2022
“If it weren’t for my traditional healer, I would be dead”: Engaging traditional healers to support people living with HIV in rural Mozambique
Audet CM, Pettapiece-Phillips M, Tian Y, Shepherd BE, Vermund SH, Salato J. “If it weren’t for my traditional healer, I would be dead”: Engaging traditional healers to support people living with HIV in rural Mozambique. PLOS ONE 2022, 17: e0270565. PMID: 35763519, PMCID: PMC9239464, DOI: 10.1371/journal.pone.0270565.Peer-Reviewed Original ResearchConceptsTraditional healersPsychosocial supportCommunity health worker interventionPre-post intervention study designWorker interventionHealth worker interventionMedication possession ratioMedication side effectsIntervention study designPositive test resultsHome-based supportObserved therapyPossession ratioClinical outcomesHIV treatmentPoor adherencePost-intervention participantsHealth facilitiesPatient's desireSide effectsZambézia ProvinceCare servicesStudy designHIVTherapy
2021
Syndemic Framework Evaluation of Severe COVID-19 Outcomes in the United States: Factors Associated With Race and Ethnicity
Williams C, Vermund SH. Syndemic Framework Evaluation of Severe COVID-19 Outcomes in the United States: Factors Associated With Race and Ethnicity. Frontiers In Public Health 2021, 9: 720264. PMID: 34616705, PMCID: PMC8488144, DOI: 10.3389/fpubh.2021.720264.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 infection riskSevere COVID-19 outcomesSevere clinical outcomesCOVID-19 outcomesSeverity of diseaseAssociated disease burdenCOVID-19Ethnic health inequalitiesIndividual clinical dataClinical care environmentLong-term careCoronavirus disease (COVID-19) pandemicClinical outcomesSyndemic factorsDisease burdenClinical dataHealthcare barriersHealth outcomesInfection riskHealth inequalitiesDisease pandemicSyndemic theoryVulnerable populationsCare environmentFuture pandemics
2014
Poor Clinical Outcomes for HIV Infected Children on Antiretroviral Therapy in Rural Mozambique: Need for Program Quality Improvement and Community Engagement
Vermund SH, Blevins M, Moon TD, José E, Moiane L, Tique JA, Sidat M, Ciampa PJ, Shepherd BE, Vaz LM. Poor Clinical Outcomes for HIV Infected Children on Antiretroviral Therapy in Rural Mozambique: Need for Program Quality Improvement and Community Engagement. PLOS ONE 2014, 9: e110116. PMID: 25330113, PMCID: PMC4203761, DOI: 10.1371/journal.pone.0110116.Peer-Reviewed Original ResearchConceptsCombination antiretroviral therapyAntiretroviral therapyInfant diagnosisClinical outcomesEarly infant diagnosisPoor clinical outcomeYears of ageResource-limited settingsUnknown clinical outcomesCohort mortality ratesQuality improvement effortsART initiationCART initiationRural MozambiqueHIV servicesAdults 15HIV prevalenceKaplan-MeierHigher hemoglobinMedication pickupClinical dataOutcome treatmentNational guidelinesCase findingZambézia Province
2013
Educational Intervention Increased Referrals to Allopathic Care by Traditional Healers in Three High HIV-Prevalence Rural Districts in Mozambique
Audet CM, Salato J, Blevins M, Amsalem D, Vermund SH, Gaspar F. Educational Intervention Increased Referrals to Allopathic Care by Traditional Healers in Three High HIV-Prevalence Rural Districts in Mozambique. PLOS ONE 2013, 8: e70326. PMID: 23936407, PMCID: PMC3731350, DOI: 10.1371/journal.pone.0070326.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusReferral ratesTraditional healersHealth facilitiesNon-pregnant personsFavorable clinical outcomeHIV knowledge scoresPost-intervention ratesMonthly referral rateRural districtsClinical outcomesImmunodeficiency virusPregnant womenHIV knowledgeZambézia ProvincePatientsKnowledge scoreInexpensive interventionClinical servicesHealth systemMedian scoreEducational interventionTuberculosisCareClinic
2012
Availability of Volunteer-Led Home-Based Care System and Baseline Factors as Predictors of Clinical Outcomes in HIV-Infected Patients in Rural Zambia
Estopinal CB, van Dijk JH, Sitali S, Stewart H, Davidson MA, Spurrier J, Vermund SH. Availability of Volunteer-Led Home-Based Care System and Baseline Factors as Predictors of Clinical Outcomes in HIV-Infected Patients in Rural Zambia. PLOS ONE 2012, 7: e49564. PMID: 23236351, PMCID: PMC3517597, DOI: 10.1371/journal.pone.0049564.Peer-Reviewed Original ResearchConceptsBody mass indexHome-based careLower body mass indexART initiationAntiretroviral therapyUnfavorable outcomeTreatment outcomesFavorable outcomeRural Southern ProvinceCell countRetrospective cohort studyImproved treatment outcomesEligible patientsHBC programmesLow CD4HIV careAdherence counselingCohort studyDate of birthBaseline factorsMedical chartsBivariable analysisClinical outcomesMass indexMultivariable analysis
2010
Implementation of cervical cancer prevention services for HIV-infected women in Zambia: measuring program effectiveness
