2018
Surveillance of Maternal Syphilis in China: Pregnancy Outcomes and Determinants of Congenital Syphilis
Zhang X, Yu Y, Yang H, Xu H, Vermund SH, Liu K. Surveillance of Maternal Syphilis in China: Pregnancy Outcomes and Determinants of Congenital Syphilis. Medical Science Monitor 2018, 24: 7727-7735. PMID: 30370903, PMCID: PMC6216479, DOI: 10.12659/msm.910216.Peer-Reviewed Original ResearchConceptsAdverse pregnancy outcomesPregnancy outcomesCongenital syphilisPregnant womenFirst antenatal care visitEligible pregnant womenPrevention of motherAntenatal care visitsIndependent risk factorMultivariable regression analysisLogistic regression analysisRegression analysisChild transmissionMaternal syphilisAntenatal careCare visitsNeonatal asphyxiaNeonatal deathFirst trimesterRisk womenAntibody titersAntenatal testingEpidemiological characteristicsRisk factorsSyphilis diagnosisPartners-based HIV treatment for seroconcordant couples attending antenatal and postnatal care in rural Mozambique: A cluster randomized trial protocol
Audet CM, Graves E, Barreto E, De Schacht C, Gong W, Shepherd BE, Aboobacar A, Gonzalez-Calvo L, Alvim MF, Aliyu MH, Kipp AM, Jordan H, Amico KR, Diemer M, Ciaranello A, Dugdale C, Vermund SH, Van Rompaey S. Partners-based HIV treatment for seroconcordant couples attending antenatal and postnatal care in rural Mozambique: A cluster randomized trial protocol. Contemporary Clinical Trials 2018, 71: 63-69. PMID: 29879469, PMCID: PMC6067957, DOI: 10.1016/j.cct.2018.05.020.Peer-Reviewed Original ResearchConceptsChild transmissionSeroconcordant couplesMale partnersResource-limited rural settingsElimination of motherRoutine clinical dataUptake of servicesClinical trial designMale partner approvalAntiretroviral therapyHIV careAntenatal careRural MozambiqueHIV servicesPostnatal carePregnant womenHIV treatmentTrial protocolClinical dataHealth facilitiesTrial designHIVNewborn childrenPartner approvalEngagement interventions
2016
Patient and Provider Satisfaction With a Comprehensive Strategy to Improve Prevention of Mother-to-Child HIV Transmission Services in Rural Nigeria
Boehmer A, Audet CM, Blevins M, Gebi UI, Wester CW, Vermund SH, Aliyu MH. Patient and Provider Satisfaction With a Comprehensive Strategy to Improve Prevention of Mother-to-Child HIV Transmission Services in Rural Nigeria. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2016, 72: s117-s123. PMID: 27355498, PMCID: PMC5113240, DOI: 10.1097/qai.0000000000001058.Peer-Reviewed Original ResearchConceptsPrevention of motherProvider satisfactionPatient satisfactionWeeks postpartumControl armIntervention sitesChild HIV transmission servicesChild HIV transmission rateMother-infant careCD4 cell countHIV transmission ratesCluster-randomized trialTotal patient satisfactionAntiretroviral therapyHIV careChild transmissionPrescribed treatmentClinician satisfactionHealth personnelLower cadre workersCell countHealth problemsMale involvementProvider rolesProviders' ability
2015
High mobile phone ownership, but low Internet and email usage among pregnant, HIV-infected women attending antenatal care in Johannesburg
Clouse K, Schwartz SR, Van Rie A, Bassett J, Vermund SH, Pettifor AE. High mobile phone ownership, but low Internet and email usage among pregnant, HIV-infected women attending antenatal care in Johannesburg. Journal Of Telemedicine And Telecare 2015, 21: 104-107. PMID: 25586808, PMCID: PMC4860457, DOI: 10.1177/1357633x14566569.Peer-Reviewed Original ResearchConceptsHIV-positive pregnant womenMedian timePregnant womenPrevention of motherPrimary care clinicsInternet-based interventionsMobile phone interventionCurrent phone numbersAntenatal careChild transmissionMedian ageAntenatal servicesCare clinicsHigh mobile phone ownershipPhone interventionWomenHIVOne-thirdMobile phone ownershipOne-fifthInterventionYearsMobile phone numbersPhone numberSemi-structured interviews
