Identification and Partial Structural Characterization of Mass Isolated Valsartan and Its Metabolite with Messenger Tagging Vibrational Spectroscopy
Gorlova O, Colvin SM, Brathwaite A, Menges FS, Craig SM, Miller SJ, Johnson MA. Identification and Partial Structural Characterization of Mass Isolated Valsartan and Its Metabolite with Messenger Tagging Vibrational Spectroscopy. Journal Of The American Society For Mass Spectrometry 2017, 28: 2414-2422. PMID: 28801884, DOI: 10.1007/s13361-017-1767-z.Peer-Reviewed Original ResearchVibrational spectroscopyStructural characterizationRole of conformersOH stretching fundamentalsPartial structural characterizationStructural isomersIsomeric formsTarget ionsMass spectrometryN2 moleculesDrug valsartanRf ion trapIR absorptionIon trapFingerprint regionK ionsIon approachSpectroscopyIonsIsomersCharacterizationConformersRecent advancesSpectrometryOH