2024
Premature mortality trends in 183 countries by cancer type, sex, WHO region, and World Bank income level in 2000–19: a retrospective, cross-sectional, population-based study
Murthy S, Trapani D, Cao B, Bray F, Murthy S, Kingham T, Are C, Ilbawi A. Premature mortality trends in 183 countries by cancer type, sex, WHO region, and World Bank income level in 2000–19: a retrospective, cross-sectional, population-based study. The Lancet Oncology 2024, 25: 969-978. PMID: 38964357, PMCID: PMC11329430, DOI: 10.1016/s1470-2045(24)00274-2.Peer-Reviewed Original ResearchPremature mortality ratesWorld Bank income levelsNon-communicable diseasesPremature mortalityLow-income countriesHigh-income countriesWHO regionsMortality trendsRising burden of non-communicable diseasesBurden of non-communicable diseasesRisk of premature mortalityMortality rateIncome levelWorld Bank income groupsPrimary prevention programmesStandard life table methodsColorectal cancerPopulation-based studyPrimary prevention measuresAnnual rateEarly detection strategiesCancer typesAnnual rate of changeIndividual cancer typesSex-related disparitiesPolicy strategies for capacity building and scale up of the workforce for comprehensive cancer care: a systematic review
Trapani D, Murthy S, Hammad N, Casolino R, Moreira D, Roitberg F, Blay J, Curigliano G, Ilbawi A. Policy strategies for capacity building and scale up of the workforce for comprehensive cancer care: a systematic review. ESMO Open 2024, 9: 102946. PMID: 38507895, PMCID: PMC10966170, DOI: 10.1016/j.esmoop.2024.102946.Peer-Reviewed Original ResearchConceptsComprehensive cancer careCancer careSystematic reviewHealth systemCapacity buildingCancer care providersCapacity of health systemsDigital health interventionsWorkforce capacity buildingMiddle-income countriesHigh-income countriesResource-constrained settingsCancer workforceHealth workforceOncology providersCare providersWorkforce interventionsUnderserved areasHealth interventionsWorkforce strategiesCompetent workforceCareIncreased workloadData extractionWorkforce
2023
Cancer surgery on the global stage: Updates and progress
Murthy S, Are C. Cancer surgery on the global stage: Updates and progress. Journal Of Surgical Oncology 2023, 129: 145-149. PMID: 38059658, DOI: 10.1002/jso.27548.Peer-Reviewed Original ResearchGlobal Cancer Surgery: pragmatic solutions to improve cancer surgery outcomes worldwide.
Are C, Murthy SS, Sullivan R, Schissel M, Chowdhury S, Alatise O, Anaya D, Are M, Balch C, Bartlett D, Brennan M, Cairncross L, Clark M, Deo SVS, Dudeja V, D'Ugo D, Fadhil I, Giuliano A, Gopal S, Gutnik L, Ilbawi A, Jani P, Kingham P, Lorenzon L, Leiphrakpam P, Leon A, Martinez-Said H, McMasters K, Meltzer DO, Mutebi M, Nabeel Z, Naik V, Newman L, Oliveira AF, Park DJ, Pramesh CS, Rao S, Subramanyeshwar Rao T, Rocha Bargallo E, Romanoff A, Rositch AF, Rubio I, Salvador de Castro Ribeiro H, Sbaity E, Senthil M, Smith L, Toi M, Turaga K, Yanala U, Yip CH, Zaghloul A, Anderson BO. Global Cancer Surgery: pragmatic solutions to improve cancer surgery outcomes worldwide. Lancet Oncol 2023 PMID: 37924819, DOI: 10.1016/S1470-2045(23)00412-6.Peer-Reviewed Original ResearchEducation of the cancer surgical workforce: Gaps, priorities, and strategies
Murthy S, Are C. Education of the cancer surgical workforce: Gaps, priorities, and strategies. Journal Of Surgical Oncology 2023, 128: 938-942. PMID: 37818912, DOI: 10.1002/jso.27443.Peer-Reviewed Original ResearchInequities in cancer surgical research capacity in the global south and strategies to address them
Murthy S, Are C. Inequities in cancer surgical research capacity in the global south and strategies to address them. Journal Of Surgical Oncology 2023, 128: 947-951. PMID: 37804090, DOI: 10.1002/jso.27446.Peer-Reviewed Original ResearchClinical and oncological outcomes of pelvic exenteration surgery for anal squamous cell carcinoma.
