2022
Treatment Patterns of Follicular Lymphoma in the United States: A Claims Analysis
Huntington S, Appukkuttan S, Wang W, Du Y, Hopson S, Babajanyan S. Treatment Patterns of Follicular Lymphoma in the United States: A Claims Analysis. Journal Of Health Economics And Outcomes Research 2022, 9: 115-122. PMID: 36348725, PMCID: PMC9603402, DOI: 10.36469/001c.38070.Peer-Reviewed Original ResearchLines of therapyFirst-line treatmentFollicular lymphomaTreatment patternsRituximab monotherapyCommon first-line treatmentReal-world treatment patternsFourth-line therapyOptimal treatment sequencingThird-line therapyDuration of therapyInitiation of treatmentCommon indolent lymphomaLine of treatmentNumber of patientsActive regimensRituximab therapyBaseline characteristicsMost patientsRetrospective cohortIBM MarketScanPrimary outcomeContemporary cohortIndolent lymphomaMedian timeTreatment Patterns of Follicular Lymphoma in the United States: A Claims Analysis
Huntington S, Appukkuttan S, Wang W, Du Y, Hopson S, Babajanyan S. Treatment Patterns of Follicular Lymphoma in the United States: A Claims Analysis. Journal Of Health Economics And Outcomes Research 2022, 115-122. DOI: 10.36469/jheor.2022.38070.Peer-Reviewed Original ResearchLines of therapyFirst-line treatmentFollicular lymphomaTreatment patternsRituximab monotherapyCommon first-line treatmentReal-world treatment patternsFourth-line therapyOptimal treatment sequencingThird-line therapyDuration of therapyInitiation of treatmentCommon indolent lymphomaLine of treatmentNumber of patientsActive regimensRituximab therapyBaseline characteristicsMost patientsRetrospective cohortIBM MarketScanPrimary outcomeContemporary cohortIndolent lymphomaMedian time
2019
Chromosome 1 abnormalities and clinical outcomes in multiple myeloma in the era of novel agents.
Giri S, Huntington S, Wang R, Zeidan A, Podoltsev N, Gore S, Ma X, Gross C, Davidoff A, Neparidze N. Chromosome 1 abnormalities and clinical outcomes in multiple myeloma in the era of novel agents. Journal Of Clinical Oncology 2019, 37: 8044-8044. DOI: 10.1200/jco.2019.37.15_suppl.8044.Peer-Reviewed Original ResearchOverall survivalMultiple myelomaPerformance statusMultivariable Cox survival analysisMedian overall survivalPoor performance statusLines of therapyKaplan-Meier methodCox regression analysisDays of diagnosisWorse overall survivalCox survival analysisLog-rank testReal-world treatmentCommon genetic mutationsHigh-risk mutationsSitu hybridization testingElectronic health recordsISS stageReal-world practiceMedian ageMeier methodOS independentPrimary outcomeSpecific regimens
2017
R‐CHOP versus dose‐adjusted R‐EPOCH in frontline management of primary mediastinal B‐cell lymphoma: a multi‐centre analysis
Shah NN, Szabo A, Huntington SF, Epperla N, Reddy N, Ganguly S, Vose J, Obiozor C, Faruqi F, Kovach AE, Costa LJ, Xavier AC, Okal R, Kanate AS, Ghosh N, Kharfan‐Dabaja M, Strelec L, Hamadani M, Fenske TS, Calzada O, Cohen JB, Chavez J, Svoboda J. R‐CHOP versus dose‐adjusted R‐EPOCH in frontline management of primary mediastinal B‐cell lymphoma: a multi‐centre analysis. British Journal Of Haematology 2017, 180: 534-544. PMID: 29265182, DOI: 10.1111/bjh.15051.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAntibodies, Monoclonal, Murine-DerivedAntineoplastic Combined Chemotherapy ProtocolsCombined Modality TherapyCyclophosphamideDisease ManagementDoxorubicinEtoposideFemaleHumansLymphoma, B-CellMaleMediastinal NeoplasmsMiddle AgedNeoplasm GradingNeoplasm StagingPrednisoneRecurrenceRetrospective StudiesRituximabTreatment FailureTreatment OutcomeVincristineYoung AdultConceptsPrimary mediastinal large B-cell lymphomaDA-R-EPOCHDose-adjusted R-EPOCHNon-Hodgkin lymphomaB-cell lymphomaR-CHOPR-EPOCHMediastinal large B-cell lymphomaPrimary mediastinal B-cell lymphomaLarge B-cell lymphomaR-CHOP patientsComplete response rateMediastinal B-cell lymphomaTreatment-related complicationsPhase II trialProgression-free survivalR-CHOP chemotherapyTreatment-related toxicityUnique clinicopathological featuresMulti-center analysisII trialOverall survivalSecondary outcomesPrimary outcomeClinicopathological featuresPhysician volume and discontinuation of rituximab during lymphoma treatment.
Huntington S, Long J, Hoag J, Wang R, Zeidan A, Giri S, Gore S, Ma X, Gross C, Davidoff A. Physician volume and discontinuation of rituximab during lymphoma treatment. Journal Of Clinical Oncology 2017, 35: 6593-6593. DOI: 10.1200/jco.2017.35.15_suppl.6593.Peer-Reviewed Original ResearchNon-Hodgkin lymphomaEarly discontinuationRituximab discontinuationPhysician volumeProvider volumeEnd Results-Medicare dataB-cell non-Hodgkin lymphomaCell non-Hodgkin lymphomaCox proportional hazards modelDiscontinuation of rituximabSevere infusion reactionsRetrospective cohort studyImpact of discontinuationDays of initiationProportional hazards modelDose-dependent mannerRituximab cyclesRituximab initiationInfusion reactionsOverall survivalCohort studyPrimary outcomeSystemic treatmentLymphoma treatmentRelative risk