2022
Impact of collateral flow on cost-effectiveness of endovascular thrombectomy.
Khunte M, Wu X, Avery EW, Gandhi D, Payabvash S, Matouk C, Heit JJ, Wintermark M, Albers GW, Sanelli P, Malhotra A. Impact of collateral flow on cost-effectiveness of endovascular thrombectomy. Journal Of Neurosurgery 2022, 137: 1801-1810. PMID: 35535841, DOI: 10.3171/2022.2.jns212887.Peer-Reviewed Original ResearchConceptsIncremental cost-effectiveness ratioEndovascular thrombectomyIschemic stroke patientsCollateral statusPoor collateral statusBetter outcomesPoor collateralsCollateral circulationStroke patientsAcute ischemic stroke patientsModified Rankin Scale scorePoor collateral circulationRankin Scale scoreLarge vessel occlusionCollateral blood flowGood collateral blood flowCost-effectiveness ratioBase-case analysisProbabilistic sensitivity analysesEVT strategyEVT treatmentIschemic strokeMedical therapyMore patientsCollateral flow
2021
Similar admission NIHSS may represent larger tissue-at-risk in patients with right-sided versus left-sided large vessel occlusion
Mak A, Matouk C, Avery EW, Behland J, Frey D, Madai VI, Vajkoczy P, Malhotra A, Karam A, Sanelli P, Falcone GJ, Petersen NH, Sansing L, Sheth KN, Payabvash S. Similar admission NIHSS may represent larger tissue-at-risk in patients with right-sided versus left-sided large vessel occlusion. Journal Of NeuroInterventional Surgery 2021, 14: 985-991. PMID: 34645705, DOI: 10.1136/neurintsurg-2021-017785.Peer-Reviewed Original ResearchConceptsLarge vessel occlusionFinal infarct volumeLarger final infarct volumeWorse discharge outcomesInfarct volumeAdmission NIHSSDischarge outcomesVessel occlusionScale scoreMultivariate analysisAnterior large vessel occlusionLower admission NIHSS scoreHealth Stroke Scale scoreAdmission National InstitutesAdmission stroke severityPoor discharge outcomeStroke Scale scoreLarger infarct volumesAdmission NIHSS scoreRankin Scale scoreVoxel-wise analysisIncomplete reperfusionInfarct distributionOcclusion sideNIHSS scoreAdmission computed tomography radiomic signatures outperform hematoma volume in predicting baseline clinical severity and functional outcome in the ATACH‐2 trial intracerebral hemorrhage population
Haider SP, Qureshi AI, Jain A, Tharmaseelan H, Berson ER, Zeevi T, Majidi S, Filippi CG, Iseke S, Gross M, Acosta JN, Malhotra A, Kim JA, Sansing LH, Falcone GJ, Sheth KN, Payabvash S. Admission computed tomography radiomic signatures outperform hematoma volume in predicting baseline clinical severity and functional outcome in the ATACH‐2 trial intracerebral hemorrhage population. European Journal Of Neurology 2021, 28: 2989-3000. PMID: 34189814, PMCID: PMC8818333, DOI: 10.1111/ene.15000.Peer-Reviewed Original ResearchConceptsAdmission Glasgow Coma ScaleGlasgow Coma ScaleRadiomics signatureMRS scoreHematoma volumeICH volumeClinical severityNoncontrast head CT scansAdmission National InstitutesHealth Stroke ScaleRankin Scale scoreStrong associationBaseline clinical severityMedium-term outcomesIndependent validation cohortHead CT scanATACH-2 trialStroke ScaleAdmission NIHSSIndependent predictorsClinical presentationComa ScaleBaseline CTICH patientsValidation cohort
2020
Effects of Collateral Status on Infarct Distribution Following Endovascular Therapy in Large Vessel Occlusion Stroke
Al-Dasuqi K, Payabvash S, Torres-Flores GA, Strander SM, Nguyen CK, Peshwe KU, Kodali S, Silverman A, Malhotra A, Johnson MH, Matouk CC, Schindler JL, Sansing LH, Falcone GJ, Sheth KN, Petersen NH. Effects of Collateral Status on Infarct Distribution Following Endovascular Therapy in Large Vessel Occlusion Stroke. Stroke 2020, 51: e193-e202. PMID: 32781941, PMCID: PMC7484023, DOI: 10.1161/strokeaha.120.029892.