2019
Poor Outcomes Related to Anterior Extension of Large Hemispheric Infarction: Topographic Analysis of GAMES-RP Trial MRI Scans
Payabvash S, Falcone GJ, Sze GK, Jain A, Beslow LA, Petersen NH, Sheth KN, Kimberly WT. Poor Outcomes Related to Anterior Extension of Large Hemispheric Infarction: Topographic Analysis of GAMES-RP Trial MRI Scans. Journal Of Stroke And Cerebrovascular Diseases 2019, 29: 104488. PMID: 31787498, PMCID: PMC8820410, DOI: 10.1016/j.jstrokecerebrovasdis.2019.104488.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, IntravenousAgedAnterior Cerebral ArteryCerebrovascular CirculationCerebrumClinical Trials as TopicClinical Trials, Phase II as TopicDiffusion Magnetic Resonance ImagingDisability EvaluationExtremitiesFemaleGlyburideHumansHypoglycemic AgentsInfarction, Anterior Cerebral ArteryInfarction, Middle Cerebral ArteryMaleMiddle AgedMiddle Cerebral ArteryPatient AdmissionPredictive Value of TestsRecovery of FunctionRisk FactorsTime FactorsTreatment OutcomeUnited StatesConceptsLarge hemispheric infarctionInfarct volumeIndependent predictorsInfarct lesionsHemispheric infarctionHealth Stroke Scale total scorePost-stroke day 3Anterior cerebral artery territoryTotal scoreLeft MCA infarctLeg motor functionNIHSS total scoreHours of onsetOnly independent predictorPoor functional outcomeBorder zoneScale total scoreAnterior extensionMultivariate regression analysisVoxel-wise analysisLHI patientsAdmission NIHSSArtery territoryGlibenclamide treatmentMCA infarct
2016
Prominent cortical and medullary veins on susceptibility-weighted images of acute ischaemic stroke
Payabvash S, Benson JC, Taleb S, Rykken JB, Hoffman B, Oswood MC, McKinney AM. Prominent cortical and medullary veins on susceptibility-weighted images of acute ischaemic stroke. British Journal Of Radiology 2016, 89: 20160714. PMID: 27805839, PMCID: PMC5604931, DOI: 10.1259/bjr.20160714.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrain IschemiaCerebral ArteriesCerebrovascular CirculationFemaleHumansMagnetic Resonance AngiographyMagnetic Resonance ImagingMaleMiddle AgedProspective StudiesStrokeConceptsAcute ischemic strokeLarger infarct volumesMedullary veinsIschemic strokeInfarct volumeArterial occlusionSusceptibility-weighted imagesConsecutive patientsClinical outcomesCortical veinsProminent cortical veinsPosterior circulation territoryPoor clinical outcomeSeverity of symptomsFair interobserver agreementSWI seriesAcute strokeSymptom onsetIndependent predictorsClinical variablesSWI scansPatientsStrokeImaging implicationsProminent veinsTopographic Assessment of Acute Ischemic Changes for Prognostication of Anterior Circulation Stroke
Payabvash S, Noorbaloochi S, Qureshi AI. Topographic Assessment of Acute Ischemic Changes for Prognostication of Anterior Circulation Stroke. Journal Of Neuroimaging 2016, 27: 227-231. PMID: 27593522, DOI: 10.1111/jon.12383.Peer-Reviewed Original ResearchConceptsAlberta Stroke Program Early CT ScoreDisability/deathAnterior circulation strokeAcute ischemic changesSymptomatic intracranial hemorrhageIntracranial hemorrhageIschemic changesIndependent predictorsFavorable outcomeIntravenous thrombolytic therapyCT/MRI scansRankin Scale scoreEarly ischemic changesAcute ischemic infarctTopographic assessmentIschemic infarctAdmission CTClinical outcomesStroke patientsThrombolytic therapyCT scoreLentiform nucleusTomography scanImproved outcomesPrognostic toolClinical diffusion mismatch better discriminates infarct growth than mean transit time–diffusion weighted imaging mismatch in patients with middle cerebral artery–M1 occlusion and limited infarct core
Nogueira RG, Kemmling A, Souza LM, Payabvash S, Hirsch JA, Yoo AJ, Lev MH. Clinical diffusion mismatch better discriminates infarct growth than mean transit time–diffusion weighted imaging mismatch in patients with middle cerebral artery–M1 occlusion and limited infarct core. Journal Of NeuroInterventional Surgery 2016, 9: 127. PMID: 26957483, DOI: 10.1136/neurintsurg-2014-011602.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCerebral AngiographyCerebral InfarctionCerebrovascular CirculationDiffusion Magnetic Resonance ImagingDisease ProgressionFemaleHumansImage Processing, Computer-AssistedInfarction, Middle Cerebral ArteryMalePredictive Value of TestsRetrospective StudiesStrokeTomography, X-Ray ComputedConceptsClinical-diffusion mismatchMCA M1 occlusionAdmission Alberta Stroke Program Early CT scoreSmall infarct coreBaseline NIHSS scoreInfarct growthNIHSS scoreInfarct coreDiffusion mismatchDWI volumeStroke patientsAlberta Stroke Program Early CT ScoreMiddle cerebral artery M1 occlusionProximal middle cerebral artery occlusionMiddle cerebral artery occlusionMTT lesionsUni-/multivariate analysesBaseline National InstitutesHealth Stroke ScaleAdmission NIHSS scoreCerebral artery occlusionConsecutive stroke patientsOnly independent predictorDWI lesionsStroke Scale
2015
Acute CT perfusion changes in seizure patients presenting to the emergency department with stroke-like symptoms: correlation with clinical and electroencephalography findings