2014
Integrated prevention of mother-to-child transmission for human immunodeficiency virus, syphilis and hepatitis B virus in China
Wang AL, Qiao YP, Wang LH, Fang LW, Wang F, Jin X, Qiu J, Wang XY, Wang Q, Wu JL, Vermund SH, Song L. Integrated prevention of mother-to-child transmission for human immunodeficiency virus, syphilis and hepatitis B virus in China. Bulletin Of The World Health Organization 2014, 93: 52-56. PMID: 25558108, PMCID: PMC4271682, DOI: 10.2471/blt.14.139626.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusHepatitis B virusAntenatal care clinicsChild transmissionPregnant womenPMTCT servicesCare clinicsImmunodeficiency virusB virusChild transmission effortsRate of maternalChild health clinicsChild health servicesRoutine maternalHBV infectionInfected womenCongenital syphilisHIV programsGeneral HospitalHealth clinicsLive birthsFurther interventionStandardized preventionSyphilis transmissionHealth servicesStrategic Roles for Health Communication in Combination HIV Prevention and Care Programs
Vermund SH, Van Lith LM, Holtgrave D. Strategic Roles for Health Communication in Combination HIV Prevention and Care Programs. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2014, 66: s237-s240. PMID: 25007259, DOI: 10.1097/qai.0000000000000244.Peer-Reviewed Original ResearchConceptsHIV preventionHealth communicationAcquired Immune Deficiency SyndromeVoluntary medical male circumcisionPrevention of motherOpiate substitution therapyImmune deficiency syndromeCombination HIV preventionMedical male circumcisionRisk of HIVHealth communication expertsEvidence of effectivenessHealth communication strategiesEffective health communicationHealth communication approachChild transmissionPreexposure prophylaxisHIV controlSubstitution therapyDeficiency syndromeCurrent evidenceMale circumcisionCare programNeedle exchangePreventionGlobal HIV Epidemiology: A Guide for Strategies in Prevention and Care
Vermund SH. Global HIV Epidemiology: A Guide for Strategies in Prevention and Care. Current HIV/AIDS Reports 2014, 11: 93-98. PMID: 24691698, PMCID: PMC4042676, DOI: 10.1007/s11904-014-0208-x.Peer-Reviewed Original ResearchConceptsRisk populationsFemale sex worker cohortSex worker cohortPrevention of motherOpiate substitution therapyHIV prevention strategiesConsiderable clinical benefitPublic health approachRepresentative population sampleLow infectiousnessAntiretroviral therapyChild transmissionHIV incidenceClinical benefitSubstitution therapyConcentrated epidemicsHIV epidemicSentinel populationYoung MSMPrevalence surveyGeneralized epidemicsIncidence estimatesNeedle useEffective carePrevention services
2013
Optimizing PMTCT service delivery in rural North-Central Nigeria: Protocol and design for a cluster randomized study
