2018
137 Safety of Second Round of Eight Injections of Collagenase Clostridium Histolyticum (CCH) in the Treatment of Peyronie's Disease
Bryson C, Xu I, Honig S. 137 Safety of Second Round of Eight Injections of Collagenase Clostridium Histolyticum (CCH) in the Treatment of Peyronie's Disease. The Journal Of Sexual Medicine 2018, 15: s35-s36. DOI: 10.1016/j.jsxm.2017.11.095.Peer-Reviewed Original Research
2015
Analysis of the clinical safety of intralesional injection of collagenase Clostridium histolyticum (CCH) for adults with Peyronie's disease (PD)
Carson CC, Sadeghi-Nejad H, Tursi JP, Smith TM, Kaufman GJ, Gilbert K, Honig SC. Analysis of the clinical safety of intralesional injection of collagenase Clostridium histolyticum (CCH) for adults with Peyronie's disease (PD). BJU International 2015, 116: 815-822. PMID: 25818264, DOI: 10.1111/bju.13120.Peer-Reviewed Original ResearchConceptsTreatment-related adverse eventsCollagenase clostridium histolyticumPooled safety analysisAdverse eventsSerious AEsPeyronie's diseasePenile haematomaIntralesional injectionClinical studiesSerious treatment-related adverse eventsTreatment-emergent adverse eventsTreatment-related serious AEsOpen-label safetyPlacebo-controlled studySerious adverse eventsSystemic hypersensitivity reactionClostridium histolyticumCorporal ruptureHypersensitivity eventsPenile painMost patientsPenile swellingAntibody levelsCCH treatmentHypersensitivity reactions134 Peyronie's disease symptom bother reduction is related to penile curvature improvement in response to treatment with collagenase clostridium histolyticum: Results from two large double-blind, randomized, placebo-controlled phase 3 studies
Lipshultz L, Sadeghi-Nejad H, Mills J, Tursi J, Smith T, Kaufman G, Liu G, Honig S. 134 Peyronie's disease symptom bother reduction is related to penile curvature improvement in response to treatment with collagenase clostridium histolyticum: Results from two large double-blind, randomized, placebo-controlled phase 3 studies. European Urology Open Science 2015, 14: e134. DOI: 10.1016/s1569-9056(15)60136-1.Peer-Reviewed Original ResearchPlacebo-controlled phase 3 studyPhase 3 studyCollagenase clostridium histolyticumCurvature improvementClostridium histolyticum