2010
Telomere-independent Rap1 is an IKK adaptor and regulates NF-κB-dependent gene expression
Teo H, Ghosh S, Luesch H, Ghosh A, Wong ET, Malik N, Orth A, de Jesus P, Perry AS, Oliver JD, Tran NL, Speiser LJ, Wong M, Saez E, Schultz P, Chanda SK, Verma IM, Tergaonkar V. Telomere-independent Rap1 is an IKK adaptor and regulates NF-κB-dependent gene expression. Nature Cell Biology 2010, 12: 758-767. PMID: 20622870, DOI: 10.1038/ncb2080.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsApoptosisBlotting, WesternCell LineCell Line, TumorChromatin ImmunoprecipitationChromatography, GelHeLa CellsHumansI-kappa B KinaseImmunohistochemistryImmunoprecipitationKaplan-Meier EstimateMiceNF-kappa BPhosphorylationPolymerase Chain ReactionProtein BindingRNA, Small InterferingShelterin ComplexTelomere-Binding ProteinsTissue Array Analysis
2003
Mitotic Regulation of Ribosomal S6 Kinase 1 Involves Ser/Thr, Pro Phosphorylation of Consensus and Non-consensus Sites by Cdc2*
Shah OJ, Ghosh S, Hunter T. Mitotic Regulation of Ribosomal S6 Kinase 1 Involves Ser/Thr, Pro Phosphorylation of Consensus and Non-consensus Sites by Cdc2*. Journal Of Biological Chemistry 2003, 278: 16433-16442. PMID: 12586835, DOI: 10.1074/jbc.m300435200.Peer-Reviewed Original ResearchConceptsSer/ThrMultiple Ser/ThrRibosomal S6 kinase 1Hydrophobic motif siteRibosomal protein mRNAsRNA polymerase IIProline-directed phosphorylationRibosomal protein synthesisPhosphorylation of S6K1S6 kinase 1Mitotic HeLa cellsCyclin-dependent kinasesActivity of cdc2Elongation factor 1gammaNon-consensus sitesRibosome biogenesisMitotic regulationPolymerase IIPhosphorylation sitesMRNA processingMotif sitesProtein kinaseTriggers inactivationMitotic processesCyclin B