Quyn AJ, Murthy S, Gould L, Said H, Tiernan J, Sagar P, Antoniou A, Jenkins I, Burns EM. Clinical and oncological outcomes of pelvic exenteration surgery for anal squamous cell carcinoma. Colorectal Dis 2023 PMID: 37753947, DOI: 10.1111/codi.16736.Peer-Reviewed Original ResearchColorectal cancer: Review of signaling pathways and associated therapeutic strategies
Leiphrakpam P, Rajappa S, Krishnan M, Batra R, Murthy S, Are C. Colorectal cancer: Review of signaling pathways and associated therapeutic strategies. Journal Of Surgical Oncology 2023, 127: 1277-1295. PMID: 37222698, DOI: 10.1002/jso.27295.Peer-Reviewed Original Research
2022
The effect of social determinants of health on utilization of surgical treatment for hepatocellular carcinoma patients
Murthy S, Ortiz A, DuBois T, Sorice K, Nguyen M, Castellanos J, Pinheiro P, Gonzalez E, Lynch S. The effect of social determinants of health on utilization of surgical treatment for hepatocellular carcinoma patients. The American Journal Of Surgery 2022, 225: 715-723. PMID: 36344305, DOI: 10.1016/j.amjsurg.2022.10.011.Peer-Reviewed Original ResearchConceptsStage I patientsHepatocellular carcinomaI patientsSocial determinantsOdds of surgeryReceipt of surgeryHepatocellular carcinoma patientsMultilevel logistic regression modelsPaucity of dataLogistic regression modelsCarcinoma patientsSurgical treatmentBlack patientsCancer RegistryCancer outcomesHCC patientsSDOH domainsSDoH variablesInfluence treatmentLower oddsPatientsSurgeryHealthcare professionalsSDOHInsurance access
2021
Distribution of the workforce involved in cancer care: a systematic review of the literature ☆
Trapani D, Murthy S, Boniol M, Booth C, Simensen V, Kasumba M, Giuliani R, Curigliano G, Ilbawi A. Distribution of the workforce involved in cancer care: a systematic review of the literature ☆. ESMO Open 2021, 6: 100292. PMID: 34763251, PMCID: PMC8591344, DOI: 10.1016/j.esmoop.2021.100292.Peer-Reviewed Original ResearchConceptsCancer careSystematic reviewHigh-income countriesHealth providersMultidisciplinary cancer careMultidisciplinary cancer managementSkilled health workforceCross-sectional surveyPaucity of dataHealth care workforcePaucity of literatureFirst systematic reviewCancer nursesCancer patientsPediatric oncologySurgical oncologyHealth workersWorkforce densityCancer managementEligible papersCancer workforceHealth workforceHealth systemCare workforceWorkforce capacity
2020
A Randomized Cross-Over Trial Focused on Clinical Breast Exam Skill Acquisition Using High Fidelity versus Low Fidelity Simulation Models in Rwanda
Murthy S, Ntakiyiruta G, Ntirenganya F, Ingabire A, Defregger S, Reznor G, Lipitz S, Troyan S, Raza S, Dunnington G, Riviello R. A Randomized Cross-Over Trial Focused on Clinical Breast Exam Skill Acquisition Using High Fidelity versus Low Fidelity Simulation Models in Rwanda. Journal Of Surgical Education 2020, 77: 1161-1168. PMID: 32241670, DOI: 10.1016/j.jsurg.2020.02.030.Peer-Reviewed Original ResearchConceptsClinical breast examMean differenceRandomized cross-over trialBreast cancer incidenceCross-over trialUniversity Teaching HospitalSimulation training courseHealth care workforceInternal medicine residentsSecondary outcomesPrimary outcomeMiddle-income countriesCrossover trialBreast examBaseline examCancer incidenceResource-poor areasTeaching hospitalBreast cancerLF groupCare workforceExam 1Medicine residentsScoresIncome countriesA Randomized Cross-Over Trial Focused on Breast Core Needle Biopsy Skill Acquisition and Safety Using High Fidelity Versus Low Fidelity Simulation Models in Rwanda
Murthy S, Ntirenganya F, Scott J, Ingabire A, Rosman D, Raza S, Troyan S, Dunnington G, Reznor G, Lipitz S, Ntakiyiruta G, Riviello R. A Randomized Cross-Over Trial Focused on Breast Core Needle Biopsy Skill Acquisition and Safety Using High Fidelity Versus Low Fidelity Simulation Models in Rwanda. Journal Of Surgical Education 2020, 77: 404-412. PMID: 31902690, DOI: 10.1016/j.jsurg.2019.11.014.Peer-Reviewed Original ResearchConceptsBreast core needle biopsyLF groupRandomized cross-over trialMean differenceDiagnostic surgical proceduresCross-over trialUniversity Teaching HospitalCore needle biopsyHealth care personnelHF armMiddle-income countriesCrossover trialCommon cancerBaseline examNeedle biopsyTeaching hospitalBreast cancerSurgical proceduresCare personnelDiagnostic proceduresSimulation training courseResident trainingCancerScoresSkill acquisition
2018
Teaching surgical skills in a resource-limited setting: Comparing massed versus distributed practice in an ultrasound-guided breast biopsy simulator
