2016
Integrated prevention of mother-to-child HIV transmission services, antiretroviral therapy initiation, and maternal and infant retention in care in rural north-central Nigeria: a cluster-randomised controlled trial
Aliyu MH, Blevins M, Audet CM, Kalish M, Gebi UI, Onwujekwe O, Lindegren ML, Shepherd BE, Wester CW, Vermund SH. Integrated prevention of mother-to-child HIV transmission services, antiretroviral therapy initiation, and maternal and infant retention in care in rural north-central Nigeria: a cluster-randomised controlled trial. The Lancet HIV 2016, 3: e202-e211. PMID: 27126487, PMCID: PMC4852280, DOI: 10.1016/s2352-3018(16)00018-7.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeAdolescentAdultAnti-HIV AgentsCD4 Lymphocyte CountDelivery of Health Care, IntegratedEarly Intervention, EducationalFamilyFemaleHIV InfectionsHumansInfantInfectious Disease Transmission, VerticalMaleMothersNevirapineNigeriaPregnancyPregnancy Complications, InfectiousPrenatal CareRural PopulationYoung AdultConceptsChild HIV transmissionAntiretroviral therapyStandard of careRural North-Central NigeriaWeeks post partumIntervention groupAntiretroviral prophylaxisEligible womenHIV statusHIV transmissionSecondary level health care facilitiesChild HIV transmission servicesClinical stage 1 diseasePost partumEunice Kennedy Shriver National InstituteMedian CD4 countPMTCT service deliveryAntiretroviral therapy initiationCD4 cell countPrevention of motherStage 1 diseaseUnknown HIV statusElimination of motherNorth Central NigeriaEarly infant diagnosis
2014
Poor Clinical Outcomes for HIV Infected Children on Antiretroviral Therapy in Rural Mozambique: Need for Program Quality Improvement and Community Engagement
Vermund SH, Blevins M, Moon TD, José E, Moiane L, Tique JA, Sidat M, Ciampa PJ, Shepherd BE, Vaz LM. Poor Clinical Outcomes for HIV Infected Children on Antiretroviral Therapy in Rural Mozambique: Need for Program Quality Improvement and Community Engagement. PLOS ONE 2014, 9: e110116. PMID: 25330113, PMCID: PMC4203761, DOI: 10.1371/journal.pone.0110116.Peer-Reviewed Original ResearchConceptsCombination antiretroviral therapyAntiretroviral therapyInfant diagnosisClinical outcomesEarly infant diagnosisPoor clinical outcomeYears of ageResource-limited settingsUnknown clinical outcomesCohort mortality ratesQuality improvement effortsART initiationCART initiationRural MozambiqueHIV servicesAdults 15HIV prevalenceKaplan-MeierHigher hemoglobinMedication pickupClinical dataOutcome treatmentNational guidelinesCase findingZambézia ProvinceCorrelates of Suboptimal Entry Into Early Infant Diagnosis in Rural North Central Nigeria
Aliyu MH, Blevins M, Megazzini KM, Audet CM, Dunlap J, Sodangi IS, Gebi UI, Shepherd BE, Wester CW, Vermund SH. Correlates of Suboptimal Entry Into Early Infant Diagnosis in Rural North Central Nigeria. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2014, 67: e19-e26. PMID: 24853310, PMCID: PMC4134378, DOI: 10.1097/qai.0000000000000215.Peer-Reviewed Original ResearchConceptsEarly infant diagnosisRural North-Central NigeriaInfant diagnosisPregnant womenChild HIV transmission (PMTCT) programsHIV care/treatmentClinic of enrolmentPediatric HIV infectionPrevention of motherNorth Central NigeriaMultivariable logistic regressionCare/treatmentDate of enrollmentHIV service uptakeEID uptakeCohort studyHIV infectionLaboratory variablesClinic locationService uptakeMaternal factorsTransmission programInfantsReferral sourceLogistic regression
2012
Addressing Poor Retention of Infants Exposed to HIV
Ciampa PJ, Tique JA, Jumá N, Sidat M, Moon TD, Rothman RL, Vermund SH. Addressing Poor Retention of Infants Exposed to HIV. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2012, 60: e46-e52. PMID: 22622077, PMCID: PMC3587032, DOI: 10.1097/qai.0b013e31824c0267.Peer-Reviewed Original ResearchConceptsEarly infant diagnosisMother/infant pairsInfant pairsEnhanced referralProportion of HIVDays of lifePhase 2 groupProcess of referralLow-resource countriesPhase 2Phase 1Quality improvement effortsHIV carePostpartum dischargeInfant diagnosisAdjusted analysisCox regressionKaplan-MeierDistrict hospitalMedical recordsMAIN OUTCOMEQuality improvement methodsHIVInfantsReferral
2011
Improving Retention in the Early Infant Diagnosis of HIV Program in Rural Mozambique by Better Service Integration
Ciampa PJ, Burlison JR, Blevins M, Sidat M, Moon TD, Rothman RL, Vermund SH. Improving Retention in the Early Infant Diagnosis of HIV Program in Rural Mozambique by Better Service Integration. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2011, 58: 115-119. PMID: 21546845, DOI: 10.1097/qai.0b013e31822149bf.Peer-Reviewed Original ResearchConceptsEarly infant diagnosisInfant diagnosisInfant testingEarly infant testingWomen/infantsRetrospective record reviewPostpartum HIVRural MozambiqueRecord reviewStandard referralHIV programsHigher oddsReferral processSimple interventionHIVReferralDiagnosisInfant retentionWomenService integrationInfantsPredictors of Successful Early Infant Diagnosis of HIV in a Rural District Hospital in Zambézia, Mozambique
Cook RE, Ciampa PJ, Sidat M, Blevins M, Burlison J, Davidson MA, Arroz JA, Vergara AE, Vermund SH, Moon TD. Predictors of Successful Early Infant Diagnosis of HIV in a Rural District Hospital in Zambézia, Mozambique. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2011, 56: e104-e109. PMID: 21266912, PMCID: PMC3073723, DOI: 10.1097/qai.0b013e318207a535.Peer-Reviewed Original ResearchConceptsEarly infant diagnosisInfant diagnosisHIV diagnosisMaternal receiptAntiretroviral therapyEarly infant HIV diagnosisMultivariable logistic regression modelHIV-infected mothersLinkage of HIVRural Zambézia ProvinceHIV care clinicsInfant HIV diagnosisRural district hospitalMother-infant pairsPaediatric antiretroviral treatmentLocal health authoritiesLogistic regression modelsRetrospective cohortAntiretroviral treatmentMedian ageCare clinicsMaternal healthDistrict hospitalTimely initiationHIV