2015
Analysis of the clinical safety of intralesional injection of collagenase Clostridium histolyticum (CCH) for adults with Peyronie's disease (PD)
Carson CC, Sadeghi-Nejad H, Tursi JP, Smith TM, Kaufman GJ, Gilbert K, Honig SC. Analysis of the clinical safety of intralesional injection of collagenase Clostridium histolyticum (CCH) for adults with Peyronie's disease (PD). BJU International 2015, 116: 815-822. PMID: 25818264, DOI: 10.1111/bju.13120.Peer-Reviewed Original ResearchConceptsTreatment-related adverse eventsCollagenase clostridium histolyticumPooled safety analysisAdverse eventsSerious AEsPeyronie's diseasePenile haematomaIntralesional injectionClinical studiesSerious treatment-related adverse eventsTreatment-emergent adverse eventsTreatment-related serious AEsOpen-label safetyPlacebo-controlled studySerious adverse eventsSystemic hypersensitivity reactionClostridium histolyticumCorporal ruptureHypersensitivity eventsPenile painMost patientsPenile swellingAntibody levelsCCH treatmentHypersensitivity reactions
2005
Herniorrhaphy With Polypropylene Mesh Causing Inguinal Vasal Obstruction
Shin D, Lipshultz LI, Goldstein M, Barmé GA, Fuchs EF, Nagler HM, McCallum SW, Niederberger CS, Schoor RA, Brugh VM, Honig SC. Herniorrhaphy With Polypropylene Mesh Causing Inguinal Vasal Obstruction. Annals Of Surgery 2005, 241: 553-558. PMID: 15798455, PMCID: PMC1357057, DOI: 10.1097/01.sla.0000157318.13975.2a.Peer-Reviewed Original ResearchConceptsInguinal hernia repairPolypropylene meshVasal obstructionHernia repairMesh herniorrhaphyContralateral testicular atrophyFibroblastic responseInguinal hernia operationsCases of azoospermiaYoung reproductive ageSolitary testicleBilateral obstructionUrologic evaluationPatient agePatient characteristicsOperative findingsSurgical explorationUnilateral obstructionMultiinstitutional experienceTesticular atrophyEpididymal obstructionFuture fertilityReproductive ageSurgical reconstructionLong-term effects