2004
Prevention of mother-to-child transmission of HIV in Africa.
Vermund SH. Prevention of mother-to-child transmission of HIV in Africa. Topics In Antiviral Medicine 2004, 12: 130-4. PMID: 15647608.Peer-Reviewed Original ResearchConceptsChild transmissionHIV infectionInternational AIDS Society-USA courseMaternal plasma viral loadExclusive formula feedingNevirapine resistance mutationsSingle-dose nevirapinePrevention of motherPlasma viral loadPerinatal transmission ratePerinatal transmissionAntiretroviral therapyExclusive breastfeedingFormula feedingViral loadMaternal mortalityRisk factorsMortality rateHIVAfrican childrenMixed feedingGreater riskResistance mutationsEarly weaningBreastfeeding
2003
Timing of the maternal drug dose and risk of perinatal HIV transmission in the setting of intrapartum and neonatal single-dose nevirapine
Stringer J, Sinkala M, Chapman V, Acosta EP, Aldrovandi GM, Mudenda V, Stout JP, Goldenberg RL, Kumwenda R, Vermund SH. Timing of the maternal drug dose and risk of perinatal HIV transmission in the setting of intrapartum and neonatal single-dose nevirapine. AIDS 2003, 17: 1659-1665. PMID: 12853748, PMCID: PMC2745973, DOI: 10.1097/00002030-200307250-00010.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBreast FeedingDrug Administration ScheduleFemaleHIV InfectionsHIV SeropositivityHumansInfant, NewbornInfectious Disease Transmission, VerticalLabor, ObstetricNevirapineObstetric Labor ComplicationsPregnancyPregnancy Complications, InfectiousProspective StudiesReverse Transcriptase InhibitorsRisk FactorsTime FactorsConceptsPerinatal HIV transmissionHIV transmissionInfant HIV infection statusNeonatal single-dose nevirapineMaternal drug doseSingle-dose nevirapineHIV infection statusProspective cohort studyPerinatal transmission rateOnset of laborMain outcome measuresMean drug concentrationWeeks of lifeRisk of transmissionNVP levelsNVP prophylaxisNVP syrupObstetrical clinicPerinatal transmissionCohort studyOral doseViral loadPregnant womenPolymerase chain reactionRisk factors