2022
Two-Year Analysis of a New Oral Testosterone Undecanoate (TU) Formulation in Hypogonadal Men: Efficacy, Impact on Psychosexual Function, and Safety.
Honig S, Gittelman M, Kaminetsky J, Wang C, Amory J, Rohowsky N, Dudley R, Woun Seo B, Newmark J, Swerdloff R. Two-Year Analysis of a New Oral Testosterone Undecanoate (TU) Formulation in Hypogonadal Men: Efficacy, Impact on Psychosexual Function, and Safety. The Journal Of Sexual Medicine 2022, 19: 1750-1758. PMID: 37057401, DOI: 10.1016/j.jsxm.2022.09.002.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedHumansHypogonadismLibidoMaleMiddle AgedSexual BehaviorTestosteroneYoung AdultConceptsTestosterone replacement therapyPsychosexual Daily QuestionnaireLiver function testsOral TUSerum T concentrationsSexual functionT concentrationsTU therapyHypogonadal menFunction testsEffective long-term treatment optionProstate-specific antigen levelHigh-density lipoprotein cholesterolLong-term treatment optionAdult hypogonadal menOral testosterone undecanoateTotal testosterone levelsSystolic blood pressureTotal T concentrationsActive-controlled trialYears of treatmentLong-term safetySignificant changesEugonadal rangeCardiovascular endpoints
2016
Trends in Testosterone Replacement Therapy Use from 2003 to 2013 among Reproductive-Age Men in the United States
Rao PK, Boulet SL, Mehta A, Hotaling J, Eisenberg ML, Honig SC, Warner L, Kissin DM, Nangia AK, Ross LS. Trends in Testosterone Replacement Therapy Use from 2003 to 2013 among Reproductive-Age Men in the United States. Journal Of Urology 2016, 197: 1121-1126. PMID: 27789218, PMCID: PMC11056957, DOI: 10.1016/j.juro.2016.10.063.Peer-Reviewed Original ResearchConceptsTherapy useReproductive-age menTherapy usersMen 18Older menTestosterone replacement therapyTruven Health MarketScanLong-term sequelaeCommercial claims databaseYounger age groupsCochran-Armitage testCross-sectional analysisFourfold increaseMen 56Topical gel formulationTestosterone useClaims databaseReplacement therapySignificant threefold increaseInjection usePractice patternsGel usePoisson regressionAge groupsSemen analysis