Combined Lewis acid and Brønsted acid-mediated reactivity of glycosyl trichloroacetimidate donors
Gould ND, Allen C, Nam BC, Schepartz A, Miller SJ. Combined Lewis acid and Brønsted acid-mediated reactivity of glycosyl trichloroacetimidate donors. Carbohydrate Research 2013, 382: 36-42. PMID: 24177201, DOI: 10.1016/j.carres.2013.09.011.Peer-Reviewed Original ResearchConceptsLewis acidGlycosylation reactionsCombined Lewis acidControl reactionsSubsequent kinetic studiesCatalytic systemBiomimetic conditionsCarboxylic acidsGlycosyl donorsIrreversible reactionKinetic studiesReactionAcid actsCatalytic componentAcidActive enzymeCarbohydrate-active enzymesCatalystProof of principleReactivityDonorsGlycosylStructure