2024
Fe/Thiol Cooperative Hydrogen Atom Transfer Olefin Hydrogenation: Mechanistic Insights That Inform Enantioselective Catalysis
Buzsaki S, Mason S, Kattamuri P, Serviano J, Rodriguez D, Wilson C, Hood D, Ellefsen J, Lu Y, Kan J, West J, Miller S, Holland P. Fe/Thiol Cooperative Hydrogen Atom Transfer Olefin Hydrogenation: Mechanistic Insights That Inform Enantioselective Catalysis. Journal Of The American Chemical Society 2024, 146: 17296-17310. PMID: 38875703, PMCID: PMC11209773, DOI: 10.1021/jacs.4c04047.Peer-Reviewed Original ResearchMetal-catalyzed hydrogen atom transferChiral thiolsAsymmetric hydrogenationSynthesis of complex moleculesMinimally functionalized olefinsSelectivity-determining stepTransition metal catalysisHydrogen atom transferOff-cycle speciesH-atom donorsTransfer of hydrideAsymmetric inductionElectron-richAtom transferMetal catalysisEnantioselective reductionThiol catalystMetal catalystsAlkyl radicalsElectron-neutralIron speciesOlefinsTraditional hydrogenationEnantiomeric ratioRadical catalysis
2016
Distal Stereocontrol Using Guanidinylated Peptides as Multifunctional Ligands: Desymmetrization of Diarylmethanes via Ullman Cross-Coupling
Kim B, Chinn AJ, Fandrick DR, Senanayake CH, Singer RA, Miller SJ. Distal Stereocontrol Using Guanidinylated Peptides as Multifunctional Ligands: Desymmetrization of Diarylmethanes via Ullman Cross-Coupling. Journal Of The American Chemical Society 2016, 138: 7939-7945. PMID: 27254785, PMCID: PMC5127171, DOI: 10.1021/jacs.6b03444.Peer-Reviewed Original Research