In silico model development and optimization of in vitro lung cell population growth
Mostofinejad A, Romero D, Brinson D, Marin-Araujo A, Bazylak A, Waddell T, Haykal S, Karoubi G, Amon C. In silico model development and optimization of in vitro lung cell population growth. PLOS ONE 2024, 19: e0300902. PMID: 38748626, PMCID: PMC11095723, DOI: 10.1371/journal.pone.0300902.Peer-Reviewed Original ResearchMeSH KeywordsCell LineCell ProliferationComputer SimulationEpithelial CellsGlucoseHumansLungModels, BiologicalOxygenTissue EngineeringBioengineering of vascularized porcine flaps using perfusion-recellularization
Xu M, D’Elia A, Hadzimustafic N, Adil A, Karoubi G, Waddell T, Haykal S. Bioengineering of vascularized porcine flaps using perfusion-recellularization. Scientific Reports 2024, 14: 7590. PMID: 38555385, PMCID: PMC10981729, DOI: 10.1038/s41598-024-58095-7.Peer-Reviewed Original ResearchConceptsLow-concentration sodium dodecyl sulfateAcellular scaffoldsRecellularization techniquesPerfusion-decellularizationMesenchymal stromal cellsSodium dodecyl sulfateCell attachmentRecellularization approachCo-culture of human umbilical vein endothelial cellsRecellularizationHuman umbilical vein endothelial cellsReconstructive surgeryTensor fasciae lataeExtracellular matrixRepair optionsDonor site morbidityImpact patient qualityDodecyl sulfateClinically translatable optionTensor fascia lata flapUmbilical vein endothelial cellsSoft tissue defectsPorcine flaps