Aliyu MH, Blevins M, Audet C, Shepherd BE, Hassan A, Onwujekwe O, Gebi UI, Kalish M, Lindegren ML, Vermund SH, Wester CW. Optimizing PMTCT service delivery in rural North-Central Nigeria: Protocol and design for a cluster randomized study. Contemporary Clinical Trials 2013, 36: 187-197. PMID: 23816493, PMCID: PMC3786261, DOI: 10.1016/j.cct.2013.06.013.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Retroviral AgentsCD4 Lymphocyte CountCost-Benefit AnalysisFamilyFemaleHIV InfectionsHumansInfantInfant, NewbornInfectious Disease Transmission, VerticalMaternal-Child Health CentersMentorsNigeriaPatient SatisfactionPoint-of-Care SystemsPregnancyPrenatal CareResearch DesignRural PopulationSocioeconomic FactorsConceptsAntiretroviral therapyPMTCT servicesChild transmissionHIV service integrationPMTCT service deliveryPMTCT service provisionChild HIV transmissionPrevention of motherCell count testingSimilar resource-limited settingsRural health facilitiesRural North-Central NigeriaResource-limited settingsPatient care responsibilitiesPMTCT careMore HIVHIV infectionCare CD4Cell count resultsHIV transmissionPregnant womenUNAIDS/Health facilitiesHealth providersInfluential community membersTranslation of Biomedical Prevention Strategies for HIV
Vermund SH, Tique JA, Cassell HM, Pask ME, Ciampa PJ, Audet CM. Translation of Biomedical Prevention Strategies for HIV. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2013, 63: s12-s25. PMID: 23673881, PMCID: PMC3725750, DOI: 10.1097/qai.0b013e31829202a2.Peer-Reviewed Original ResearchConceptsPrevention of motherPrevention strategiesClean injection equipmentChild HIV transmissionBiomedical approachBiomedical prevention strategiesRisk of acquisitionHIV prevention strategiesBehavioral risk reductionHigh-prevalence regionsRisk of transmissionCircumcision of menBlood product safetyChild transmissionHIV transmissionAntiretroviral drugsPrevalence regionsHIV preventionHIVFamily planningMore childrenPreventionRisk reductionInjection equipmentSaharan Africa
2012
The HIV Epidemic: High-Income Countries
Vermund SH, Leigh-Brown AJ. The HIV Epidemic: High-Income Countries. Cold Spring Harbor Perspectives In Medicine 2012, 2: a007195. PMID: 22553497, PMCID: PMC3331688, DOI: 10.1101/cshperspect.a007195.Peer-Reviewed Original ResearchConceptsInjection drug useHIV epidemicDrug useNeedle/syringe sharingReceptive anal intercourseDifferent risk groupsRecent explosive epidemicsAntiretroviral therapyChild transmissionSyringe sharingAffected subgroupRisk groupsAnal intercourseVaginal intercourseHIV vulnerabilityExplosive epidemicsDiagnostic screeningEpidemicIncome countriesIntercourseUnited StatesSpecific strainsHigh-income nationsHIVTherapy
2010
A cluster-randomized trial of enhanced labor ward-based PMTCT services to increase nevirapine coverage in Lusaka, Zambia
Megazzini KM, Sinkala M, Vermund SH, Redden DT, Krebs DW, Acosta EP, Mwanza J, Goldenberg RL, Chintu N, Bulterys M, Stringer JS. A cluster-randomized trial of enhanced labor ward-based PMTCT services to increase nevirapine coverage in Lusaka, Zambia. AIDS 2010, 24: 447-455. PMID: 19926959, DOI: 10.1097/qad.0b013e328334b285.Peer-Reviewed Original ResearchConceptsWomen/infant pairsCluster-randomized trialNevirapine coverageInfant pairsLabour wardClinic coverageProbability of HIVProportion of HIVPrevention of motherStandard of carePMTCT programmePMTCT servicesChild transmissionHIV testingUnknown serostatusSurveillance periodIntervention periodControl clinicsRelative riskTreatment clinicsUmbilical cordHIVClinicGEE modelOdds of coverage
2009
Selected hematologic and biochemical measurements in African HIV-infected and uninfected pregnant women and their infants: the HIV Prevention Trials Network 024 protocol
