Evaluating the Accuracy and Utility of Large Language Models in Answering Common Contraception Questions [ID 2683633]
Patel A, Jasani S, AlAshqar A, Panakam A, Amin K, Sheth S. Evaluating the Accuracy and Utility of Large Language Models in Answering Common Contraception Questions [ID 2683633]. Obstetrics And Gynecology 2024, 143: 12s-12s. DOI: 10.1097/01.aog.0001013000.12240.72.Peer-Reviewed Original ResearchLanguage modelContraception questionsAmerican Academy of Family PhysiciansReproductive health educationBardLanguageMicrosoft BingKruskal-Wallis testTextReference textNo significant differenceEvidence basisAcademy of Family PhysiciansContraceptive counselingContraceptionKruskal-WallisAmerican AcademySignificant differenceAssess responsePhysician reviewReferralFamily physiciansQuestionsRandomized Phase II Trial of Imiquimod with or without 9-Valent HPV Vaccine versus Observation in Patients with High-grade Pre-neoplastic Cervical Lesions (NCT02864147)
Sheth S, Oh J, Bellone S, Siegel E, Greenman M, Mutlu L, McNamara B, Pathy S, Clark M, Azodi M, Altwerger G, Andikyan V, Huang G, Ratner E, Kim D, Iwasaki A, Levi A, Buza N, Hui P, Flaherty S, Schwartz P, Santin A. Randomized Phase II Trial of Imiquimod with or without 9-Valent HPV Vaccine versus Observation in Patients with High-grade Pre-neoplastic Cervical Lesions (NCT02864147). Clinical Cancer Research 2024, 30: of1-of10. PMID: 38592381, DOI: 10.1158/1078-0432.ccr-23-3639.Peer-Reviewed Original ResearchConceptsRandomized phase II trialCD4/CD8 T cellsT cellsHPV clearanceArm BNo significant differenceClinical surveillanceRate of HPV clearanceSecondary outcomesPre-neoplastic cervical lesionsCervical intraepithelial neoplasiaT cell infiltrationT cell responsesSignificant differenceCIN3 patientsIntraepithelial neoplasiaArm ACervical lesionsImiquimod groupSurveillance armVaginal suppositoriesProspective trialsArm CHPV vaccinationImiquimod