Munyaneza R, Martin A, Riviello R, Abahuje E, Murthy S, Ntirenganya F. Teaching surgical skills in a resource-limited setting: Comparing massed versus distributed practice in an ultrasound-guided breast biopsy simulator. East And Central African Journal Of Surgery 2018, 23: 89-94. DOI: 10.4314/ecajs.v23i3.1.Peer-Reviewed Original ResearchFinal year medical studentsSurgical skillsOptimal teaching methodologyBreast simulatorSkill retentionYear medical studentsFirst-year residentsTeaching methodologyPosttest resultsMedical studentsProcedural skillsSimulation labSkill acquisitionSkillsSimulation trainingPretestTrainingLogistical resourcesTraineesPractice scheduleGlobal surgeryPracticeTeachingStudentsSettingThe Cost of Complications Following Major Resection of Malignant Neoplasia
Zogg CK, Ottesen TD, Kebaish KJ, Galivanche A, Murthy S, Changoor NR, Zogg DL, Pawlik TM, Haider AH. The Cost of Complications Following Major Resection of Malignant Neoplasia. Journal Of Gastrointestinal Surgery 2018, 22: 1976-1986. PMID: 29946953, PMCID: PMC6224301, DOI: 10.1007/s11605-018-3850-6.Peer-Reviewed Original ResearchConceptsIncremental hospital costsHospital costsMalignant neoplasiaMajor resectionResection typePre-discharge complicationsSystem-based complicationsImpact of complicationsComplex surgical patientsCost of complicationsLong-term treatmentMore complex patientsMajor gastrointestinal resectionsProviders/payersValue of carePulmonary complicationsUrinary complicationsComplication groupInfectious complicationsAdult patientsRectal resectionSurgical patientsGastrointestinal resectionGI diseaseSurgical outcomes
2017
Association of Insurance Expansion With Surgical Management of Thyroid Cancer
Loehrer A, Murthy S, Song Z, Lubitz C, James B. Association of Insurance Expansion With Surgical Management of Thyroid Cancer. JAMA Surgery 2017, 152: 734-740. PMID: 28384780, PMCID: PMC5831462, DOI: 10.1001/jamasurg.2017.0461.Peer-Reviewed Original Research
2015
A national framework for breast cancer control: A report on Rwanda’s inaugural symposium on the management of breast cancer
Murthy S, Tapela N, Muhimpundu M, Balinda J, Musabyemariya F, Kirby K, Pace L, Riviello R, Ntirenganya F, Ntakiyiruta G. A national framework for breast cancer control: A report on Rwanda’s inaugural symposium on the management of breast cancer. Journal Of Cancer Policy 2015, 6: 3-7. DOI: 10.1016/j.jcpo.2015.08.004.Peer-Reviewed Original ResearchBreast cancerHealth care systemBreast cancer control programsCare systemCancer-related mortalityCancer control programsBreast cancer controlHealth care providersPatient-centered careMinistry of HealthSurvivable cancersMiddle-income countriesClinical outcomesBC patientsLeading causeCancer controlHigh-income countriesCare providersCare deliveryCancerInaugural symposiumCareControl programsOutcomesMulti-disciplinary collaborationStandard of care versus second-best: Ethical dilemmas in surgery for high risk papillary thyroid cancer in low and middle-income countries
Murthy S, Eyal N, Norheim O, Ruan D, Ntakiyiruta G, Robert R. Standard of care versus second-best: Ethical dilemmas in surgery for high risk papillary thyroid cancer in low and middle-income countries. Journal Of Cancer Policy 2015, 6: 8-10. DOI: 10.1016/j.jcpo.2015.08.006.Peer-Reviewed Original ResearchA Randomized Control Trial Focused on Breast Core Needle Biopsy Skill Acquisition Using High Fidelity vs Low Fidelity Simulation Models in Rwanda: A Baseline Analysis
Murthy S, Riviello R, Dunnington G, Rosman D, Raza S, Troyan S, Ntakiyiruta G. A Randomized Control Trial Focused on Breast Core Needle Biopsy Skill Acquisition Using High Fidelity vs Low Fidelity Simulation Models in Rwanda: A Baseline Analysis. Journal Of The American College Of Surgeons 2015, 221: s86. DOI: 10.1016/j.jamcollsurg.2015.07.194.Peer-Reviewed Original ResearchGlobal cancer surgery: delivering safe, affordable, and timely cancer surgery
Sullivan R, Alatise O, Anderson B, Audisio R, Autier P, Aggarwal A, Balch C, Brennan M, Dare A, D'Cruz A, Eggermont A, Fleming K, Gueye S, Hagander L, Herrera C, Holmer H, Ilbawi A, Jarnheimer A, Ji J, Kingham T, Liberman J, Leather A, Meara J, Mukhopadhyay S, Murthy S, Omar S, Parham G, Pramesh C, Riviello R, Rodin D, Santini L, Shrikhande S, Shrime M, Thomas R, Tsunoda A, van de Velde C, Veronesi U, Vijaykumar D, Watters D, Wang S, Wu Y, Zeiton M, Purushotham A. Global cancer surgery: delivering safe, affordable, and timely cancer surgery. The Lancet Oncology 2015, 16: 1193-1224. PMID: 26427363, DOI: 10.1016/s1470-2045(15)00223-5.Peer-Reviewed Original Research
2014
Dual eligible beneficiaries: roles for surgeons under health care reform.
Murthy S, Weissman J, Grabowski D, McDonald K, Kaups K, Meara J. Dual eligible beneficiaries: roles for surgeons under health care reform. Bulletin Of The American College Of Surgeons 2014, 99: 10-9. PMID: 24783702.Peer-Reviewed Original Research