2021
Benefits of a Multidisciplinary Women’s Sexual Health Clinic in the Management of Sexual and Menopausal Symptoms After Pelvic Radiotherapy
Li JY, D’Addario J, Tymon-Rosario J, Menderes G, Young MR, Johung K, Ratner E, Minkin MJ, Damast S. Benefits of a Multidisciplinary Women’s Sexual Health Clinic in the Management of Sexual and Menopausal Symptoms After Pelvic Radiotherapy. American Journal Of Clinical Oncology 2021, 44: 143-149. PMID: 33755031, DOI: 10.1097/coc.0000000000000800.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrachytherapyCombined Modality TherapyDyspareuniaFemaleGenital Neoplasms, FemaleHumansInterdisciplinary CommunicationMenopauseMiddle AgedPatient SatisfactionPelvisRadiation InjuriesRadiotherapyRectal NeoplasmsRetrospective StudiesSexual Dysfunction, PhysiologicalSexual HealthTreatment OutcomeVaginal DiseasesWomen's Health ServicesConceptsPelvic radiotherapySexual health clinicsMenopausal symptomsPersistent menopausal symptomsSystemic hormone therapyFemale cancer patientsPatterns of careDilator therapyVaginal estrogenGastrointestinal malignanciesHormone therapyVaginal drynessMedian ageMultidisciplinary careRetrospective reviewFemale patientsTreatment patternsCancer patientsPatient satisfactionSexual symptomsTestosterone creamVaginal lubricantsHealth clinicsSTATA 13.1Patients
2018
Extended duration of dilator use beyond 1 year may reduce vaginal stenosis after intravaginal high-dose-rate brachytherapy
Stahl JM, Qian JM, Tien CJ, Carlson DJ, Chen Z, Ratner ES, Park HS, Damast S. Extended duration of dilator use beyond 1 year may reduce vaginal stenosis after intravaginal high-dose-rate brachytherapy. Supportive Care In Cancer 2018, 27: 1425-1433. PMID: 30187220, DOI: 10.1007/s00520-018-4441-5.Peer-Reviewed Original ResearchConceptsVaginal stenosisEndometrial carcinomaMultivariable Cox proportional hazardsMultivariable Cox regression analysisVD useAcademic tertiary referral centerTertiary referral centerCox regression analysisLog-rank testCox proportional hazardsDevelopment of gradeDilator usePelvic radiotherapyReferral centerNoncompliant patientsPrimary outcomeAdjuvant brachytherapyEC patientsConclusionsThe riskRate brachytherapyProportional hazardsOptimal durationPatientsBrachytherapyStudy period
2017
Impact of vaginal cylinder diameter on outcomes following brachytherapy for early stage endometrial cancer
Qian JM, Stahl JM, Young MR, Ratner E, Damast S. Impact of vaginal cylinder diameter on outcomes following brachytherapy for early stage endometrial cancer. Journal Of Gynecologic Oncology 2017, 28: 0. PMID: 29027402, PMCID: PMC5641534, DOI: 10.3802/jgo.2017.28.e84.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdultAgedAged, 80 and overBody Mass IndexBrachytherapyConstriction, PathologicDatabases, FactualEndometrial NeoplasmsFemaleGastrointestinal DiseasesGravidityHumansHysterectomyLymph Node ExcisionMiddle AgedNeoplasm StagingOvariectomyRadiation InjuriesRadiotherapy, AdjuvantSalpingectomyTreatment OutcomeVaginaVaginal DiseasesConceptsVaginal brachytherapyVaginal symptomsLate grade 3 toxicityEarly-stage endometrial cancerNormal body mass indexAdjuvant vaginal brachytherapyGrade 3 toxicityShorter vaginal lengthStage endometrial cancerEndometrial cancer patientsBody mass indexRate of recurrenceAcute gastrointestinalTreatment tolerabilityVaginal stenosisEndometrial cancerVaginal lengthMass indexRecurrence rateCancer patientsVaginal toxicityTreatment characteristicsHigh riskSide effectsPatients
2012
Sexual Functioning Among Endometrial Cancer Patients Treated With Adjuvant High-Dose-Rate Intra-Vaginal Radiation Therapy
Damast S, Alektiar KM, Goldfarb S, Eaton A, Patil S, Mosenkis J, Bennett A, Atkinson T, Jewell E, Leitao M, Barakat R, Carter J, Basch E. Sexual Functioning Among Endometrial Cancer Patients Treated With Adjuvant High-Dose-Rate Intra-Vaginal Radiation Therapy. International Journal Of Radiation Oncology • Biology • Physics 2012, 84: e187-e193. PMID: 22572074, PMCID: PMC5538259, DOI: 10.1016/j.ijrobp.2012.03.030.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, IntravaginalAdolescentAdultAgedAged, 80 and overBrachytherapyCross-Sectional StudiesDehydrationDilatationEndometrial NeoplasmsFemaleHumansHysterectomyLaparotomyLibidoMiddle AgedOrgasmPainPersonal SatisfactionRadiotherapy DosageRadiotherapy, AdjuvantReference ValuesRegression AnalysisRisk FactorsSexual Dysfunction, PhysiologicalSurveys and QuestionnairesVaginal Creams, Foams, and JelliesVaginal DiseasesYoung AdultConceptsFemale Sexual Function IndexEndometrial cancer patientsSexual dysfunctionFSFI scoreSexual functioningCancer patientsEarly stage endometrial cancer patientsQuestionnaire completionRates of SDLubricant useLower FSFI scoresSexual Function IndexPoor sexual functioningRadiation oncology clinicPostmenopausal statusSimple hysterectomyPostmenopausal populationOncology clinicAdjuvant brachytherapyEC patientsRisk factorsFunction IndexRadiation therapyHigh doseMultivariate analysis