2022
Projected outcomes of universal testing and treatment in a generalised HIV epidemic in Zambia and South Africa (the HPTN 071 [PopART] trial): a modelling study
Probert W, Sauter R, Pickles M, Cori A, Bell-Mandla N, Bwalya J, Abeler-Dörner L, Bock P, Donnell D, Floyd S, Macleod D, Piwowar-Manning E, Skalland T, Shanaube K, Wilson E, Yang B, Ayles H, Fidler S, Hayes R, Fraser C, Team H, Hayes R, Fidler S, Beyers N, Ayles H, Bock P, El-Sadr W, Cohen M, Eshleman S, Agyei Y, Piwowar-Manning E, Bond V, Hoddinott G, Donnell D, Floyd S, Wilson E, Emel L, Noble H, Macleod D, Burns D, Fraser C, Cori A, Sista N, Griffith S, Moore A, Headen T, White R, Miller E, Hargreaves J, Hauck K, Thomas R, Limbada M, Bwalya J, Pickles M, Sabapathy K, Schaap, Dunbar R, Shanaube K, Yang B, Simwinga M, Smith P, Vermund S, Mandla N, Makola N, van Deventer A, James A, Jennings K, Kruger J, Phiri M, Kosloff B, Mwenge L, Kanema S, Sauter R, Probert W, Kumar R, Sakala E, Silumesi A, Skalland T, Yuhas K. Projected outcomes of universal testing and treatment in a generalised HIV epidemic in Zambia and South Africa (the HPTN 071 [PopART] trial): a modelling study. The Lancet HIV 2022, 9: e771-e780. PMID: 36332654, PMCID: PMC9646978, DOI: 10.1016/s2352-3018(22)00259-4.Peer-Reviewed Original ResearchConceptsStandard of careHome-based testingCluster-randomised trialHigh-prevalence communitiesHIV incidenceHIV epidemicNational guidelinesNational InstituteUniversal testingHIV care cascadeAntiretroviral therapy uptakeUS President's Emergency PlanGeneralised HIV epidemicPresident's Emergency PlanPopART interventionCare cascadeART eligibilityArm BTherapy uptakeTrial interventionTrial dataInfectious diseasesAIDS ReliefIntervention impactDrug abuse
2020
Monitoring Pharmacy and Test Kit Stocks in Rural Mozambique: U.S. President's Emergency Plan for AIDS Relief Surveillance to Help Prevent Ministry of Health Shortages
Bravo M, Peratikos MB, Muicha AS, Mahagaja E, Alvim MFS, Green AF, Wester CW, Vermund SH. Monitoring Pharmacy and Test Kit Stocks in Rural Mozambique: U.S. President's Emergency Plan for AIDS Relief Surveillance to Help Prevent Ministry of Health Shortages. AIDS Research And Human Retroviruses 2020, 36: 415-426. PMID: 31914787, PMCID: PMC7232670, DOI: 10.1089/aid.2019.0057.Peer-Reviewed Original ResearchConceptsRural Zambézia ProvinceHuman immunodeficiency virusPresident's Emergency PlanMedication supplyU.S. President's Emergency PlanTimes higher oddsMedication classesViral suppressionDiagnostic test kitsImmunodeficiency virusPharmacy dataStudy midpointOrdinal logistic regressionHigher oddsCare providersLower oddsZambézia ProvinceTuberculosis testingMonitoring of drugsLogistic regressionAIDS ReliefHealth shortagesARVEmergency plansCalendar time
2017
Differences in health-related quality of life between HIV-positive and HIV-negative people in Zambia and South Africa: a cross-sectional baseline survey of the HPTN 071 (PopART) trial
Thomas R, Burger R, Harper A, Kanema S, Mwenge L, Vanqa N, Bell-Mandla N, Smith P, Floyd S, Bock P, Ayles H, Beyers N, Donnell D, Fidler S, Hayes R, Hauck K, Team H, Hargreaves J, Watson-Jones D, Godfrey-Faussett P, Cori A, Pickles M, Mandla N, Yang B, James A, Vermaak R, Makola N, Hoddinott G, Naidoo V, Bond V, Simwinga M, Mwinga A, Kosloff B, Limbada M, Bwalya J, Ngulube C, Fraser C, Eshleman S, Agyei Y, Cummings V, Catalano D, Emel L, Bunts L, Noble H, Burns D, Kouda A, Sista N, Moore A, White R, Headen T, Miller E, Hinson K, Vermund S, Barnes M, Horn L, Mwango A, Baldwin M, Wolf S, Hughes E. Differences in health-related quality of life between HIV-positive and HIV-negative people in Zambia and South Africa: a cross-sectional baseline survey of the HPTN 071 (PopART) trial. The Lancet Global Health 2017, 5: e1133-e1141. PMID: 28964756, PMCID: PMC5640509, DOI: 10.1016/s2214-109x(17)30367-4.Peer-Reviewed Original ResearchConceptsHIV-negative peopleHIV-positive individualsHIV-negative individualsAntiretroviral therapyHealth-related qualityHIV careHRQoL scoresHIV statusHerpes simplex virus type-2 statusNational InstituteHPTN 071 (PopART) studyHPTN 071 (PopART) trialLaboratory-confirmed HIVType 2 statusCross-sectional baseline surveyLarge cross-sectional surveyRecreational drug useCross-sectional surveyPresident's Emergency PlanGeneral population sampleHRQoL informationBetter HRQoLHIV-negativeHIV progressionHRQoL data
