2017
A bottom up approach towards artificial oxygenases by combining iron coordination complexes and peptides
Cussó O, Giuliano MW, Ribas X, Miller SJ, Costas M. A bottom up approach towards artificial oxygenases by combining iron coordination complexes and peptides. Chemical Science 2017, 8: 3660-3667. PMID: 29270284, PMCID: PMC5734052, DOI: 10.1039/c7sc00099e.Peer-Reviewed Original ResearchIron centerHigh enantioselectivityIron coordination complexesAqueous hydrogen peroxideSecond coordination sphereΒ-turn structureShort reaction timesTerminal carboxylic acidSupramolecular catalystsCoordination complexesSupramolecular systemsClasses of substratesAsymmetric catalysisCoordination sphereAsymmetric epoxidationExcellent yieldsCarboxylic acidsCombination of peptidesActivation stepHydrogen peroxideReaction timeEpoxidationEnantioselectivityPeptidesCatalyst
2014
Experimental Lineage and Functional Analysis of a Remotely Directed Peptide Epoxidation Catalyst
Lichtor PA, Miller SJ. Experimental Lineage and Functional Analysis of a Remotely Directed Peptide Epoxidation Catalyst. Journal Of The American Chemical Society 2014, 136: 5301-5308. PMID: 24690108, PMCID: PMC4333582, DOI: 10.1021/ja410567a.Peer-Reviewed Original Research