2021
Human Immunodeficiency Virus Infection and Incident Heart Failure: A Meta-Analysis of Prospective Studies
Chen Y, Gao Y, Zhou Y, Li X, Wang H, Polonsky TS, Vermund SH, Qian HZ, Qian F. Human Immunodeficiency Virus Infection and Incident Heart Failure: A Meta-Analysis of Prospective Studies. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2021, 87: 741-749. PMID: 33492019, PMCID: PMC10768809, DOI: 10.1097/qai.0000000000002629.Peer-Reviewed Original ResearchConceptsIncident heart failureLow CD4 countHeart failureHIV infectionRandom-effects modelCD4 countSubgroup analysisRisk of HFHuman immunodeficiency virus (HIV) infectionLaird random-effects modelYoung adultsAvailable prospective evidenceImmunodeficiency virus infectionPooled relative riskFull-text assessmentWeb of ScienceFixed-effects modelProspective studyIncident casesProspective evidenceRelative riskVirus infectionFunnel plotMeta-AnalysisSimilar association
2017
Effects of depression and anxiety on antiretroviral therapy adherence among newly diagnosed HIV-infected Chinese MSM
Tao J, Qian HZ, Kipp AM, Ruan Y, Shepherd BE, Amico KR, Shao Y, Lu H, Vermund SH. Effects of depression and anxiety on antiretroviral therapy adherence among newly diagnosed HIV-infected Chinese MSM. AIDS 2017, 31: 401-406. PMID: 27677168, PMCID: PMC5233466, DOI: 10.1097/qad.0000000000001287.Peer-Reviewed Original ResearchConceptsImperfect ART adherenceEffect of depressionART adherenceAntiretroviral therapyHIV infectionChinese MSMHIV treatment outcomesAntiretroviral therapy adherenceEnd of studyMixed-effects logistic regressionHIV diagnosisOne-unit increaseProspective studyTherapy adherenceHospital AnxietyRisk factorsTreatment outcomesDepression ScaleSignificant associationIntensive interventionLogistic regressionMSMAnxiety scoresAdherenceInfection
2016
Rates and determinants of incidence and clearance of cervical HPV genotypes among HIV-seropositive women in Pune, India
Mane A, Sahasrabuddhe VV, Nirmalkar A, Risbud AR, Sahay S, Bhosale RA, Vermund SH, Mehendale SM. Rates and determinants of incidence and clearance of cervical HPV genotypes among HIV-seropositive women in Pune, India. Journal Of Clinical Virology 2016, 88: 26-32. PMID: 28152432, PMCID: PMC5441893, DOI: 10.1016/j.jcv.2016.10.013.Peer-Reviewed Original ResearchConceptsHIV-seropositive womenCervical HPV genotypesHPV genotypesClearance rateHPV infectionAge-related hormonal changesRoche Linear Array HPVAlpha-7 speciesAntiretroviral therapy statusCarcinogenic HPV genotypesCervical HPV infectionGenotype-specific prevalenceLinear Array HPVAge of participantsCD4 countHPV incidenceImmunologic factorsDeterminants of incidenceHPV typesTherapy statusProspective studyCervical samplesIncidence rateHormonal changesEtiologic studies
2010
Cost comparison of microscopy vs. empiric treatment for malaria in southwestern nigeria: a prospective study
Parikh R, Amole I, Tarpley M, Gbadero D, Davidson M, Vermund SH. Cost comparison of microscopy vs. empiric treatment for malaria in southwestern nigeria: a prospective study. Malaria Journal 2010, 9: 371. PMID: 21176228, PMCID: PMC3152770, DOI: 10.1186/1475-2875-9-371.Peer-Reviewed Original ResearchConceptsEmpiric treatmentAnti-malarial drugsClinical diagnosisClinical malariaGiemsa smearsMajority of patientsUniversity Teaching HospitalCases of malariaRapid diagnostic testsResource-limited settingsCost of diagnosisBody achesHospital chargesProspective studyTreatment optionsPatient costsPediatric regimenTeaching hospitalDiagnostic confirmationEmpirical treatmentThick smearsClinician judgmentAntimalarial drugsDrug resistanceMalariaCost comparison of laboratory testing vs. empiric treatment for nalaria in Southwestern Nigeria: a prospective study
Parikh R, Amole I, Tarpley M, Gbadero D, Davidson M, Vermund S. Cost comparison of laboratory testing vs. empiric treatment for nalaria in Southwestern Nigeria: a prospective study. Malaria Journal 2010, 9: p36. PMCID: PMC2963277, DOI: 10.1186/1475-2875-9-s2-p36.Peer-Reviewed Original Research
2008
Does douching increase risk for sexually transmitted infections? A prospective study in high-risk adolescents
Tsai CS, Shepherd BE, Vermund SH. Does douching increase risk for sexually transmitted infections? A prospective study in high-risk adolescents. American Journal Of Obstetrics And Gynecology 2008, 200: 38.e1-38.e8. PMID: 18667177, PMCID: PMC3199592, DOI: 10.1016/j.ajog.2008.06.026.Peer-Reviewed Original ResearchConceptsHazard ratioCox proportional hazards modelIncidence of STIsProportional hazards modelAdjusted hazardIncident STIsProspective studyHigh-risk adolescentsHuman immunodeficiencySTI riskIncrease riskHazards modelNext visitSTIsVisitsDouchersFemale adolescentsDouchingAdolescentsInfectionRiskImmunodeficiencyIncidence