2014
Challenges in the Detection, Prevention, and Treatment of HIV-Associated Malignancies in Low- and Middle-Income Countries in Africa
Adebamowo CA, Casper C, Bhatia K, Mbulaiteye SM, Sasco AJ, Phipps W, Vermund SH, Krown SE. Challenges in the Detection, Prevention, and Treatment of HIV-Associated Malignancies in Low- and Middle-Income Countries in Africa. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2014, 67: s17-s26. PMID: 25117957, PMCID: PMC4392880, DOI: 10.1097/qai.0000000000000255.Peer-Reviewed Original ResearchConceptsMiddle-income countriesAntiretroviral therapy usageChronic HIV careHIV-Associated MalignanciesCombination antiretroviral therapyHIV/AIDSPresident's Emergency PlanLong-term careHealth care infrastructureHIV workforceAntiretroviral therapyHIV careMajor complicationsHIV statusTherapy usageCancer CenterCancer patientsHost genetic profileHigh-income countriesEarly diagnosisBiology of cancerHIVOptimal managementAIDS ReliefCancerMobile clinics for antiretroviral therapy in rural Mozambique
Moon TD, Jequicene T, Blevins M, José E, Lankford JR, Wester CW, Fuchs MC, Vermund SH. Mobile clinics for antiretroviral therapy in rural Mozambique. Bulletin Of The World Health Organization 2014, 92: 680-684. PMID: 25378759, PMCID: PMC4208568, DOI: 10.2471/blt.13.129478.Peer-Reviewed Original ResearchConceptsHIV careClinic strategyHealth care infrastructureAntiretroviral therapy programsHuman immunodeficiency virusUptake of servicesPresident's Emergency PlanLocal health systemsMonths of implementationAntiretroviral therapyImmunodeficiency virusPeripheral clinicsNew patientsMobile clinicsAdult populationART expansionClinicTherapy programAIDS ReliefHealth systemCareTreatmentRural MozambiqueRural regionsNational coverage
2012
Transitioning HIV care and treatment programs in southern Africa to full local management
Vermund SH, Sidat M, Weil LF, Tique JA, Moon TD, Ciampa PJ. Transitioning HIV care and treatment programs in southern Africa to full local management. AIDS 2012, 26: 1303-1310. PMID: 22706012, PMCID: PMC3576840, DOI: 10.1097/qad.0b013e3283552185.Peer-Reviewed Original ResearchConceptsHIV careHIV/AIDS care programsAIDS ProgramPrimary health care systemUS President's Emergency PlanHealth care workersAIDS care programsHealth worker capacityHIV/AIDS programsPresident's Emergency PlanHealth care systemHIV programsAIDS careCare managementCare workersCare programTreatment programAIDS ReliefHealth care managementCare systemCarePrevention endeavorsEmergency plans
2011
Enrolment and programmatic trends and predictors of antiretroviral therapy initiation from President's Emergency Plan for AIDS Relief (PEPFAR)-supported public HIV care and treatment sites in rural Mozambique
Moon TD, Burlison JR, Blevins M, Shepherd BE, Baptista A, Sidat M, Vergara AE, Vermund SH. Enrolment and programmatic trends and predictors of antiretroviral therapy initiation from President's Emergency Plan for AIDS Relief (PEPFAR)-supported public HIV care and treatment sites in rural Mozambique. International Journal Of STD & AIDS 2011, 22: 621-627. PMID: 22096045, DOI: 10.1258/ijsa.2011.010442.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyART initiationAntiretroviral therapy initiationHIV treatment programsCells/μLContinuous drug supplyPresident's Emergency PlanHIV careTherapy initiationHIV testingMedian ageSaharan AfricaTreatment expansionZambézia ProvinceRoutine dataPatient record systemPatientsTreatment programOlder ageAIDS ReliefHealth manpowerCells/Drug supplyRecord systemTreatment sites
2010
Lessons learned while implementing an HIV/AIDS care and treatment program in rural Mozambique.
Moon TD, Burlison JR, Sidat M, Pires P, Silva W, Solis M, Rocha M, Arregui C, Manders EJ, Vergara AE, Vermund SH. Lessons learned while implementing an HIV/AIDS care and treatment program in rural Mozambique. Retrovirology Research And Treatment 2010, 3: 1-14. PMID: 25097450, PMCID: PMC4119752, DOI: 10.4137/rrt.s4613.Peer-Reviewed Original Research