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overArterial Occlusive DiseasesCerebral InfarctionCohort StudiesCollateral CirculationComputed Tomography AngiographyEndovascular ProceduresFemaleHumansInfarction, Middle Cerebral ArteryLinear ModelsMagnetic Resonance AngiographyMaleMiddle AgedReperfusionRetrospective StudiesStrokeThrombectomyTreatment OutcomeWhite MatterConceptsLarge vessel occlusion strokeFinal infarct volumeCollateral statusPoor collateral statusFavorable outcomeInfarct distributionInfarct volumeReperfusion successIndependent predictorsOcclusion strokeInternal capsuleAnterior circulation large vessel occlusion ischemic strokeLarge vessel occlusion ischemic strokeDeep white matter tractsBaseline collateral statusBorder-zone infarctionEarly favorable outcomeEarly functional outcomesRankin Scale scoreCohort of patientsDegree of reperfusionLarge vessel occlusionComputed tomography angiographyDeep white matterMagnetic resonance imaging
2019
Comparative Effectiveness of Endovascular Thrombectomy in Elderly Stroke Patients
Malhotra A, Wu X, Payabvash S, Matouk CC, Forman HP, Gandhi D, Sanelli P, Schindler J. Comparative Effectiveness of Endovascular Thrombectomy in Elderly Stroke Patients. Stroke 2019, 50: 963-969. PMID: 30908156, DOI: 10.1161/strokeaha.119.025031.Peer-Reviewed Original ResearchConceptsQuality-adjusted life yearsIntravenous thrombolysisEndovascular thrombectomyLarge vessel occlusionAge 80 yearsEVT strategyVessel occlusionModified Rankin Scale scorePoststroke functional outcomeAcute ischemic strokeRankin Scale scoreElderly stroke patientsMarkov decision-analytic modelYears of ageDecision analytic modelMultiple sensitivity analysesPurpose- StrokeAcute strokeBaseline disabilityElderly patientsIschemic strokeStroke patientsFunctional outcomeHealthy patientsAdvanced age
2017
Multivariate Prognostic Model of Acute Stroke Combining Admission Infarct Location and Symptom Severity: A Proof-of-Concept Study
Payabvash S, Benson JC, Tyan AE, Taleb S, McKinney AM. Multivariate Prognostic Model of Acute Stroke Combining Admission Infarct Location and Symptom Severity: A Proof-of-Concept Study. Journal Of Stroke And Cerebrovascular Diseases 2017, 27: 936-944. PMID: 29198948, DOI: 10.1016/j.jstrokecerebrovasdis.2017.10.034.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overArea Under CurveBrainBrain IschemiaBrain MappingDatabases, FactualDecision Support TechniquesDiffusion Magnetic Resonance ImagingDisability EvaluationFemaleHumansLogistic ModelsMaleMesencephalonMiddle AgedMultivariate AnalysisOdds RatioPatient AdmissionPonsPredictive Value of TestsProof of Concept StudyReproducibility of ResultsRetrospective StudiesRisk FactorsROC CurveSeverity of Illness IndexStrokeTime FactorsTreatment OutcomeConceptsDisability/deathMidbrain/ponsAcute ischemic stroke patientsIschemic stroke patientsAdmission NIHSS scoreStroke patientsNIHSS scoreIndependent predictorsInfarct locationScale scoreHealth Stroke Scale scoreHigher admission NIHSS scoresModified Rankin Scale scoreSymptom severityAdmission stroke severityBaseline functional disabilityLarger infarct volumesStroke Scale scoreRankin Scale scoreHours of onsetAcute ischemic infarctMultivariate prognostic modelMajor arterial occlusionHypothesis-generating studyVoxel-based analysisCerebral regions preserved by successful endovascular recanalization of acute M1 segment occlusions: a voxel based analysis
Payabvash S, Taleb S, Qureshi AI. Cerebral regions preserved by successful endovascular recanalization of acute M1 segment occlusions: a voxel based analysis. British Journal Of Radiology 2017, 90: 20160869. PMID: 28165757, PMCID: PMC5605076, DOI: 10.1259/bjr.20160869.Peer-Reviewed Original ResearchConceptsM1 segment occlusionDisability/deathSuccessful endovascular recanalizationVoxel-based analysisFinal infarct volumeSuccessful recanalizationSegment occlusionInfarct volumeFavorable outcomePrecentral gyrusCerebral regionsEndovascular recanalizationEndovascular treatmentInsular ribbonSmaller final infarct volumesDays post-symptom onsetMiddle cerebral artery M1 segmentModified Rankin Scale scoreCerebral Infarction scoreTimely reperfusion treatmentEarly clinical outcomesHigh ratePost-symptom onsetSmaller infarct volumesRankin Scale score