Parham GP, Mwanahamuntu MH, Sahasrabuddhe VV, Westfall AO, King KE, Chibwesha C, Pfaendler KS, Mkumba G, Mudenda V, Kapambwe S, Vermund SH, Hicks ML, Stringer JS, Chi BH. Implementation of cervical cancer prevention services for HIV-infected women in Zambia: measuring program effectiveness. HIV Therapy 2010, 4: 713-722. PMID: 25419240, PMCID: PMC4237284, DOI: 10.2217/hiv.10.52.Peer-Reviewed Original ResearchCervical cancer deathsCervical cancer prevention programsCancer prevention programsCervical cancerCancer deathHistologic evaluationHIV/AIDS care programsVisible lesionsCervical cancer prevention methodsCervical cancer prevention servicesPrevention programsCervical intraepithelial neoplasia (CIN) IPrevention effortsCancer prevention servicesCancer prevention methodsIntraepithelial neoplasia IAIDS care programsFuture prevention effortsCIN 2/3Clinical outcomesClinical managementProgram effectivenessPrevention servicesHIVCare program
2008
Predictors of Adherence to Antiretroviral Therapy in Rural Zambia
Carlucci JG, Kamanga A, Sheneberger R, Shepherd BE, Jenkins CA, Spurrier J, Vermund SH. Predictors of Adherence to Antiretroviral Therapy in Rural Zambia. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2008, 47: 615-622. PMID: 18209678, PMCID: PMC2743102, DOI: 10.1097/qai.0b013e318165dc25.Peer-Reviewed Original ResearchConceptsRural health facilitiesHIV/AIDS careRural ZambiaBetter clinical outcomesBody mass indexHIV drug resistancePredictors of adherenceResource-limited settingsAntiretroviral therapyAIDS stagePatient demographicsPill countPharmacy recordsClinical outcomesMass indexAdherence ratesClinical indicesAIDS careAdherence levelsHealth facilitiesOptimize outcomesPatient's homeMission hospitalPatientsStudy participants
1993
Trends in the Incidence of Outcomes Defining Acquired Immunodeficiency Syndrome (AIDS) in the Multicenter AIDS Cohort Study: 1985–1991
Muñoz A, Schrager L, Bacellar H, Speizer I, Vermund S, Detels R, Saah A, Kingsley L, Seminara D, Phair J. Trends in the Incidence of Outcomes Defining Acquired Immunodeficiency Syndrome (AIDS) in the Multicenter AIDS Cohort Study: 1985–1991. American Journal Of Epidemiology 1993, 137: 423-438. PMID: 8096356, DOI: 10.1093/oxfordjournals.aje.a116691.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeAIDS-Related Opportunistic InfectionsCD4-Positive T-LymphocytesCohort StudiesCytomegalovirus InfectionsHerpes SimplexHIV SeropositivityHIV-1HumansIncidenceLeukocyte CountLymphomaMaleNervous System DiseasesPneumonia, PneumocystisProspective StudiesRegression AnalysisRisk FactorsSarcoma, KaposiUnited StatesConceptsAcquired Immunodeficiency SyndromeP. carinii pneumoniaCarinii pneumoniaProgressive immunosuppressionKaposi's sarcomaImmunodeficiency syndromeOpportunistic infectionsHerpes simplex virus infectionHuman immunodeficiency virus type 1Multicenter AIDS Cohort StudyImmunodeficiency virus type 1Use of chemoprophylaxisUse of prophylaxisIncidence of outcomesPneumocystis carinii pneumoniaSimplex virus infectionAIDS Cohort StudyVirus type 1Antiretroviral therapyCohort studyClinical outcomesInitial diagnosisSecondary diagnosisLower incidenceNeurologic disease
1992
Human immunodeficiency virus/acquired immunodeficiency syndrome in pregnant women
Vermund S, Galbraith M, Ebner S, Sheon A, Kaslow R. Human immunodeficiency virus/acquired immunodeficiency syndrome in pregnant women. Annals Of Epidemiology 1992, 2: 773-802. PMID: 1342332, DOI: 10.1016/1047-2797(92)90072-x.Peer-Reviewed Original ResearchConceptsPregnant womenClinical outcomesHuman immunodeficiency virus/Anti-Pneumocystis drugsCells/mm3Adverse clinical outcomesHigh-risk womenHuman immunodeficiency virusLarge multicenter studyImmunodeficiency syndrome (AIDS) epidemicAdequate clinical treatmentHealth care servicesClinical decision makingPerinatal transmissionSelective immunosuppressionHIV diseaseImmunosuppressed womenAvailable antiviralsHIV infectionImmunodeficiency syndromeImmunodeficiency virusMulticenter studyVirus/Therapeutic decisionsHigh risk
1990
How can epidemiology assist in guiding interventions for the acquired immunodeficiency syndrome/human immunodeficiency virus?
Vermund S, Hoth D. How can epidemiology assist in guiding interventions for the acquired immunodeficiency syndrome/human immunodeficiency virus? Annals Of Epidemiology 1990, 1: 141-155. PMID: 1669495, DOI: 10.1016/1047-2797(90)90005-d.Peer-Reviewed Original ResearchConceptsNew therapiesHIV infectionTherapeutic trialsClinical trialsImmunodeficiency syndrome/human immunodeficiency virusVaccine developmentHuman immunodeficiency virus (HIV) infectionRecent drug trialsImmunodeficiency virus infectionDevelopment of AIDSHost immunologic responseHuman immunodeficiency virusSuch clinical parametersFuture epidemiologic researchClinical therapeutic researchNatural history studiesUse of condomsEffect of treatmentClinical research methodsVariety of treatmentsAIDS/HIV epidemicClinical courseClinical outcomesClinical parametersImmunodeficiency virus