Mwinga K, Vermund SH, Chen YQ, Mwatha A, Read JS, Urassa W, Carpenetti N, Valentine M, Goldenberg RL. Selected hematologic and biochemical measurements in African HIV-infected and uninfected pregnant women and their infants: the HIV Prevention Trials Network 024 protocol. BMC Pediatrics 2009, 9: 49. PMID: 19664210, PMCID: PMC2746190, DOI: 10.1186/1471-2431-9-49.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-HIV AgentsBlood Cell CountDouble-Blind MethodFemaleFollow-Up StudiesGestational AgeHematocritHemoglobinsHIVHIV InfectionsHumansIncidenceInfantInfant, NewbornMalawiNevirapinePregnancyPregnancy Complications, InfectiousRetrospective StudiesRNA, ViralTanzaniaTreatment OutcomeYoung AdultZambiaConceptsHIV infectionPregnant African womenRandomized clinical trialsTime of laborComplete laboratory dataWeeks of ageNevirapine prophylaxisChild transmissionHIV exposureWeeks' gestationHIV statusPregnant womenNewborn infantsClinical trialsPublic clinicsHIVInfantsBiochemical measurementsCaucasian populationWomenLaboratory dataNormative dataAfrican womenInfectionWeeks
2007
Influence of body mass index on pregnancy outcomes among HIV‐infected and HIV‐uninfected Zambian women
Banda Y, Chapman V, Goldenberg RL, H. B, Vermund SH, Stringer JS. Influence of body mass index on pregnancy outcomes among HIV‐infected and HIV‐uninfected Zambian women. Tropical Medicine And International Health 2007, 12: 856-861. PMID: 17596253, PMCID: PMC2570322, DOI: 10.1111/j.1365-3156.2007.01857.x.Peer-Reviewed Original ResearchConceptsBody mass indexPregnancy outcomesBirth weightInfant weightMass indexZambian womenBMI unitsLower body mass indexChild transmission ratePerinatal HIV transmissionPrevention of motherHIV viral loadInfant birth weightMean birth weightTransmission of HIVNevirapine administrationPrior stillbirthBMI quartilesCD4 countChild transmissionViral loadHIV transmissionMaternal parityUnivariate analysisClinical trialsMonitoring and evaluation of programmes to prevent mother to child transmission of HIV in Africa
Reithinger R, Megazzini K, Durako SJ, Harris DR, Vermund SH. Monitoring and evaluation of programmes to prevent mother to child transmission of HIV in Africa. The BMJ 2007, 334: 1143. PMID: 17540943, PMCID: PMC1885318, DOI: 10.1136/bmj.39211.527488.94.Peer-Reviewed Original Research
2006
Use of Vaginally Administered Chlorhexidine During Labor to Improve Pregnancy Outcomes
Goldenberg RL, McClure EM, Saleem S, Rouse D, Vermund S. Use of Vaginally Administered Chlorhexidine During Labor to Improve Pregnancy Outcomes. Obstetrics And Gynecology 2006, 107: 1139-1146. PMID: 16648420, DOI: 10.1097/01.aog.0000215000.65665.dd.Peer-Reviewed Original ResearchConceptsPregnancy outcomesHuman immunodeficiency virusExcellent safety profileGroup B streptococciUse of chlorhexidineChild transmissionNeonatal sepsisNeonatal infectionChlorhexidine useVaginal treatmentImmunodeficiency virusNeonatal mortalityPregnant womenSafety profileAdverse outcomesNewborn periodSTUDY SELECTIONB streptococciPromising treatmentChlorhexidine treatmentBacterial loadChlorhexidineEffective killersEnglish literatureFurther studies
2004
Universal nevirapine upon presentation in labor to prevent mother-to-child HIV transmission in high prevalence settings
Stringer J, Sinkala M, Goldenberg RL, Kumwenda R, Acosta EP, Aldrovandi GM, Stout JP, Vermund SH. Universal nevirapine upon presentation in labor to prevent mother-to-child HIV transmission in high prevalence settings. AIDS 2004, 18: 939-943. PMID: 15060442, PMCID: PMC2745979, DOI: 10.1097/00002030-200404090-00012.Peer-Reviewed Original ResearchConceptsChild HIV transmissionUnknown HIV serostatusHIV serostatusHIV transmissionPreliminary efficacyLabour wardHIV DNA polymerase chain reactionSingle-dose nevirapinePrevention of motherProspective cohort studyEvidence of infectionHigh-prevalence settingsWeeks of lifeNevirapine administrationNevirapine coverageChild transmissionCohort studyComparison cohortAdherence ratesPrevalence settingsPolymerase chain reactionCord bloodDNA polymerase chain reactionHIVInfant specimensTolerance and Safety of Different Concentrations of Chlorhexidine for Peripartum Vaginal and Infant Washes: HIVNET 025
