2022
864-P: Glycemic Control across eGFR Categories with the Dual SGLT1 and 2 Inhibitor Sotagliflozin in SCORED
INZUCCHI S, BHATT D, PITT B, SZAREK M, CANNON C, LEWIS J, RIDDLE M, KOSIBOROD M, CHERNEY D, DWYER J, SCIRICA B, BAILEY C, BANKS P, DIAZ R, RAY K, UDELL J, LOPES R, LEITER L, STEG P. 864-P: Glycemic Control across eGFR Categories with the Dual SGLT1 and 2 Inhibitor Sotagliflozin in SCORED. Diabetes 2022, 71 DOI: 10.2337/db22-864-p.Peer-Reviewed Original ResearchGlucose-lowering medicationsPre-specified subgroupsNovartis Pharmaceuticals CorporationGlaxoSmithKline plcDaiichi SankyoDual SGLT1Baseline A1CBaseline eGFRPfizer Inc.Bristol-Myers Squibb CompanyLexicon PharmaceuticalsOutcome trialsCSL BehringNovo NordiskNovartis AGAdvanced chronic kidney diseaseType 2 diabetes patientsEli LillyAmgen Inc.Lower baseline eGFROverall trial populationCKD stage 4Primary composite outcomeSpeakers bureauCardiovascular outcome trials
2020
380-P: Hypoglycemia among Nursing Home Residents with Diabetes Detected by Continuous Glucose Monitoring (CGM)
LIPSKA K, DOYLE M, CENGIZ E, DROZDOWICZ B, GILL T, MURPHY T, INZUCCHI S. 380-P: Hypoglycemia among Nursing Home Residents with Diabetes Detected by Continuous Glucose Monitoring (CGM). Diabetes 2020, 69 DOI: 10.2337/db20-380-p.Peer-Reviewed Original ResearchContinuous glucose monitoringNursing home residentsHome residentsNursing homesConsecutive blood glucose levelsFlash continuous glucose monitoringPatients 65 yearsChronic kidney diseaseFrequency of hypoglycemiaLexicon PharmaceuticalsType 2 diabetesBlood glucose levelsWilcoxon rank sum testRank sum testMannKind CorporationAdvisory PanelConnecticut nursing homesADL disabilityMedian ageKidney diseaseNovo Nordisk A/SCGM periodGlucose levelsHypoglycemiaLong-term residents23-OR: EHR-Based Blood Glucose Alerts Improve Inpatient Glycemic Control at a Large Academic Medical Center
BAK L, FANDEL T, BOZZO J, DEWITT M, CHEN P, PANDO R, FERRO L, KAPLAN R, HENDRICKSON K, AMPORT S, SUSSMAN L, INZUCCHI S. 23-OR: EHR-Based Blood Glucose Alerts Improve Inpatient Glycemic Control at a Large Academic Medical Center. Diabetes 2020, 69 DOI: 10.2337/db20-23-or.Peer-Reviewed Original ResearchAcademic medical centerLarge academic medical centerMedical CenterBG controlEHR-based interventionsInsulin order setsNon-ICU wardsBlood glucose managementInpatient glycemic controlElectronic health recordsControl wardsGlycemic controlSignificant hyperglycemiaNovo Nordisk A/SGlucose managementScore 2Severe hyperIndividual wardsControl groupOrder setsWardsHealth recordsLexicon PharmaceuticalsBG managementHypoglycemia927-P: Effect of Oral Semaglutide with or without Background SGLT2i in Patients with T2D: Subgroup Analysis of PIONEER 4
PRATLEY R, BAUER R, INZUCCHI S, KHUNTI K, KREINER E, LAURSEN P, MEIER J. 927-P: Effect of Oral Semaglutide with or without Background SGLT2i in Patients with T2D: Subgroup Analysis of PIONEER 4. Diabetes 2020, 69 DOI: 10.2337/db20-927-p.Peer-Reviewed Original ResearchNovo Nordisk A/SDohme Corp.Oral semaglutideMerck SharpGLP-1RAsSanofi-AventisNovartis AGRoche PharmaSGLT2 inhibitorsSubgroup analysisEli LillyGlucagon-like peptide-1 receptor agonistsPeptide-1 receptor agonistsDaily oral semaglutideTrial product estimandGastrointestinal adverse eventsLexicon PharmaceuticalsSubgroup of patientsJanssen Scientific AffairsType 2 diabetesBayer AGBoehringer Ingelheim PharmaceuticalsAdvisory PanelSubcutaneous liraglutideT2D duration
2018
Empagliflozin (EMPA) Reduces Mortality and Hospitalization for Heart Failure (HHF) Irrespective of Cardiovascular (CV) Risk Score at Baseline
FITCHETT D, SCIRICA B, INZUCCHI S, CANNON C, MCGUIRE D, JOHANSEN O, SAMBEVSKI S, HEHNKE U, GEORGE J, ZINMAN B. Empagliflozin (EMPA) Reduces Mortality and Hospitalization for Heart Failure (HHF) Irrespective of Cardiovascular (CV) Risk Score at Baseline. Diabetes 2018, 67 DOI: 10.2337/db18-1123-p.Peer-Reviewed Original ResearchEMPA-REG OUTCOME trialBoehringer Ingelheim PharmaceuticalsBaseline CV riskCV deathProportion of patientsCause deathEisai Inc.CV riskOutcome trialsRisk scoreJanssen PharmaceuticalsGlaxoSmithKline plcBristol-Myers Squibb CompanyNovo Nordisk A/SLexicon PharmaceuticalsEli LillyBenefits of empagliflozinBoehringer Ingelheim GmbHResidual CV riskEffect of empagliflozinTIMI risk scorePfizer Inc.Sanofi-AventisCardiovascular risk scoreAmgen Inc.