2016
Topographic Assessment of Acute Ischemic Changes for Prognostication of Anterior Circulation Stroke
Payabvash S, Noorbaloochi S, Qureshi AI. Topographic Assessment of Acute Ischemic Changes for Prognostication of Anterior Circulation Stroke. Journal Of Neuroimaging 2016, 27: 227-231. PMID: 27593522, DOI: 10.1111/jon.12383.Peer-Reviewed Original ResearchConceptsAlberta Stroke Program Early CT ScoreDisability/deathAnterior circulation strokeAcute ischemic changesSymptomatic intracranial hemorrhageIntracranial hemorrhageIschemic changesIndependent predictorsFavorable outcomeIntravenous thrombolytic therapyCT/MRI scansRankin Scale scoreEarly ischemic changesAcute ischemic infarctTopographic assessmentIschemic infarctAdmission CTClinical outcomesStroke patientsThrombolytic therapyCT scoreLentiform nucleusTomography scanImproved outcomesPrognostic toolClinical implications of eye deviation on admission CT examination of acute ischaemic stroke patients
Payabvash S, Qureshi I, Qureshi AI. Clinical implications of eye deviation on admission CT examination of acute ischaemic stroke patients. Clinical Radiology 2016, 71: 1314.e11-1314.e15. PMID: 27592397, DOI: 10.1016/j.crad.2016.08.002.Peer-Reviewed Original ResearchConceptsAlberta Stroke Program Early CT ScoreAcute ischemic stroke patientsIschemic stroke patientsHigher admission NIHSS scoresAdmission NIHSS scoreEye deviationStroke patientsNIHSS scoreHaemorrhagic transformationCT examinationsLow Alberta Stroke Program Early CT ScoreScale scoreHealth Stroke Scale scoreOlder ageAdmission CT examinationAdmission National InstitutesPatients' older ageStroke Scale scoreHigh rateRankin Scale scoreInfarct volumeMRS scoreAdmission CTCT scorePrognostic valueInterhemispheric Asymmetry in Distribution of Infarct Lesions among Acute Ischemic Stroke Patients Presenting to Hospital
Payabvash S, Taleb S, Benson JC, McKinney AM. Interhemispheric Asymmetry in Distribution of Infarct Lesions among Acute Ischemic Stroke Patients Presenting to Hospital. Journal Of Stroke And Cerebrovascular Diseases 2016, 25: 2464-2469. PMID: 27373730, DOI: 10.1016/j.jstrokecerebrovasdis.2016.06.019.Peer-Reviewed Original ResearchConceptsRight-sided strokeLeft-sided strokeAcute ischemic stroke patientsEarly clinical outcomesIschemic stroke patientsIschemic infarctInfarct lesionsInsular ribbonVoxel-based analysisClinical outcomesStroke patientsLentiform nucleusScale scoreHealth Stroke Scale scoreModified Rankin Scale scoreSymptom severityStroke risk factorsStroke Scale scoreHours of onsetRankin Scale scoreAcute ischemic infarctRate of treatmentAdmission symptomsSymptomatic infarctsRisk factors
2012
Improved Outcome Prediction Using CT Angiography in Addition to Standard Ischemic Stroke Assessment: Results from the STOPStroke Study
González RG, Lev MH, Goldmacher GV, Smith WS, Payabvash S, Harris GJ, Halpern EF, Koroshetz WJ, Camargo EC, Dillon WP, Furie KL. Improved Outcome Prediction Using CT Angiography in Addition to Standard Ischemic Stroke Assessment: Results from the STOPStroke Study. PLOS ONE 2012, 7: e30352. PMID: 22276182, PMCID: PMC3262833, DOI: 10.1371/journal.pone.0030352.Peer-Reviewed Original ResearchConceptsPoor outcomeCT angiographyStroke assessmentOdds ratioNoncontrast CTAdmission NIH Stroke Scale scoreAlberta Stroke Program Early CT ScoreBoston Acute Stroke Imaging ScaleScale scoreModified Rankin Scale scoreNIH Stroke Scale scoreOutcome predictionAcute stroke assessmentAdmission CT angiographyProximal middle cerebralStroke Scale scoreAcute ischemic strokeRankin Scale scoreDistal internal carotidIndependent outcome predictorsStroke outcome predictionSignificant clinical toolNCCT ASPECTSIschemic strokeMiddle cerebral