2020
Choice of imaging modality for pre-treatment staging of head and neck cancer impacts TNM staging
Mur T, Sambhu KM, Mahajan A, Payabvash S, Fernandez J, Edwards HA. Choice of imaging modality for pre-treatment staging of head and neck cancer impacts TNM staging. American Journal Of Otolaryngology 2020, 41: 102662. PMID: 32858370, DOI: 10.1016/j.amjoto.2020.102662.Peer-Reviewed Original ResearchConceptsPET/CTLow-dose nonenhanced CTDistant metastasisChest CTNeck cancerNonenhanced CTF-fluorodeoxyglucose positron emission tomographyF-FDG PET/CTDiagnostic chest CTDistant metastatic diseaseInitiation of therapyRetrospective cohort studyPre-treatment stagingTertiary care settingSignificant differencesPositron emission tomographyMetastatic diseaseCohort studyOncologic treatmentTNM stagingInaccurate stagingNeck radiologistsCare settingsSingle patientPatientsPET/CT radiomics signature of human papilloma virus association in oropharyngeal squamous cell carcinoma
Haider SP, Mahajan A, Zeevi T, Baumeister P, Reichel C, Sharaf K, Forghani R, Kucukkaya AS, Kann BH, Judson BL, Prasad ML, Burtness B, Payabvash S. PET/CT radiomics signature of human papilloma virus association in oropharyngeal squamous cell carcinoma. European Journal Of Nuclear Medicine And Molecular Imaging 2020, 47: 2978-2991. PMID: 32399621, DOI: 10.1007/s00259-020-04839-2.Peer-Reviewed Original ResearchConceptsOropharyngeal squamous cell carcinomaMetastatic cervical lymph nodesCervical lymph nodesLymph nodesSquamous cell carcinomaPrimary tumorPET/CTHPV associationCell carcinomaRadiomics signatureVolume of interestHuman papilloma virus associationHuman papillomavirus associationMulti-national cohortNon-contrast CTHPV statusFDG-PETExternal cohortVirus associationFinal modelTumorsRadiomic featuresCTSignificant differencesLesion featuresReply to A.B. Simon et al.
Kann BH, Payabvash S, Aneja S. Reply to A.B. Simon et al. Journal Of Clinical Oncology 2020, 38: 1869-1870. PMID: 32271673, DOI: 10.1200/jco.20.00402.Peer-Reviewed Original ResearchDeep LearningExtranodal ExtensionHead and Neck NeoplasmsHumansSquamous Cell Carcinoma of Head and Neck
2019
Multi-Institutional Validation of Deep Learning for Pretreatment Identification of Extranodal Extension in Head and Neck Squamous Cell Carcinoma.
Kann BH, Hicks DF, Payabvash S, Mahajan A, Du J, Gupta V, Park HS, Yu JB, Yarbrough WG, Burtness BA, Husain ZA, Aneja S. Multi-Institutional Validation of Deep Learning for Pretreatment Identification of Extranodal Extension in Head and Neck Squamous Cell Carcinoma. Journal Of Clinical Oncology 2019, 38: 1304-1311. PMID: 31815574, DOI: 10.1200/jco.19.02031.Peer-Reviewed Original ResearchConceptsNeck squamous cell carcinomaExtranodal extensionSquamous cell carcinomaLymph nodesCell carcinomaContrast-enhanced CT scanDiagnostic abilityBoard-certified neuroradiologistsTreatment escalationCancer Genome AtlasPathologic confirmationPretreatment identificationDiagnostic challengeExternal validation data setsPathology resultsPretreatment imagingPoor prognosticatorClinical utilityCT scanPatientsClinical decisionHNSCCDiagnostic accuracyInstitutional ValidationGenome AtlasDifferentiation of lymphomatous, metastatic, and non-malignant lymphadenopathy in the neck with quantitative diffusion-weighted imaging: systematic review and meta-analysis
Payabvash S, Brackett A, Forghani R, Malhotra A. Differentiation of lymphomatous, metastatic, and non-malignant lymphadenopathy in the neck with quantitative diffusion-weighted imaging: systematic review and meta-analysis. Neuroradiology 2019, 61: 897-910. PMID: 31175398, DOI: 10.1007/s00234-019-02236-7.Peer-Reviewed Original ResearchMeSH KeywordsDiagnosis, DifferentialDiffusion Magnetic Resonance ImagingHead and Neck NeoplasmsHumansLymphadenopathyLymphatic MetastasisConceptsCervical lymph nodesAverage apparent diffusion coefficientStandardized mean differenceLymph nodesNon-malignant nodesDiagnostic odds ratioCervical lymphadenopathySubgroup analysisADC thresholdSystematic reviewSuspicious cervical lymph nodesUnknown primary cancer siteMean differenceNon-malignant lymphadenopathyCochrane Central RegisterNeck lymph nodesPrimary cancer siteConfidence intervalsSROC AUCRandom-effects modelComprehensive literature searchAverage ADC valueDiffusion-weighted imagingQuantitative diffusion-weighted imagingCentral RegisterQuantitative diffusion magnetic resonance imaging for prediction of human papillomavirus status in head and neck squamous-cell carcinoma: A systematic review and meta-analysis
Payabvash S, Chan A, Maralani P, Malhotra A. Quantitative diffusion magnetic resonance imaging for prediction of human papillomavirus status in head and neck squamous-cell carcinoma: A systematic review and meta-analysis. The Neuroradiology Journal 2019, 32: 232-240. PMID: 31084347, PMCID: PMC6639646, DOI: 10.1177/1971400919849808.Peer-Reviewed Original ResearchConceptsNeck squamous cell carcinomaDiffusion-weighted imagingHPV-positive HNSCCSquamous cell carcinomaHPV-negative HNSCCPrimary tumor lesionsStandardized mean differenceQuantitative diffusion magnetic resonancePrimary lesionHPV statusTumor lesionsAverage ADCDiffusion magnetic resonanceMean differenceHiggins' inconsistency indexHuman papillomavirus (HPV) statusHuman papillomavirus infectionApparent diffusion coefficient (ADC) valuesRandom-effects modelNoninvasive imaging biomarkerComprehensive literature searchAverage ADC valueEcho-planar diffusion-weighted imagingFixed-effects modelPapillomavirus infection
2015
Differentiation of benign from malignant cervical lymph nodes in patients with head and neck cancer using PET/CT imaging
Payabvash S, Meric K, Cayci Z. Differentiation of benign from malignant cervical lymph nodes in patients with head and neck cancer using PET/CT imaging. Clinical Imaging 2015, 40: 101-105. PMID: 26454617, DOI: 10.1016/j.clinimag.2015.09.001.Peer-Reviewed Original ResearchMeSH KeywordsDiagnosis, DifferentialFemaleFluorodeoxyglucose F18Head and Neck NeoplasmsHumansImage-Guided BiopsyLymph NodesLymphatic DiseasesLymphatic MetastasisMaleMiddle AgedMultimodal ImagingNeckPositron-Emission TomographyRadiopharmaceuticalsRetrospective StudiesSensitivity and SpecificityTomography, X-Ray ComputedConceptsHead/neck cancerCervical lymph nodesMalignant cervical lymph nodesLymph nodesNeck cancerPositron emission tomographySUV maxHigh maximum standardized uptake valueBenign cervical lymph nodesMaximum standardized uptake valueLymph node biopsyMalignant lymph nodesMalignant cervical lymphadenopathyPET/CT imagingStandardized uptake valueSUV max valuesShort-axis diameterCervical lymphadenopathyNode biopsyMalignant lymphadenopathyRetrospective studyPatientsUptake valueEmission tomographyCancer