Payabvash S, Oswood MC, Truwit CL, McKinney AM. Acute CT perfusion changes in seizure patients presenting to the emergency department with stroke-like symptoms: correlation with clinical and electroencephalography findings. Clinical Radiology 2015, 70: 1136-1143. PMID: 26155937, DOI: 10.1016/j.crad.2015.06.078.Peer-Reviewed Original ResearchMeSH KeywordsAgedBrainCerebrovascular CirculationElectroencephalographyEmergency Service, HospitalFemaleHumansMaleMiddle AgedRetrospective StudiesSeizuresTomography, X-Ray ComputedConceptsRelative cerebral blood flowRelative mean transit timeStroke-like symptomsSeizure patientsPerfusion changesClinical presentationEmergency departmentCTP examinationAcute stroke-like presentationAcute stroke-like symptomsNon-focal neurological deficitsSpeech deficitsStroke-like presentationSubset of patientsDifferent clinical presentationsCerebral blood flowEloquent brain regionsAdmission CTPElectroencephalography findingsNeurological deficitsSymptom onsetSuch patientsEarly followEEG findingsUnilateral motorComparison of CT perfusion summary maps to early diffusion-weighted images in suspected acute middle cerebral artery stroke
Benson J, Payabvash S, Salazar P, Jagadeesan B, Palmer CS, Truwit CL, McKinney AM. Comparison of CT perfusion summary maps to early diffusion-weighted images in suspected acute middle cerebral artery stroke. European Journal Of Radiology 2015, 84: 682-689. PMID: 25623829, DOI: 10.1016/j.ejrad.2014.12.026.Peer-Reviewed Original ResearchConceptsAlberta Stroke Program Early CT ScoreASPECTS scoreAcute middle cerebral artery strokeMiddle cerebral artery strokeAge-matched patientsDWI infarct volumeDiffusion-weighted imagingInfarct volumePositive patientsSymptom onsetArtery strokeCT scoreDiffusion-weighted imagesInfarct coreCTP examinationDWI volumePatientsDWIInfarctsScores
2011
Admission CT Perfusion Is an Independent Predictor of Hemorrhagic Transformation in Acute Stroke with Similar Accuracy to DWI
Souza LC, Payabvash S, Wang Y, Kamalian S, Schaefer P, Gonzalez RG, Furie KL, Lev MH. Admission CT Perfusion Is an Independent Predictor of Hemorrhagic Transformation in Acute Stroke with Similar Accuracy to DWI. Cerebrovascular Diseases 2011, 33: 8-15. PMID: 22143195, PMCID: PMC3250646, DOI: 10.1159/000331914.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBostonCerebrovascular CirculationChi-Square DistributionDiffusion Magnetic Resonance ImagingFemaleHumansIntracranial HemorrhagesLogistic ModelsMaleMiddle AgedMultivariate AnalysisPatient AdmissionPerfusion ImagingPredictive Value of TestsPrognosisRetrospective StudiesRisk AssessmentRisk FactorsROC CurveStrokeTomography, X-Ray ComputedConceptsRelative mean transit timeAdmission CT perfusionDiffusion-weighted imagingPredictors of HTRelative cerebral blood flowHemorrhagic transformationCT perfusionAcute strokeIndependent predictorsTissue volumeAdmission diffusion-weighted imagingConsecutive stroke patientsOnly independent predictorCerebral blood flowIschemic hemisphereMechanical thrombectomyStroke patientsInfarct coreMean transit timeBlood flowTest characteristicsCurve analysisDWI scansLesionsStrokeCT Cerebral Blood Flow Maps Optimally Correlate With Admission Diffusion-Weighted Imaging in Acute Stroke but Thresholds Vary by Postprocessing Platform
Kamalian S, Kamalian S, Maas MB, Goldmacher GV, Payabvash S, Akbar A, Schaefer PW, Furie KL, Gonzalez RG, Lev MH. CT Cerebral Blood Flow Maps Optimally Correlate With Admission Diffusion-Weighted Imaging in Acute Stroke but Thresholds Vary by Postprocessing Platform. Stroke 2011, 42: 1923-1928. PMID: 21546490, PMCID: PMC3125441, DOI: 10.1161/strokeaha.110.610618.Peer-Reviewed Original ResearchConceptsDiffusion-weighted imagingCT perfusion parametersAcute strokeCT perfusionInfarct coreAdmission diffusion-weighted imagingPerfusion parametersCerebral blood flowCerebral blood flow mapsCerebral blood volumeCharacteristic curve analysisAdmission CT perfusionBlood flow mapsUninvolved hemisphereRegional Ischemic Vulnerability of the Brain to Hypoperfusion
Payabvash S, Souza LC, Wang Y, Schaefer PW, Furie KL, Halpern EF, Gonzalez RG, Lev MH. Regional Ischemic Vulnerability of the Brain to Hypoperfusion. Stroke 2011, 42: 1255-1260. PMID: 21493917, PMCID: PMC3090217, DOI: 10.1161/strokeaha.110.600940.Peer-Reviewed Original ResearchMeSH KeywordsBrain IschemiaCaudate NucleusCerebral CortexCerebrovascular CirculationCohort StudiesFemaleHumansMalePerfusionPutamenRetrospective StudiesRisk FactorsStrokeTomography, X-Ray ComputedConceptsIschemic vulnerabilityStroke patientsInfarct coreRCBF thresholdAdmission diffusion-weighted imagingCerebral blood flow reductionAcute stroke patientsIschemic stroke onsetBlood flow reductionAdmission CT perfusionDiffusion-weighted imagingCT perfusion mapsStroke onsetRCBF reductionCT perfusionBrain lesionsInferior frontal gyrusParacentral lobuleCaudate bodyInsular ribbonPerfusion parameter mapsHypoperfusionSubcortical regionsPatientsRCBF