Wilson CM, Gray G, Read JS, Mwatha A, Lala S, Johnson S, Violari A, Sibiya PM, Fleming TR, Koonce A, Vermund SH, McIntyre J. Tolerance and Safety of Different Concentrations of Chlorhexidine for Peripartum Vaginal and Infant Washes: HIVNET 025. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2004, 35: 138-143. PMID: 14722445, PMCID: PMC2753236, DOI: 10.1097/00126334-200402010-00006.Peer-Reviewed Original ResearchConceptsChris Hani Baragwanath HospitalPrevention of motherHIV Type 1Solution of chlorhexidineConcentrations of chlorhexidineChild transmissionBaragwanath HospitalMaternal symptomsPrevention trialsThird trimesterClinical indicationsMaternity unitsSubjective complaintsVaginal areaWash groupType 1ChlorhexidineInfant examinationWomenSustainable interventionsTolerable concentrationInterventionMothersWashDifferent concentrationsPrevention of mother-to-child transmission of HIV in Africa.
Vermund SH. Prevention of mother-to-child transmission of HIV in Africa. Topics In Antiviral Medicine 2004, 12: 130-4. PMID: 15647608.Peer-Reviewed Original ResearchConceptsChild transmissionHIV infectionInternational AIDS Society-USA courseMaternal plasma viral loadExclusive formula feedingNevirapine resistance mutationsSingle-dose nevirapinePrevention of motherPlasma viral loadPerinatal transmission ratePerinatal transmissionAntiretroviral therapyExclusive breastfeedingFormula feedingViral loadMaternal mortalityRisk factorsMortality rateHIVAfrican childrenMixed feedingGreater riskResistance mutationsEarly weaningBreastfeeding
2003
Prevention of mother-to-child transmission of HIV in Africa: successes and challenges in scaling-up a nevirapine-based program in Lusaka, Zambia
Stringer EM, Sinkala M, Stringer J, Mzyece E, Makuka I, Goldenberg RL, Kwape P, Chilufya M, Vermund SH. Prevention of mother-to-child transmission of HIV in Africa: successes and challenges in scaling-up a nevirapine-based program in Lusaka, Zambia. AIDS 2003, 17: 1377-1382. PMID: 12799559, PMCID: PMC2745990, DOI: 10.1097/00002030-200306130-00012.Peer-Reviewed Original ResearchConceptsPrevention of motherResource-limited settingsHIV infectionVoluntary counselingChild HIV transmissionPerinatal HIV infectionHIV prevention programsNVP therapyChild transmissionPatient attritionHIV transmissionPregnant womenPrevention programsNevirapineHIVHealth employeesThousands of womenTransmission routesLusakaMothersInfectionPreventionWomenCounselingInfants
1999
Prevention of mother-to-child transmission of HIV-1
Stringer J, Vermund S. Prevention of mother-to-child transmission of HIV-1. Current Opinion In Obstetrics & Gynecology 1999, 11: 427-434. PMID: 10526917, DOI: 10.1097/00001703-199910000-00003.Peer-Reviewed Original ResearchConceptsChild transmissionHIV-1Infant formula supplementationPrevention of motherHIV-1 transmissionCombination drug regimensResource-poor settingsFormula supplementationAntiretroviral therapyCesarean deliveryAntiretroviral agentsBreast feedingDrug regimensRandomized trialsPoor settingsInfectious diseasesInfant survivalSubstantial proportionPreliminary dataMothersLower ratesCost implicationsDeliveryRegimensPatients