2005
Treatment of Intestinal Helminths Does Not Reduce Plasma Concentrations of HIV-1 RNA in Coinfected Zambian Adults
Modjarrad K, Zulu I, Redden DT, Njobvu L, Lane HC, Bentwich Z, Vermund SH. Treatment of Intestinal Helminths Does Not Reduce Plasma Concentrations of HIV-1 RNA in Coinfected Zambian Adults. The Journal Of Infectious Diseases 2005, 192: 1277-1283. PMID: 16136473, PMCID: PMC2730764, DOI: 10.1086/444543.Peer-Reviewed Original ResearchConceptsHIV-1 RNAViral loadPlasma concentrationsAntihelminthic treatmentCopies/Helminth infectionsIntestinal helminthsHigh pretreatment viral loadMedian baseline viral loadPretreatment viral loadBaseline viral loadDysfunctional immune responseIntestinal helminth infectionsHuman immunodeficiency virusMean viral loadCopies/mLHigher helminth burdensPosttreatment visitAsymptomatic adultsImmunodeficiency virusProspective studyZambian adultsUninfected groupHIV-1Immune response
2003
Utility of cervicography in HIV-infected and uninfected adolescents
Moscicki AB, Durako SJ, Ma Y, Darragh T, Vermund SH. Utility of cervicography in HIV-infected and uninfected adolescents. Journal Of Adolescent Health 2003, 32: 204-213. PMID: 12606114, DOI: 10.1016/s1054-139x(02)00461-5.Peer-Reviewed Original ResearchConceptsPositive predictive valuePap smearUninfected groupHigh-risk adolescent populationAdequate Pap smearsLow positive predictive valueRepeat Papanicolaou smearsSingle Pap smearVisit 6 monthsHIV-positive youthHIV-negative youthPositive cervigramHIV infectionCervical cancerProspective studyVisit 1Papanicolaou smearsUninfected adolescentsHIVPredictive valueTime of analysisAdolescent populationCervicography
2001
Virologic and Immunologic Determinants of Heterosexual Transmission of Human Immunodeficiency Virus Type 1 in Africa
Fideli L, Allen S, Musonda R, Trask S, Hahn B, Weiss H, Mulenga J, Kasolo F, Vermund S, Aldrovandi G. Virologic and Immunologic Determinants of Heterosexual Transmission of Human Immunodeficiency Virus Type 1 in Africa. AIDS Research And Human Retroviruses 2001, 17: 901-910. PMID: 11461676, PMCID: PMC2748905, DOI: 10.1089/088922201750290023.Peer-Reviewed Original ResearchConceptsCopies/Heterosexual transmissionRisk ratioMultivariate Cox regression analysisHuman immunodeficiency virus type 1Immunodeficiency virus type 1Plasma viral loadCox regression analysisCorresponding risk ratioHIV-1 RNAVirus type 1Female transmissionCase-control designGender-specific differencesPlasma VLImmunologic correlatesViral loadProspective studySerology resultsWorld's HIVVirus isolationType 1Immunologic determinantsReference groupNontransmitters
1989
A Prospective Study of the Risk of Tuberculosis among Intravenous Drug Users with Human Immunodeficiency Virus Infection
Selwyn P, Hartel D, Lewis V, Schoenbaum E, Vermund S, Klein R, Walker A, Friedland G. A Prospective Study of the Risk of Tuberculosis among Intravenous Drug Users with Human Immunodeficiency Virus Infection. New England Journal Of Medicine 1989, 320: 545-550. PMID: 2915665, DOI: 10.1056/nejm198903023200901.Peer-Reviewed Original ResearchConceptsHIV-seropositive subjectsIntravenous drug usersPositive PPD testHuman immunodeficiency virus (HIV) infectionImmunodeficiency virus infectionActive tuberculosisPPD testDrug usersSeronegative subjectsSeropositive subjectsTuberculous infectionSkin testingVirus infectionHIV-seronegative intravenous drug usersHIV-seronegative subjectsLatent tuberculous infectionRisk of tuberculosisTuberculin skin testingCases of tuberculosisMethadone maintenance programHIV antibodiesHIV-seropositiveHIV infectionProspective studyProtein derivative (PPD) tuberculin
1983
Survival of Schistosoma mansoni in the human host: estimates from a community-based prospective study in Puerto Rico.
Vermund S, Bradley D, Ruiz-Tiben E. Survival of Schistosoma mansoni in the human host: estimates from a community-based prospective study in Puerto Rico. American Journal Of Tropical Medicine And Hygiene 1983, 32: 1040-8. PMID: 6625059, DOI: 10.4269/ajtmh.1983.32.1040.Peer-Reviewed Original ResearchConceptsProspective studyConsecutive stoolsCommunity-based prospective studyGeometric mean egg countQuantitative stool examinationsRitchie concentration techniquesSchistosoma mansoni infectionMean egg countAdult S. mansoniStool countsStool examinationChemotherapy campaignsMansoni infectionStool specimensUntreated individualsRate of declineS. mansoniComplete interruptionCohortSchistosoma mansoniConfidence intervalsHuman hostEgg countsStoolSnail control