2023
Real-World Treatment Patterns and Overall Survival Among Newly Diagnosed and Relapsed/Refractory Acute Myeloid Leukemia (AML) Patients: A Retrospective Cohort Study Using Claims Data
Huntington S, Chang H, Fu A, Loefgren C, Lu X. Real-World Treatment Patterns and Overall Survival Among Newly Diagnosed and Relapsed/Refractory Acute Myeloid Leukemia (AML) Patients: A Retrospective Cohort Study Using Claims Data. Blood 2023, 142: 2428. DOI: 10.1182/blood-2023-178755.Peer-Reviewed Original ResearchHematopoietic stem cell transplantAcute myeloid leukemiaNon-transplant recipientsR AML patientsIndex dateAML patientsOverall survivalTreatment patternsND patientsIntensive chemotherapyAML diagnosisR patientsDiagnosis codesTransplant recipientsOlder patientsSupportive careIntensive therapyContinuous enrollmentNovel therapiesLarge US administrative claims databaseUnmet needRefractory acute myeloid leukemia patientsReal-world treatment patternsUS administrative claims databaseAcute myeloid leukemia patients
2020
Clinical outcomes of older patients with AML receiving hypomethylating agents: a large population-based study in the United States
Zeidan AM, Wang R, Wang X, Shallis RM, Podoltsev NA, Bewersdorf JP, Huntington SF, Neparidze N, Giri S, Gore SD, Davidoff AJ, Ma X. Clinical outcomes of older patients with AML receiving hypomethylating agents: a large population-based study in the United States. Blood Advances 2020, 4: 2192-2201. PMID: 32433746, PMCID: PMC7252544, DOI: 10.1182/bloodadvances.2020001779.Peer-Reviewed Original ResearchConceptsAcute myeloid leukemiaDecitabine-treated patientsTransfusion independenceRed blood cell transfusion independenceLarge population-based studyOlder AML patientsRBC transfusion independenceEnd Results-MedicarePopulation-based studyStandard of careAgent azacitidineMedian survivalOlder patientsIntensive therapyAML patientsClinical outcomesClinical benefitMyeloid leukemiaMortality riskPatientsAzacitidineDecitabineOlder adultsOne-thirdMeaningful differences