on CTA source images in patients with large vessel occlusion. PLOS ONE 2024, 19: e0304962. PMID: 38870240, PMCID: PMC11175522, DOI: 10.1371/journal.pone.0304962.Peer-Reviewed Original ResearchConceptsDiffusion-weighted imagingLarge vessel occlusionIrreversible ischemic changesPoor functional outcomeFunctional outcomesIschemic changesInfarct volumeAlberta Stroke Program Early CT ScorePredicting poor functional outcomeVessel occlusionFollow-up diffusion-weighted imagingAnterior circulation LVO strokeCTA source imagesReceiver operating characteristic curveExpert human readersPredicting final infarctionASPECTS regionsAdmission CTANon-inferior performanceBaseline CTACT scoreFinal infarctEndovascular therapyHU attenuationValidation cohort
2021
Rapid Assessment of Blood Pressure Variability and Outcome After Successful Thrombectomy
Castro P, Ferreira F, Nguyen CK, Payabvash S, Tan C, Sorond F, Azevedo E, Petersen N. Rapid Assessment of Blood Pressure Variability and Outcome After Successful Thrombectomy. Stroke 2021, 52: e531-e535. PMID: 34311565, PMCID: PMC8384685, DOI: 10.1161/strokeaha.121.034291.Peer-Reviewed Original ResearchConceptsBlood pressure variabilityEndovascular stroke therapyBP variabilityFunctional outcomeNeurological recoveryStroke therapyPressure variabilityAnterior circulation ischemic strokeHigh blood pressure variabilityLong-term functional outcomeBP variability measuresEarly clinical improvementEarly neurological recoveryPersonalized BP managementFavorable functional outcomeInitial clinical responsePoor functional outcomeRisk assessment toolSuccessful reperfusionClinical improvementClinical responseIschemic strokeRankin ScaleSuccessful thrombectomyPostreperfusion period
2019
Poor Outcomes Related to Anterior Extension of Large Hemispheric Infarction: Topographic Analysis of GAMES-RP Trial MRI Scans
Payabvash S, Falcone GJ, Sze GK, Jain A, Beslow LA, Petersen NH, Sheth KN, Kimberly WT. Poor Outcomes Related to Anterior Extension of Large Hemispheric Infarction: Topographic Analysis of GAMES-RP Trial MRI Scans. Journal Of Stroke And Cerebrovascular Diseases 2019, 29: 104488. PMID: 31787498, PMCID: PMC8820410, DOI: 10.1016/j.jstrokecerebrovasdis.2019.104488.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, IntravenousAgedAnterior Cerebral ArteryCerebrovascular CirculationCerebrumClinical Trials as TopicClinical Trials, Phase II as TopicDiffusion Magnetic Resonance ImagingDisability EvaluationExtremitiesFemaleGlyburideHumansHypoglycemic AgentsInfarction, Anterior Cerebral ArteryInfarction, Middle Cerebral ArteryMaleMiddle AgedMiddle Cerebral ArteryPatient AdmissionPredictive Value of TestsRecovery of FunctionRisk FactorsTime FactorsTreatment OutcomeUnited StatesConceptsLarge hemispheric infarctionInfarct volumeIndependent predictorsInfarct lesionsHemispheric infarctionHealth Stroke Scale total scorePost-stroke day 3Anterior cerebral artery territoryTotal scoreLeft MCA infarctLeg motor functionNIHSS total scoreHours of onsetOnly independent predictorPoor functional outcomeBorder zoneScale total scoreAnterior extensionMultivariate regression analysisVoxel-wise analysisLHI patientsAdmission NIHSSArtery territoryGlibenclamide treatmentMCA infarct
2012
Malignant CTA Collateral Profile Is Highly Specific for Large Admission DWI Infarct Core and Poor Outcome in Acute Stroke
Souza LC, Yoo AJ, Chaudhry ZA, Payabvash S, Kemmling A, Schaefer PW, Hirsch JA, Furie KL, González RG, Nogueira RG, Lev MH. Malignant CTA Collateral Profile Is Highly Specific for Large Admission DWI Infarct Core and Poor Outcome in Acute Stroke. American Journal Of Neuroradiology 2012, 33: 1331-1336. PMID: 22383238, PMCID: PMC3888794, DOI: 10.3174/ajnr.a2985.Peer-Reviewed Original ResearchConceptsDWI lesion volumeLesion volumeDWI volumeNIHSS scorePoor outcomeHigher median NIHSS scoresROC analysisDWI lesion sizeLarger DWI volumeMedian NIHSS scoreAcute stroke treatmentAdmission NIHSS scoreOnly independent predictorPoor functional outcomeIntracranial ICA occlusionCTA collateralsAcute strokeICA occlusionProximal occlusionIndependent predictorsStroke treatmentInfarct sizeClinical variablesFunctional outcomeInfarct core